🔮 The BENEFITS of GLYCINE (THREAD - PT I) 🔮
The SINPLEST amino acid, with GARGANTUAN benefits. But...
Glycine's benefits are beyond sleep and vivid dreams.
It's so essential for human health that loss of Glycine transporters to your brain cells...
The SINPLEST amino acid, with GARGANTUAN benefits. But...
Glycine's benefits are beyond sleep and vivid dreams.
It's so essential for human health that loss of Glycine transporters to your brain cells...
Results in the disease "Glycine Encephalopathy",
This shows how important Glycine is for your body. Now...
What makes Glycine so imperative? Why you recover better with Glycine? Why your body uses it for 1000s of processes?
Read on to discover it.
This shows how important Glycine is for your body. Now...
What makes Glycine so imperative? Why you recover better with Glycine? Why your body uses it for 1000s of processes?
Read on to discover it.
Of all 22 amino acids, glycine is THE smallest one.
It has ONE hydrogen forming its side chain (REMEMBER THIS), rather than a Carbon as most aminos.
"Glycine" is derived from the Greek word “glykys”, meaning "sweet" - because Glycine is as sweet as glucose.
fuck sugar 👍
It has ONE hydrogen forming its side chain (REMEMBER THIS), rather than a Carbon as most aminos.
"Glycine" is derived from the Greek word “glykys”, meaning "sweet" - because Glycine is as sweet as glucose.
fuck sugar 👍
The single hydrogen & it's small size gives Glycine AMAZING properties & indispensable roles in our body. For example...
🔮 SKIN HEALTH
Collagen keeps your tissues together, DETERMINES skin physiology, tissues elasticity & strength
"Kola" = "glue"
Collagen = Glue
Aged skin is characterized by...
Loss of COLLAGEN & damaged collagen fibrils. Keep collagen intake high so you age like ✨wine✨[10]
Collagen keeps your tissues together, DETERMINES skin physiology, tissues elasticity & strength
"Kola" = "glue"
Collagen = Glue
Aged skin is characterized by...
Loss of COLLAGEN & damaged collagen fibrils. Keep collagen intake high so you age like ✨wine✨[10]
Collagen is composed of 3 chains of amino acids, creating a Triple Helix.
But EVERY Chain MUST have GLYCINE. Since it's THE smallest amino acid...
Glycine GIVES FLEXIBILITY to the chains. Without this, collagen couldn’t provide support and elasticity to your tissues..
But EVERY Chain MUST have GLYCINE. Since it's THE smallest amino acid...
Glycine GIVES FLEXIBILITY to the chains. Without this, collagen couldn’t provide support and elasticity to your tissues..
And
Glycine's single hydrogen attracts other chain's Glycine Carbon molecules! So...
Glycine "glues" the 3 Collagen Chains, hence, forms the Triple Helix.
If there's No Glycine =
Collagen wouldn’t be a "Glue" for your tissues =
Your body couldn’t held itself together.
Glycine's single hydrogen attracts other chain's Glycine Carbon molecules! So...
Glycine "glues" the 3 Collagen Chains, hence, forms the Triple Helix.
If there's No Glycine =
Collagen wouldn’t be a "Glue" for your tissues =
Your body couldn’t held itself together.
A single genetic mutation, where Glycine no longer fits in Collagen and the Triple Helix becomes disrupted, results in Genetic Disorders in your tissues.
It shows how important Glycine is to Collagen.
If you're an athlete / just work out, I can't recommend Glycine enough.
It shows how important Glycine is to Collagen.
If you're an athlete / just work out, I can't recommend Glycine enough.
🧬- ANTI-AGING, ANTIOXIDANT
Glutathione (GSH): A POWERFUL endogenous antioxidant, it prevents Inflammation and Oxidative Stress
Oxidative Stress is a imbalance between Reactive Oxygen Species (ROS) and your body's Antioxidants
Inflammation increases, Disease arise... No bueno!
Glutathione (GSH): A POWERFUL endogenous antioxidant, it prevents Inflammation and Oxidative Stress
Oxidative Stress is a imbalance between Reactive Oxygen Species (ROS) and your body's Antioxidants
Inflammation increases, Disease arise... No bueno!
HIGH GLUTATHIONE is as essential as HIGH GLYCINE levels, you see....
No Glycine = No GSH.
The "Gamma Glutamyl Cycle" brings together:
- Cysteine,
- GLYCINE
- & Glutamine into...
Your liver cells to SYNTHESIZE GSH. Take one out of the equation and there's no GSH.
No Glycine = No GSH.
The "Gamma Glutamyl Cycle" brings together:
- Cysteine,
- GLYCINE
- & Glutamine into...
Your liver cells to SYNTHESIZE GSH. Take one out of the equation and there's no GSH.
This study shows that Cysteine and Glycine supplementation FULLY RESTORES GLUTATHIONE synthesis in ELDER PEOPLE - they usually have dysfunctional glutathione synthesis!
Imagine what Glycine will do for a young king like you. GSH through the roof.
academic.oup.com/ajcn/article/9…
Imagine what Glycine will do for a young king like you. GSH through the roof.
academic.oup.com/ajcn/article/9…
Another study found EXACTLY the same result.
"Precursor supplementation in elderly subjects led to a...
94.6% higher glutathione concentration
230.9% higher absolute synthesis rate AND...
Significantly lower plasma oxidative stress."
"Precursor supplementation in elderly subjects led to a...
94.6% higher glutathione concentration
230.9% higher absolute synthesis rate AND...
Significantly lower plasma oxidative stress."
"A 90min. excercise routine can cause a 50-70% depletion of bloodstream and liver’s Glutathione”
It's IMPERATIVE that u replenish Glutathione after training.
Glycine + Electrolytes + MgCl + B1 + Kefir + Collagen =
DOMS? Fatigue? Nice joke mate
pubmed.ncbi.nlm.nih.gov/3768007/
It's IMPERATIVE that u replenish Glutathione after training.
Glycine + Electrolytes + MgCl + B1 + Kefir + Collagen =
DOMS? Fatigue? Nice joke mate
pubmed.ncbi.nlm.nih.gov/3768007/
🍽 FAT DIGESTION
Bile Acids (BAs) are stored & released by your GALLBLADDER to the small intestine. They're needed to DIGEST FAT.
BAs break down big fat globules into smaller droplets, which are further broken down into Fatty Acids by Lipase (digestive enzyme) for absorption
Bile Acids (BAs) are stored & released by your GALLBLADDER to the small intestine. They're needed to DIGEST FAT.
BAs break down big fat globules into smaller droplets, which are further broken down into Fatty Acids by Lipase (digestive enzyme) for absorption
Most Bile Acids ONLY are synthesised by adding a GLYCINE MOLECULE to their structure (Process is called conjugation).
Remember Glycine's single hydrogen?
It creates Hydrogen Bonds with WATER molecules. Glycine's Hydrogen bonds with Oxygen!
Remember Glycine's single hydrogen?
It creates Hydrogen Bonds with WATER molecules. Glycine's Hydrogen bonds with Oxygen!
So BAs' water solubility, flow through small intestine & Fat-breaking activity...
IMPROVES with Glycine.
Bile Acids can also be conjugated with Taurine and guess what?
Taurine also has a single hydrogen in it's side chain.
IMPROVES with Glycine.
Bile Acids can also be conjugated with Taurine and guess what?
Taurine also has a single hydrogen in it's side chain.
However, it must be a 3:1 ratio of Glycine & Taurine.
Cholic Acid & Chenodeoxycholic Acid make up 80% of all bile acids
72-76% of BOTH are conjugated with GLYCINE and just 25% with Taurine
If you have issues digesting fat, check this THREAD🧬✨
Cholic Acid & Chenodeoxycholic Acid make up 80% of all bile acids
72-76% of BOTH are conjugated with GLYCINE and just 25% with Taurine
If you have issues digesting fat, check this THREAD🧬✨
https://twitter.com/realalejandroAD/status/1417926154556559360?s=20
🥃 - ALCOHOL PROTECTION [24]
Glycine accelerates the first-pass elimination of alcohol by the stomach thus preventing alcohol from reaching the liver
After induction of Alcoholic Hepatitis, GLYCINE SPEEDS UP RECOVERY.
Why?
Glycine accelerates the first-pass elimination of alcohol by the stomach thus preventing alcohol from reaching the liver
After induction of Alcoholic Hepatitis, GLYCINE SPEEDS UP RECOVERY.
Why?
Because Glycine REDUCES Inflammation in THE LIVER too!
Most liver cells have Glycine Receptors (GlyR). Since glycine is immuno-modulatory...
Most liver cells have Glycine Receptors (GlyR). Since glycine is immuno-modulatory...
by the FUCKING way think how you'll feel with a FULL PROTECTION against ALCOHOL...
Something like a ...
ANTI-HANGOVER ELIXIR - Recover from Alcohol like ZEUS 🧬✨
patreon.com/posts/52187697
Something like a ...
ANTI-HANGOVER ELIXIR - Recover from Alcohol like ZEUS 🧬✨
patreon.com/posts/52187697
Now, Since Glycine is immune modulatory...
Exactly. It controls inflammation and ROS production in your liver.
Glycine reduces ALCOHOL-induced liver damage, removes LIPID perOXIDATION injury and fixes GLUTATHIONE deficiency caused by toxins [24].
And about inflammation...
Exactly. It controls inflammation and ROS production in your liver.
Glycine reduces ALCOHOL-induced liver damage, removes LIPID perOXIDATION injury and fixes GLUTATHIONE deficiency caused by toxins [24].
And about inflammation...
🌋 INFLAMMATION CONTROL
Inflammation is a immune response to harmful stimulus: Pathogens, Injury, Metabolic stress, Anti-nutrients, nutrient deficiencies. It's function?
To restore your body's normal state, to retvrn homeostasis.
However, you want CONTROL.
Inflammation is a immune response to harmful stimulus: Pathogens, Injury, Metabolic stress, Anti-nutrients, nutrient deficiencies. It's function?
To restore your body's normal state, to retvrn homeostasis.
However, you want CONTROL.
Uncontrolled, high inflammation = The Root of All Disease.
Everything from Cancer to Depression, from Leaky gut to Alzheimer, from Joint Pain to Diabetes, from Fatigue to Cardiovascular disease, have High Inflammation as a root cause.
Everything from Cancer to Depression, from Leaky gut to Alzheimer, from Joint Pain to Diabetes, from Fatigue to Cardiovascular disease, have High Inflammation as a root cause.
Interestingly...
Glycine Receptors (GlyR) can be found in PRO-INFLAMMATORY CYTOKINES, suggesting that Glycine is inflammation-controlling. Let's go deeper:
Glycine Receptors (GlyR) can be found in PRO-INFLAMMATORY CYTOKINES, suggesting that Glycine is inflammation-controlling. Let's go deeper:
A study published on FASEB showed that...
Glycine DECREASES Lipopolysaccharide (bacteria toxins) induced Inflammatory Cytokine RELEASE (TNF-a and IL-1b) AND RAISES anti-inflammatory cytokine, Interleukin-10!
pubmed.ncbi.nlm.nih.gov/10064624/
Glycine DECREASES Lipopolysaccharide (bacteria toxins) induced Inflammatory Cytokine RELEASE (TNF-a and IL-1b) AND RAISES anti-inflammatory cytokine, Interleukin-10!
pubmed.ncbi.nlm.nih.gov/10064624/
NF-kB attaches to your DNA and triggers YUGE inflammatory activity throughout the body. It's elevated during Chronic Inflammation, causing a Vicious Cycle.
Guess what?
Guess what?
Glycine inhibits activation of NF-kB in different inflammatory-conditions, including hemorrhage and Septic Shock. Glycine increases survival rates, recovery & protects against Organ Injury during a Septic shock [25].
Glycine supplementation blocks ROS formation caused by phthalates (endocrine disruptors) and HYDROGENATED CORN OIL [3]
So yes. Glycine modulates inflammation & prevents excessive levels. Impressive. Very Nice.
(The "why" is after next section)
So yes. Glycine modulates inflammation & prevents excessive levels. Impressive. Very Nice.
(The "why" is after next section)
🦵 - ARTHRITIS
Itis = Inflammation. Since Glycine controls it, eventually it'll improve Arthritis.
Here, "PG-PS" (bacteria toxins) was injected in rat's ankles.
This induces arthritis in rats since it triggers IL-1, IL-6 & TNFa release (inflammatory cytokines).
Itis = Inflammation. Since Glycine controls it, eventually it'll improve Arthritis.
Here, "PG-PS" (bacteria toxins) was injected in rat's ankles.
This induces arthritis in rats since it triggers IL-1, IL-6 & TNFa release (inflammatory cytokines).
3 days prior injection, rats were fed a Glycine rich diet OR a Control diet. Guess what happened with the Glycine diet?
Correct. It had a better response. Inflammation was ATTENUATED since TNFa increase was BLUNTED AND it's release was INHIBITED by GLYCINE.
Correct. It had a better response. Inflammation was ATTENUATED since TNFa increase was BLUNTED AND it's release was INHIBITED by GLYCINE.
Ankle diameter increased 50% MORE in Control compared to the Glycine group.
In most cases, Joint Pain just reflects the quality of your diet. Shit diet full of seed oils, sugar and anti-nutrients + lack of sunlight, movement & micronutrients = Joint Pain
In most cases, Joint Pain just reflects the quality of your diet. Shit diet full of seed oils, sugar and anti-nutrients + lack of sunlight, movement & micronutrients = Joint Pain
Anti-TNFa therapy is the most efficient drug strategy in arthritis treatment nowadays. So if Glycine is a HUGE TNF inhibitor...
Yes.
It's a potential great treatment for Joint issues (alongside an anti inflammatory lifestyle).
Yes.
It's a potential great treatment for Joint issues (alongside an anti inflammatory lifestyle).
🏃♂️ - GLYCINE IMPROVES METABOLIC HEALTH
Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance.
Glycine = LonFUCKINGgevity
hindawi.com/journals/omcl/…
Glycine Increases Insulin Sensitivity and Glutathione Biosynthesis and Protects against Oxidative Stress in a Model of Sucrose-Induced Insulin Resistance.
Glycine = LonFUCKINGgevity
hindawi.com/journals/omcl/…
"Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine"
ncbi.nlm.nih.gov/pmc/articles/P…
ncbi.nlm.nih.gov/pmc/articles/P…
Calpain, activated by High Intracellular Calcium. Calpains promotes CELL DEATH (apoptosis) and Cytoskeleton DEGRADATION.
And hey, what triggers calcium release? Oxidative stress & Inflammation.
And... what INHIBITS calcium release?
Glycine (and magnesium)
And hey, what triggers calcium release? Oxidative stress & Inflammation.
And... what INHIBITS calcium release?
Glycine (and magnesium)
Glycine, through the GlyR, lets Chloride get INTO your cells. Since Chloride is a "-" mineral, it reduces a cell's electrical charge, lowering excitation and...
LOWERS CALCIUM.
Glycine is health protection on its finest.
LOWERS CALCIUM.
Glycine is health protection on its finest.
🍔 - GLYCINE & DIABETIC COMPLICATIONS
Glycine DECREASES the formation of Amadori products, precursors to the advanced glycation endproducts (AGEs), responsible for most diabetic complications.
AGEs are formed when proteins or fats COMBINE with SUGAR (glucose/fructose).
Glycine DECREASES the formation of Amadori products, precursors to the advanced glycation endproducts (AGEs), responsible for most diabetic complications.
AGEs are formed when proteins or fats COMBINE with SUGAR (glucose/fructose).
High blood sugar (hyperglycemia) + Poor Insulin Sensitivity accelerates AGEs production = accelerates disease.
Glycine IMPROVES BLOOD SUGAR, INSULIN SENSITIVITY, reduces AGEs AND increases Antioxidant status.
Hi "CICO" dorks aha
Glycine IMPROVES BLOOD SUGAR, INSULIN SENSITIVITY, reduces AGEs AND increases Antioxidant status.
Hi "CICO" dorks aha
In this study, diabetic bros with auditory neuropathy had improvements in hearing acuity + auditory nerve conduction with JUST GLYCINE (20g daily for 6 months).
The fact that Diabetic complications improved, without drugs, should be on the news evey single day
The fact that Diabetic complications improved, without drugs, should be on the news evey single day
🎏 GLYCINE SUPPLEMENTATION, DOSAGES & INTOLERANCE
If at this point u r not consuming Glycine before bed, u either:
-Don't follow @Solbrah
- are cringe n blue pilled
-or you are ok with not having vivid dreams and DEEP, REJUVENATING sleep.
las 3 NO son aceptables.
If at this point u r not consuming Glycine before bed, u either:
-Don't follow @Solbrah
- are cringe n blue pilled
-or you are ok with not having vivid dreams and DEEP, REJUVENATING sleep.
las 3 NO son aceptables.
Why yes ur body can synthesise it. But since it's used for A LOT of reactions,
It's insufficient to meet demands without extra Glycine.
Low glycine intake through the years can result in delayed, suboptimal growth, fucked up immune responses and accelerated aging [7]
It's insufficient to meet demands without extra Glycine.
Low glycine intake through the years can result in delayed, suboptimal growth, fucked up immune responses and accelerated aging [7]
Glycine + Hydrolized Collagen Peptides is a MUST, specially for gym bros/athletes. It'll give your body abundant materials to grow and repair everyday.
Several clinical trials use dosages high as 0.8g per Kg without side effects. With that said, I've found 3-18g the sweet spot. Start at lower end, increase slowly. I do 5-15g before bed, usually 9g.
The ABSOLUTE BEST and most based Glycine supplement?
Sol Supps' Glycine.
Everytime I consume it my cock grows 10 meters. I teleport to ATLANTIS during my dreams. Your sleep issues can disappear this week if you integrate this to your life.
solsupps.com/shop/p/glycine
Sol Supps' Glycine.
Everytime I consume it my cock grows 10 meters. I teleport to ATLANTIS during my dreams. Your sleep issues can disappear this week if you integrate this to your life.
solsupps.com/shop/p/glycine
(im not aff, I just need to recognize a quality product when I try one)
Some react poorly to Glycine. They feel excited, anxious, get insomnia or like "something's off". I was one of those
2 years ago I took 600mg of MgGly before bed and I slept 2 hours that night lmaooo
Some react poorly to Glycine. They feel excited, anxious, get insomnia or like "something's off". I was one of those
2 years ago I took 600mg of MgGly before bed and I slept 2 hours that night lmaooo
Now I get 5-15g before bed, usually 9g. I have vivid dreams and wake up reCHARGED.
A "glycine intolerance" isn’t a intolerance TO glycine. You just lack THE nutrients to use it properly.
A "glycine intolerance" isn’t a intolerance TO glycine. You just lack THE nutrients to use it properly.
Glycine can excite your brain, so you must have enough B1, Mg & B6 to prevent a Glutamate increase. Probiotics, sunlight, less blue light & zero sugar too.
These factors are needed for Glutamate to G.A.B.A. conversion AND in excess glutamate break down. If u don't have em in check, Glycine will raise glutamate & cause excitation.
Magnesium Chloride 2-4g through the day and 2-5g before bed. 11mg Elemental Magnesium x KG everyday. MgCl & MgGly = 25% & 14& MgEl, respectively.
Benfothiamine. Start with 150mg at breakfast and lunch, increase 150mg daily until 1.2-1.8g. Eat seafood, eggs, kefir, organ meats on a daily basis to metabolize B1 correctly without side effects.
Eat seafood, eggs, kefir, sardines & organs for B6.
Eat seafood, eggs, kefir, sardines & organs for B6.
On PT. II, I’ll cover WHY GLYCINE is ESSENTIAL for SLEEP.
You literally need Glycine for deep, restorative sleep. Without it, you’re NOT sleeping as good as you could.
Meaning
You’re not working out, gaining muscle, losing fat, thinking & living as good as you could.
You literally need Glycine for deep, restorative sleep. Without it, you’re NOT sleeping as good as you could.
Meaning
You’re not working out, gaining muscle, losing fat, thinking & living as good as you could.
You’ll also discover a sinple trick to avoid “Glycine Excitation” and ENSURE that Glycine has its desired effects.
2 years ago, Glycine triggered anxiety and insomnia in me. Now the total opposite.
Join me on Patreon to get EARLY ACCESS and…
2 years ago, Glycine triggered anxiety and insomnia in me. Now the total opposite.
Join me on Patreon to get EARLY ACCESS and…
Access to II THREADS on IMPROVING YOUR SLEEP. This is THE SLEEP SAGA.
Vanish Insomnia, Post-sleep tiredness and achieve Vivid Dreams.
Your sleep issues can disappear this week if you join.
✨🧬 SLEEP SAGA: THE SCIENCE BEHIND IT & HOW TO IMPROVE IT 🧬✨
patreon.com/posts/sleep-sa…
Vanish Insomnia, Post-sleep tiredness and achieve Vivid Dreams.
Your sleep issues can disappear this week if you join.
✨🧬 SLEEP SAGA: THE SCIENCE BEHIND IT & HOW TO IMPROVE IT 🧬✨
patreon.com/posts/sleep-sa…
This was Alejandro. See ya on PT II.
oh yeah retweet this bad boy btw
LETS FUCKING GO
LETS FUCKING GO
https://twitter.com/realalejandroad/status/1419491698456080384
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