I want to repeat what others have said:

**If you do not get vaccinated against SARS-CoV-2, you /will/ get infected one day.**

We won't eliminate SARS-CoV-2.
The choice isn't "vaccine or not" - it's "vaccine or infection". This is critical for weighing up risks/unknowns.

1/5
If the mindset is "vaccine or not", it is easy to think that waiting & watching is safer, because you stay in 'nothing happens' territory.

But this isn't accurate. As we see now: unvaccinated people are where cases are spiking & this is going to remain true for a long time.

2/5
I still hear concern from people about the 'unknown long-term effects' of vaccination.

But what I don't hear people also considering is the unknown long-term effects of COVID-19.

Or a fair comparison of the well-known shorter-term effects & risks of both.

3/5
So if you are not yet vaccinated & could be, please sit with this idea: When you get COVID-19, what is your risk?

Because the short-term risks are extremely real & serious - & the long-term damage risk & severity of Long COVID is only just starting to be understood.

4/5
Weighing up our risks is natural, & important. But we must honestly acknowledge what the choices are - & at this point, 'neither' just isn't an option long-term.

Vaccination not only protects you - it protects others.

Now is the time. Please get vaccinated if you can.

5/5

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Dr Emma Hodcroft

Dr Emma Hodcroft Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @firefoxx66

16 Jul
The underlying problem isn't that the UK COVID-19 app is 'too sensitive.'

With a quarter-million cases & few restrictions, even if only correct contacts were pinged, that would be a huge number of alerts & isolations!

And yes - that's going to cause a lot of disruption 🤷🏻‍♀️

1/5
We're papering over the consequences of huge case numbers with debates around sensitivity.

Yes, we can turn sensitivity down - but # of alerts will continue to grow with cases - still potentially annoying people (who uninstall) & certainly continuing to cause disruption.

2/5
This isn't to say we shouldn't try to make pings more accurate, rather, that this isn't an actual solution to high number of pings right now.

Even if 30% pings were bad & we could get perfection now, UK cases rose 33% this week - so we are still at crazy high notifications.

3/5
Read 5 tweets
15 Jul
I've run preliminary @nextstrain focal builds on 20B/S:796H (B.1.1.318) (pictured) & 20A/S:210T (B.1.619).

These aren't part of CoVariants (yet?) but they've caught a couple eyes and I thought it was worth taking a closer look.

1/8 Image
20B/S:796H (B.1.1.318) is behind most of the recent increase in 'other' variants circulating in Greece (shown in grey on the CoVariants plot, below - disregard last point, low sequence #'s).

It's very prominent in Greece, but also found worldwide.

2/8

nextstrain.org/groups/neherla… ImageImage
Taking a closer look at Europe only, we can see there's a large cluster in Greece, but also distinct clusters in Switzerland & Ireland, & many sequences from other countries scattered between.

3/8

nextstrain.org/groups/neherla… Image
Read 8 tweets
7 Jul
🎉CoVariants.org update! 🎉

4 new variants & focal builds added:
- 21G (Lambda) (C.37)
- 21H (B.1.621)
- 20B/S:732A (B.1.1.519)
- 20A/S:126A (B.1.621)

Also - we have awesome new flags on the Per Country page! 🏁🚩

Let's take a closer look...👀

1/10
21G (Lambda) was recently classified a VoI by @WHO & included in @nextstrain builds. It seems to originate in South America - we can see its prevalence in countries like Chile, Argentina, Ecuador, & Peru (purple-pink):

2/10
Looking at the focal build, we can see that 21G (Lambda) has also been found in North America, Europe, the Middle East, and Australia.

Lambda has a unique 7 AA deletion in Spike, & a mutation at S:L452Q.

3/10

nextstrain.org/groups/neherla…
Read 10 tweets
24 Jun
Another brief update: many of the latest focal builds are still baking🥖, but I've gone ahead and pushed up some finished Delta-related runs.

In particular, I wanted to look a little at what's being called 'Delta Plus' = Delta + S:417N mutation

1/9

nextstrain.org/groups/neherla…
S:417N has actually popped up multiple times in the Delta variant - it's of interest because it's thought to be related to immune escape & is also found in Beta.

But looking below, there are 2 main clusters - @PangoNetwork lineages AY.2 & AY.1

2/9

nextstrain.org/groups/neherla…
I don't have 1 build that shows these clusters perfectly yet (working on it!), so we'll use 2 - the focal builds for Delta & S:K417.

Delta: nextstrain.org/groups/neherla…
S:K417: nextstrain.org/groups/neherla…

3/9
Read 9 tweets
24 Jun
🛠️CoVariants.org Update!🛠️

The latest push to CoVariants tweaks how sequences are classified as Variants in some cases, & you'll notice changes in some graphs as a result.

Overall, this change means better classification for lower-quality sequences👍🏻👏🏻

Read on...

1/6
CoVariants looks at nucleotide changes to classify sequences - a sequence must have all of a list of changes to be classified.🧬🔢✅

But sometimes during a sequencing, part of the DNA might not be 'read' ("low coverage"), so we have no information for some locations. ❓

2/6
If some of the positions CoVariants is looking for have low coverage & no information, they won't get classified as Variants. 🧬1⃣2⃣4⃣✖️

This can particularly impact places sequencing lower-quality sequences, as CoV will 'undercount' how many are variants! 📉

3/6
Read 6 tweets
21 Jun
🎉.@WHO and @nextstrain names come to CoVariants.org!🎉

Now it's easier than ever to identify the variant you're interested in - and with beautiful new badges! 🔍

Also, the date plotting on the Per Country page has been made clearer!📈

Let's take a look... 👀

1/4
CoVariants now uses the same clades (including WHO names) you see on Nextstrain.org, making it easy to find a variant of interest!

This comes with beautiful new variant badges - & an updated Name Table that includes Pango & WHO badges, & old CoVariants names! 🎨🌈4

2/4 Image
Of course, this carries over to the Per Country page, where the variant order is also more intuitive. 📜

Additionally, the date axes have been made clearer with more lines, & mouse-over now shows exactly what period the data comes from! 🗓️

3/4 ImageImage
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!

Follow Us on Twitter!

:(