PHE have issued their latest surveillance report.

"Case rates increased in all age groups, ethnic groups and regions. Overall Pillar 1 and Pillar 2 positivity increased compared to the previous week, most notably in younger age groups."

A thread
assets.publishing.service.gov.uk/government/upl…
"This week, data on SARS-CoV-2 reinfections in England are being reported for the first time. 15,893 possible reinfections have been identified, of which 53 have been confirmed by identification of genetically distinct specimens from each illness episode."
"COVID-19 hospitalisations increased slightly in week 23. Deaths with COVID-19 decreased in week 23."

(hospitalizations follow cases, deaths follow hospitalizations. This data is for the period ended 13 June.
"COVID-19 vaccine coverage was 56.1% for dose 1 at the end of week 23, reaching over 90% in all cohorts over the age of 65 years and over 80% in all cohorts over 50 years. COVID-19 vaccine coverage was 40.9% for dose 2 at the end of week 23."
"The impact of the vaccination programme is particularly notable in the seroprevalence data which indicates that approximately 79.1% of blood donors aged 17 and over have antibodies to SARS-CoV-2 from either infection or vaccination, ...
" ... compared to 14.8% from infection alone. High levels of seropositivity for vaccination or infection continue to be observed in those aged over 50, as well as increases in those aged 40 to 49 and 30 to 39, following vaccination rollout."
Cases and positivity increasing.
Change in age distribution (a) across the pandemic compared to (b) last two weeks (presumably the vaccine effect)
Case rates increasing particularly in 20-29, 10-19 year olds.
Interesting difference between 20-29 year old men vs women (Pillar 2 tests) - cases rising more in men vs women in this age group.
North-West region showing higer case rates (presumably outbreaks centred around Bolton/Blackburn with Darwen)
Case rates map. Note scale. Cornwall showing an increased rate.
New section on reinfection (defined as "tested positive for SARS-CoV-2 through PCR and/or lateral flow testing with an interval of at least 90 days between two consecutive positive tests")
"15,893 possible reinfections have been identified, of which 53 have been confirmed by identification of genetically distinct specimens from each illness episode."
"It is important to consider reinfections in the context of first infections and there is a 90-day delay before people with a first infection can become eligible for reinfection."
Possible reinfections in blue.
Possible reinfection rate by sex and age.
Incidents
And data caveats
"44 incidents were from care homes where 36 had at least one linked case that tested positive for SARS-CoV-2 where test results were available"

(This is one to be aware of - care homes were mentioned in SAGE minutes)
Food outlet / restaurants increases
Distribution around the country
Hospitalizations increasing (from a low base)
Excess deaths not detected.
Nearly 80% of blood donors have detectable antibodies / seroprevalence. Can see in the divergence in the lines that the vast majority of this comes from vaccination.
Antibodies/seroprevalence - very high (but *appears* to be on a slight downward trajectory but with large error bars so not certain) for over 50s.
Can also see the vaccine effect in 40-49 year olds and 30-39 year olds (but not 17-29 year olds) but still some way to go in 30-39 year olds.
Vaccination. 56% have had 1 dose, 41% have had 2 doses.

Not all who have had their first dose when eligible have had their second dose.
First dose takeup
Second dose takeup (can see that this has been the recent focus of vaccinations)
Vaccine dose 1 takeup by age
Vaccine second dose takeup by age
Vaccine takeup by ethnicity.

**There are still large disparities here**
I will post my heatmaps shortly.
Here are the heatmaps for cases, positivity, hospital and ICU admissions.

Here are the cases and hospitalization charts for today.

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More from @Dr_D_Robertson

17 Jun
A comparison of case rates and hospitalizations at the beginning of the second and the current wave.

(We can't do this for cases in the first wave as mass testing didn't exist.)

A short thread.
In August/September last year, cases started in 20-29 year olds and then moved up to older and younger age groups.
This is the case for this wave: May/June 2021. Cases starting in 10-19 year olds and moving to older and younger age groups. Over this period we see a doubling in 60-69, 70-79, and 80+ age groups but from a *very low base*.
Read 7 tweets
17 Jun
Heatmaps of cases, positivity, hospitalizations, and ICU admissions - data to 13 June published 17 June by PHE.
- cases increasing in all age groups (fanning out from 20-29 year olds)
- low hospitalizations/ICU admissions.
- need to keep watching hospitalizations
Cases increasing in all age groups.
- Note all these charts are coloured against the peak of the (very severe) December/January wave.
- We do not know the vaccine status of these cases.

Nearly 200 cases per 100,000 in 20-29 year olds.
Positivity (Pillar 2). ~4% in 5-9 and 20-29 year old males, 5-9 year old females.
Read 7 tweets
17 Jun
On Cornwall cases and the G7. A short thread.

Cases have risen significantly.
The epicentres of these cases appear to be linked to G7 activity (h/t @_johnbye)
Now, there will be both a lot more activity and a lot more testing due to the G7.

Setting up the venue causes activity and mixing which can spread Covid. Many people will have come from outside Cornwall to help with G7.

Cases started increasing before the G7 main event.
Read 8 tweets
16 Jun
1% (or one in 100) of people in East Darwen were detected as Covid cases this week.
And last week
And the week before that (give or take)
Read 4 tweets
14 Jun
Here is the LSHTM paper on Roadmap Step 4
assets.publishing.service.gov.uk/government/upl…

A central scenario (assuming a delay of 4-5 weeks) bearing in mind there is still uncertainty.

But: a projection in this wave:

*43,500* (between 31,200-62,900) deaths

Peak deaths *500* (between 300-800) per day
Here is a thread giving more detail of the modelling used by LSHTM

Read 7 tweets
14 Jun
Let's look at the SAGE 92 minutes that would have informed the Government's thinking.

A thread.
assets.publishing.service.gov.uk/government/upl…
Additional material has also been released from meetings the previous week.

gov.uk/government/pub…
But back to the SAGE 92 consensus statement.

"R is now estimated to be 40–80% higher for delta than for alpha (B.1.1.7), although a figure higher or lower than this cannot be ruled out. "

*40 to 80%*
Read 17 tweets

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