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26 Sep, 5 tweets, 1 min read
DMT alters cortical travelling waves 1/5 doi.org/10.7554/eLife.…
#Psychedelic drugs are potent modulators of conscious states and therefore powerful tools for investigating their neurobiology. N,N, Dimethyltryptamine (DMT) can rapidly induce an extremely immersive state of consciousness characterized by v... 2/5
ivid and elaborate visual imagery. Here, we investigated the electrophysiological correlates of the DMT-induced altered state from a pool of participants receiving DMT and (separately) placebo (saline) while instructed to keep their eyes cl... 3/5
osed. Consistent with our hypotheses, results revealed a spatio-temporal pattern of cortical activation (i.e. travelling waves) similar to that elicited by visual stimulation. Moreover, the typical top-down alpha-band rhythms of closed-eyes... 4/5
Date: October 2020 Authors: Andrea Alamia, Christopher Timmermann, David J Nutt, Rufin VanRullen, Robin L Carhart-Harris 5/5

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Views on Drugs Profile picture
27 Sep
Post-#Psychedelic Reductions in Experiential Avoidance Are Associated With Decreases in Depression Severity and Suicidal Ideation 1/5 doi.org/10.3389/fpsyt.…
#Psychedelic therapy shows promise as a novel intervention for a wide range of mental health concerns but its therapeutic action is incompletely understood. In line with acceptance and commitment therapy's (ACT's) transdiagnostic model, qual... 2/5
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26 Sep
#Psychedelics and virtual reality: parallels and applications 1/5 doi.org/10.1177/204512…
#Psychedelic drugs and virtual reality (VR) each have the capacity to disrupt the rigidity and limitations of typical conscious experience. This article delineates the parallels among psychedelic and VR states as well as their potential syne... 2/5
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26 Sep
Whole-Brain Models to Explore Altered States of Consciousness from the Bottom Up 1/5 doi.org/10.3390/brains…
The scope of human consciousness includes states departing from what most of us experience as ordinary wakefulness. These altered states of consciousness constitute a prime opportunity to study how global changes in brain activity relate to... 2/5
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25 Sep
A mechanistic model of the neural entropy increase elicited by #psychedelic drugs 1/5 doi.org/10.1038/s41598…
#Psychedelic drugs, including lysergic acid diethylamide and other agonists of the serotonin 2A receptor (5HT2A-R), induce drastic changes in subjective experience, and provide a unique opportunity to study the neurobiological basis of consc... 2/5
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25 Sep
On Revelations and Revolutions: Drinking #Ayahuasca Among Palestinians Under Israeli Occupation 1/5 doi.org/10.3389/fpsyg.…
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25 Sep
From Psychiatry to Neurology: #Psychedelics as Prospective Therapeutics for Neurodegenerative Disorders 1/5 doi.org/10.1111/jnc.15…
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