1. Only that I'm very busy these days preparing for a manuscript submission, but I think this Preprint has a great need to be analysed and its findings put in the bigger context. @TChivese medrxiv.org/content/10.110…
2. As usual, the media hypes one specific narrative despite the authors themselves advocating for more work to avoid skew and bias. I suggest we hold a Space more like a Journal Club discussion. People get 1 week to read the paper contact authors if they want then we discuss.
3. This is purely an academic exercise, to really get into the intestines of the paper and ask the hard questions and interrogate everything. @TinofaMutevedzi@SibandaSibbs@TChivese@mdimairo@llgonde what say ye? Everyone is welcome to attend with questions or additions.
4. Remember it is not about winning an argument but interrogating this paper or rather Preprint and we can even send our comments to the authors too... Unless they have already published it, but that still works too
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1. "Zimbabwe’s aviation system had, since 2010, operated without a surveillance system, the air traffic controllers told the CAAZ board." newsdzezimbabwe.co.uk/2021/09/privat…
2. "Investigations also established that the South African aviation authority has, at times, picked potential collisions in Zimbabwean air space and alerted local ATCs."
3. “They (ATCs) highlighted that … CAAZ and ACZ (Airport Company of Zimbabwe) are allowing airports to operate without the presence of ATCs and that there is a disaster in the making,” the minutes noted...
Thread from an article that is no longer available online 1. "THE 2013 elections in Zimbabwe were rigged!!!
Some might choose to call it election
engineering.
2. Until a few weeks ago, I had also
begun to mistakenly believe that indeed Zanu
PF had won the last election fair and square,
until I started scratching the surface, combing
through 2013 election results as posted on the
ZEC website, looking for the needle in the
haystack
3. Seek and ye shall find! I slowly began
finding anomaly after anomaly. And the more I
pulled at the strings, the more the mystery
unravelled. I am going to apologise in advance
for the length of this article, but there is a lot of
information I have to disseminate to the public
1. Contrary to what other people are saying, I think the expressions of frustration and impatience are not to be silenced but harnessed. ZImbabweans for too long have been ok with just doing their own thing but there is an awakening that our only problem in Zim is ZanuPF.
2. I urge people to be calm and not to rush to dismiss each other but in fact find each other. There is a part we have to play as citizens, we have to form groups, think tanks and action plans. There are many opportunities on what to do outside a political party.
3. We can have community groups, organize them. Non-violence is the key. But strategic thinking is required. Unless we reach a critical mass of people who really want change we will keep outsourcing to others.
1. The headline is very simplified, it suggests that scientists are making actual small brains... Which is not necessarily the case. This is how conspiracy theories start😂 neurosciencenews.com/alzheimers-bra…
2. Organoids are made from the patient's cells through a process of cell engineering which is essentially cell culture. So you take a skin cell and then treat it with some chemical composition (transcription factors) to reprogram it to a brain cell.
3. What has been learnt so far is that, the miniature clump of cells you reprogram replicate the or are faithful to the genetic make up of the individual. If a person has Zika, their reprogrammed cells organize in a way reflective of their disease condition🤯
1. Whilst what Mwonzora said is highly regrettable, it is also a reflective of the culture in academic institutions. Some universities don't accept training obtained from other institutes in the country. It is a form of elitism that is damaging and limits sharing of skills
2. I witnessed at least 2 people, well qualified and highly skilled being denied positions on the basis that the prevailing perception at the institution was that they got their qualifications from an "inferior" institution.
3. When you then go inside the institution, there is a further discrimination of people based on what degree they did...it is almost like we have an unending loop of ego inflation. This is one of the things that severely repulsed me about academia.
@realmedicaldoc@drjaytee87@TChivese
Loooooong thread... 1. IVM and HCQ when you look at the mechanism of action and where they act in the pathway of viral infection, it is logical and scientific to try their use. However, the key issue comes to the clinical trials.
2. To make claims on efficacy of a drug, there is a standard level of evidence which has to come through carefully designed and rigorous trials so that the level of evidence is not doubted or questioned. I will put down some of the summaries from the main studies below
3. Randomized, double-blind, placebo-controlled trial in Cali, Colombia (n = 476) IVM (n = 200) and placebo (n = 198) in primary analysis. Key limitation small sample size, primary endpoint modified, sample size composition, only 4 hospitalized patients out of 398,high IVM dose