Higher levels of omega-3 acids in the blood increases life expectancy by almost five years

Huge result, though association only - causation not shown

I want to show how this implicates seed oils in mortality

sciencedaily.com/releases/2021/…
Original paper

Similar results have been seen in several other studies.

While this is framed as benefits of consuming fish or fish oils, the omega-3 index also depends on the consumption of omega-6, abundant in seed oils academic.oup.com/ajcn/advance-a…
Omega-3 index is a measure of the amount of omega-3 in red blood cells

When omega-6 consumption is high, omega-3 index is low

Omega-3 fatty acids EPA and DHA in tissues decreases with higher omega-6 content Image
Omega-6 content in tissues increases with increasing consumption of seed oils, and omega-3 index declines

One estimate is that omega-3 index has declined by ~60% during the 20th century due to increasing seed oil consumption

academic.oup.com/ajcn/article/9… Image
In different populations, tissue omega-6 correlates with coronary heart disease mortality.

So, higher omega-6 (seed oil) consumption leads to lower omega-3 index, which is associated with higher mortality Image

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More from @Mangan150

6 Aug
Whenever you say that some allegedly incurable chronic illness was cured by diet, exercise, fasting, or some other natural means, you always see a large contingent of people who insist that's not possible, or that it's really "remission", or that it won't work for everyone.
No one says it will work for everyone.

That can't possibly be an objection to trying it, or trying to spread the word about the possibility of a cure.

By objecting to this, these people are doing serious harm
Because these objections can make people feel they shouldn't try to fix themselves.
Read 6 tweets
5 Aug
Long-term NAC treatment attenuated flu-like symptoms. 2 x 600 mg NAC per day for 6 months, most subjects >65 years old.

25% of those taking NAC reported symptoms vs 79% of placebo.
N-acetylcysteine is cheap and is, for now, OTC, though the FDA is trying to restrict it. Amazon has removed NAC for example.
Read 4 tweets
4 Aug
Berberine prevents atherosclerosis in animals through improved gut barrier function and reduced inflammation.

This tweet is not about berberine.
Intestinal barrier dysfunction as a therapeutic target for cardiovascular disease

But, they told us it was all about cholesterol

pubmed.ncbi.nlm.nih.gov/32986965/
Read 4 tweets
1 Aug
Seed oils and cancer

High intake of omega-6 PUFAs is implicated in cancer of the breast, colon and, possibly, prostate

Omega-3 PUFAs and monounsaturated fatty acids such as oleic acid (omega-9) are protective.

pubmed.ncbi.nlm.nih.gov/10590211/
Mammary tumorigenesis [in mice] was very sensitive to linoleate [seed oils' main component] intake and increased proportionately in the range of 0.5 to 4.4% of dietary linoleate.
cancerres.aacrjournals.org/content/45/5/1…
Most Americans consume enough seed oils that they're above a plateau in cancer causation. In other words, they're exposed to the maximum cancer-promoting amount.

This may be why associational studies are inconclusive: almost no one consumes a low level of linoleic acid
Read 4 tweets
28 Jul
Seed oils (aka vegetable oils) and atherosclerosis leading to coronary heart disease

How could that work?

Let's take a look 👇
Oxidized LDL cholesterol is thought to play a critical role in formation of arterial plaques

Macrophages (white blood cells in the blood vessel wall) sense oxLDL, engulf it, leading to plaque formation

hindawi.com/journals/omcl/…
The oxidized fatty acid in oxLDL is mainly linoleic acid, the main component of seed oils

sciencedirect.com/science/articl…
Read 8 tweets
26 Jul
Niacin reduced mortality by 14% in men with metabolic syndrome.

That's great, but results would be far better if they got rid of metabolic syndrome.

Eliminating sugar, seed oils, and grains, and adding resistance training.
pubmed.ncbi.nlm.nih.gov/16461040/
Metabolic syndrome raises all-cause mortality rates by 50 to 100%

Crap food + sedentary lifestyle -> metabolic syndrome.

Around half of Americans age 50 and up have it.
ahajournals.org/doi/full/10.11…
No drug or natural product will be as affective as proper exercise and eliminating garbage food.
Read 4 tweets

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