1/ Just finished reading “A Statin Free Life” by @DrAseemMalhotra. A very interesting book and for those of you currently taking Statins who are fearful of stopping Statins, this is a good place to start. If I was doing a review I would give the book 9 out of 10.

/2
2/ For people who have ditched their Statins, there is great comfort and reassurance that you have made the right decisions so far. There is a case study which starts on page 54, of a Pilot who had a heart attack and was prescribed the standard cocktail of drugs
3/ to treat heart disease. He was exceptionally smart/intelligent and he unilaterally decided to cease taking all these medications, despite the fact that he had a 99% blockage in the circumflex artery. The drugs made him so ill that he decided to research

/4
4/ the biochemistry underpinning these drugs and elected to stop the Statin immediately. The other drugs were also phased out one by one after careful consideration of their potential benefit vs harm. If and when you get the book, please read page 58

/5
5/ and also his decisions regarding BP lowering meds and beta blockers. He came off ALL of them after doing the research, and since 2016 is off all the heart meds. His most important metabolic markers now reveal a huge improvement, thanks to following a LCHF diet.

/6
6/ I think you will enjoy the book.

In the summer of 2018 this same man successfully completed his first Ironman, 3.5 years after his heart attack and 2.5 years after stopping all his medications. It's inspirational !

/7
7/ The only criticism I have is that you cannot substitute 20mg of Atorvastatin for 80mg of the same drug and expect plain sailing. These drugs are toxic to EVERY cell in the body. They destroy cell membranes and at the 80mg dose cause autoimmune disease.

/8
8/ The dose determines the rate of progression the type of disease & the poison. There is no doubt that at 20mg damage happens, just more slowly. I would say it’s absolute nonesense that Statins are in any way useful in those who have already experienced a a heart attack

/9
/9 Yes, Statins have pleiotropic anti-inflammatory effects, but these are FAR FAR outweighed by the risks.

I’m also not a great fan of the recipes at the end of the book. I would be looking to see far more LCHF recipes, sans porridge !

/10
10/ Read the book and make up your own mind. It’s a very interesting read, and overall I think Aseem has done a wonderful job in raising awareness and assessing the benefits/risks of Statin drugs. It's available on Amazon. It could save your health, or even your life ! 😃
@PaulusK52 Get the book for your neighbour !

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More from @holmanm

13 Sep
1/ We show that Statin-induced insulin resistance is a drug CLASS EFFECT. Cerivastatin was removed from the market because of "side effects". Our results show that Cerivastatin was the most potent Statin in promoting adipose insulin resistance.

/2
2/ "We show that statins impaired insulin-stimulated lipogenesis in an adipocyte-autonomous manner, which was prevented by supplementing isoprenoids required for prenylation". WHY ??

/3
3/ because Statins interfere with the Mevalonate pathway & deplete so many organic compounds with great structural diversity and functionality.

- and you can't always put back what Statins stole in the first place. The overriding message is
Stay away from Statins.
Read 4 tweets
9 Sep
1/ Apoptosis (cell death) is an essential component of the maintenance process of our bodies. It is a highly controlled and regulated technique for removing unwanted cells from any organ by the process of induced metabolic suicide.

/2
2/ Tinkering with this process is a potentially catastrophic game. This is the game of Russian Roulette that we play when we take Statins.
That good old law of unintended consequences could have a field day here.

/3
3/ Statins promote apoptosis. They do it in diseased tissues - Cheers for Statins. Unfortunately they ALSO do it in NORMAL tissues too; Boo for Statins.
Read 8 tweets
9 Sep
1/ Where do you find the highest concentration of cholesterol in your whole body ? YUP ! In your brain.

Although the brain represents only 2% of total body weight, it contains 20% of the body’s cholesterol. What is all that cholesterol doing up there ?
/2
2/ Synapses - where communication between brain cells takes place are lined by cholesterol-rich membranes responsible for passing neurotransmitters like serotonin, GABA, and dopamine back and forth.

/3
3/ Myelin, the white matter that insulates brain circuits, is made from tightly-wound membranes containing 75% of the brain’s cholesterol. Cholesterol also helps guide developing nerve endings to their destinations on “lipid rafts”.
/4
Read 4 tweets
5 Sep
1/ Someone sent me a DM a few days ago "what range should our cholesterol be" ? I think it’s important to stress that cholesterol reference ranges are merely an average of the general population, and that traditional populations with NO heart disease have healthy cholesterol

/2
2/ levels which are often much much HIGHER than the baselines for Western Societies. Reversing insulin resistance by lowering fasting blood sugar, and lowering inflammation by dietary changes is a far more sensible approach than lowering cholesterol.

/3
3/ Total cholesterol is a TOTALLY MEANINGLESS number, since it doesn’t tell you what that cholesterol is made up of, but guidelines say it should be around
250mg/dL - ( 6.465 mmol/l)

LDL cholesterol 130mg/dL ( 3.3618 mmol/l)

HDL cholesterol 60mg/dL (1.5516 mmol/l)

/4
Read 5 tweets
2 Sep
1/ GABAPENTIN ! Yeah another great drug according to Docs and Veterinary surgeons: "This is what I have since learned about the drug: Stanford University did a study on gabapentin in 2009 and found that it prevents the formation of new synapses in the brain.
2/ Many who take it long-term eventually develop cognitive impairment and short-term memory loss. Gabapentin affects GABA (gamma-aminobutyric acid—a “calming” element) in the body. When taking the drug, one’s body will adjust to the artificially induced GABA and start to

/3
3/ produce less of its own. (That fact is similar to benzodiazepines except that gabapentin affects GABA through calcium receptors rather than GABA receptors.)

Though not technically addictive, dependency can happen very quickly. If taken incorrectly, stopped abruptly,

/4
Read 6 tweets
2 Sep
1/ SOS ! Can any of my followers or anyone connected to the veterinary industry help me.? If not can you please give this an RT to reach out. I have a friend who has a dog which has Osteosarcoma. It has now been revealed that there is a hairline crack in the bone.
/2
2/ It has been suggested that intravenous Bisphosphonate treatment is the solution. I disagree because I did my research years ago when I was diagnosed with Osteoporosis. What I found was that Bisphosphonates increase mineralisation and reduce the ability to absorb energy

/3
3/ which could result in accumulation of micro-cracks. The mechanism by which BPs cause osteonecrosis is probably due to a combination of decreased bone remodelling, poor wound healing, and an antiangiogenic effect leading to ischaemic changes and subsequent

/4
Read 5 tweets

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