#Covid19SA
#vaccineswork

Q: How long we have been working on mRNA vaccines?

A: Efforts to create an mRNA vaccine have been ongoing since 1993, when scientists tested mRNA for influenza in mice.
1/
Q: How do vaccines work, in general?

A: Vaccines work by mimicking an infection and training the immune system to recognize SARS-Cov-2 virus.

This training allows the body to respond more rapidly when it encounters the virus in the future.

2/
Q: How do vaccines mimic an infection & train the immune system to recognize the virus?

A: This is usually done by introducing a weakened or inactivated version of the pathogen or parts from it, such as proteins, into the body.
3/
Q: How do mRNA vaccines work?🤔

A: mRNA vaccines take a different approach.

Instead of including a protein from the pathogen or the pathogen itself in the vaccine, they contain the genetic instructions for producing that protein.
4/
Q: What instruction? How?

A: These genetic instructions, known as messenger RNA (ribonucleic acid), are what our cells use as part of the normal machinery to assemble proteins that are needed to keep the cell alive.

5/
Q:What happen when cells receive the instructions?🤔

A:Once the cell receives these genetic instructions, it produces the protein from the virus that can then be used to train the immune system.

The mRNA genetic instructions are DESTROYED by the cell as part of this process
6/
Q: How come we end up having mRNA vaccines? Isn't it much complicated than other vaccines?

A: No!Because mRNA vaccines do not involve any viruses, they can be produced in a facility quicker and cheaper than conventional vaccines that require the viruses to be grown in cells.
7/
Q: What ingredients are in the vaccines?

A: The primary ingredients in Moderna and Pfizer vaccines are the mRNA, lipids, acidity regulators, salts, sucrose (a sugar), and water.
8/
Q: why these compounds are in the vaccine?
A: The lipids is to protect the mRNA until it reaches the cell.

Polyethylene glycol is attached to the lipids to prevent the particles from sticking together and being detected by the immune system.

9/
The acidity regulators, or buffers, keep the pH of the solution at the right level for the body.

The sucrose protects the lipids when they are frozen and prevents them from sticking together.

10/
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More from @Bita33088889

5 Jul
Misinformation about mRNA vaccines!
1.vaccine would “permanently alter your DNA! FALSE

2.spike protein produced by the vaccine would “bind to your DNA and irreversibly change it! FALSE

neither the mRNA nor the spike protein come into contact with our DNA or alter it in any way
3.vaccines will produce more viruses or promote cancer! FALSE

The mRNA introduced through the vaccine survives just long enough to allow the cells to produce spike protein for generating an immune response, aftershock the mRNA will be DESTROYED
2/
4.Vaccinated people shed the spike protein, which could then cause an infection in unvaccinated people nearby. FALSE

It is not possible for the spike protein to cause an infection, that would require a fully-assembled, functional virus.
3/
Read 8 tweets
5 Jul
Covid-19 mRNA Vaccines Are Not ‘Gene Therapy.

What is gene therapy? A technique that “may allow genes to treat or prevent disease.

In the future, this technique may allow docs to treat a disorder by inserting a gene into a patient's cells instead of using drugs.
1/
Who invented this method?

French Anderson was “dubbed 'the father of gene therapy' after a team he led in 1990 cured a hereditary disease of the immune system in a 4-year-old girl.”
2/
For doctors to be able to use gene therapy to treat a disease in a patient, the whole genome of the patient needs to be sequenced!

This method cannot be used for 8Billion people😂
3/
Read 5 tweets
30 May
@DrZweliMkhize
1. Several experts found problematic data in the published phase 1/2 results of Sputnik.

2. Lancet made multiple independent requests for access to the raw dataset, but these were never answered.

thelancet.com/journals/lance…
3. The concern pertains to the trial protocol.

The Sputnik V investigators mention that three interim analyses were added to the study on Nov 5, 2020,1 but this change was not recorded on ClinicalTrials.gov.

The full study protocol has not been made available.
4. Besides these protocol amendments, the definition of the primary outcome is unclear in the Article.

We lack some crucial information, such as the clinical parameters determining suspected COVID-19, diagnostic protocols were used, when the PCR testing was done&...
Read 4 tweets
30 May
#HealthForAll

There are some health screening every woman should do EVERY YEAR!

☆ Blood analysis
☆ Pap smear
☆Breast ultrasound/ Mamigram

Let's break it down.
1/
1. Sceening your blood pressure
☆Starting at age 20: Once every 2 years
☆Adults ages 40 or older: Atleast once per annum
2/
2. Cholesterol Check (Your total cholesterol levels should be <200 mg/dl

Adults 20yr: Once every 5 years.

Adults > 30yr: if your cholesterol is between 200 and 239 mg/dl, make a plan with your doctor for how often you should check it.
3/
Read 12 tweets
30 May
Who should NOT get Pfizer or Johnson vaccine?

According to CDC: If you are allergic to

☆polyethylene glycol (PEG), you should NOT get either of the mRNA COVID-19 vaccines (Moderna or Pfizer).

☆polysorbate, you should not get the Johnson & Johnson vaccine.

1/
If you are allergic to other types of vaccines, for example, the flu shot, you should consult your doctor before scheduling a COVID-19 vaccine.

2/End
CDC recommendations for people with a previous history of allergic reactions👇👇👇

cdc.gov/coronavirus/20…
Read 4 tweets
29 May
Doctors urge people with comorbidities to take Covid-19 vaccine without hesitation:

Diabetic patients
Cancer patients
Cardiac patients
Patients with kidney ailments

Heart failure with hospital admission in past one year

Post cardiac transplant/Left Ventricular Assist Device
1/
Significant Left ventricular systolic dysfunction (LVEF < 40%)

4. Moderate or Severe Valvular Heart Disease

Congenital heart disease

Coronary Artery Disease

Hypertension/ Diabetes on treatment

Angina and Hypertension/ Diabetes treatment

CT/MRI documented stroke patients
2
Pulmonary artery hypertension and Hypertension/ Diabetes on treatment

Diabetes (>10 years or with complication)

Kidney/Liver/Hematopoietic stem cell transplant: Recipient/ On wait-list

End stage Kidney Disease on haemodialysis/ CAPD

3/
Read 7 tweets

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