A mechanistic model of the neural entropy increase elicited by #psychedelic drugs 1/5 doi.org/10.1038/s41598…
#Psychedelic drugs, including lysergic acid diethylamide and other agonists of the serotonin 2A receptor (5HT2A-R), induce drastic changes in subjective experience, and provide a unique opportunity to study the neurobiological basis of consc... 2/5
iousness. One of the most notable neurophysiological signatures of #psychedelics, increased entropy in spontaneous neural activity, is thought to be of relevance to the psychedelic experience, mediating both acute alterations in consciousnes... 3/5
s and long-term effects. However, no clear mechanistic explanation for this entropy increase has been put forward so far. We sought to do this here by building upon a recent whole-brain model of #serotonergic neuromodulation, to study the en... 4/5
Date: October 2020 Authors: Rubén Herzog, Pedro A M Mediano, Fernando E Rosas, Robin Carhart-Harris, Yonatan Sanz Perl, Enzo Tagliazucchi, Rodrigo Cofre 5/5
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