I haven't read the other trials yet, but between the 6-month results of Modern and Pfizer we have, summed together, 31 vaccine deaths and 30 placebo deaths.
How many do we need to get statistical power for an all-cause mortality effect? Can we do that if we sum all the trials?
How many do we need to get statistical power for an all-cause mortality effect? Can we do that if we sum all the trials?
This has to keep in mind that the total mortality in the US was said to increase 17% last year, with 69% of that due to COVID, and the trials while primary prevention are done in high risk populations due either to age or comorbidities.
Population data predicts an 11% excess risk of death that the vaccines should wipe out 98% of.
Maybe @AviBittMD can do a power calculation? If not I'll try one when I actually get around to safety and efficacy.
Maybe @AviBittMD can do a power calculation? If not I'll try one when I actually get around to safety and efficacy.
For now, onward on transmission!
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