So it’s our first HOT TOPIC

The convalescent plasma arm of @remap_cap

Currently on channel 1 at #lives2021
@remap_cap Inclusion criteria below

Intervention: 2u convalescent plasma vs standard care
@remap_cap Patient demographics and primary outcome (composite outcome)

No benefit seen in this study
@remap_cap Secondary outcomes/subgroup analysis

#lives2021
@remap_cap Conclusion #lives2021

There will be a subgroup study in the immunosuppressed- watch this space...

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More from @iceman_ex

6 Oct
Soon to be published in @yourICM:

A consensus statement on head to toe ultrasound skills in the general and neuro ICU population

Massive piece of work led by @AVBmir @chiara_robba and @avkwong

Building on stuff published here ccforum.biomedcentral.com/articles/10.11…

#lives2021 Image
@yourICM @AVBmir @chiara_robba @avkwong After Delphi a decent consensus was reached- here are some summaries
1. Cranial ultrasound- TCCD guided PI is weakly recommended as a BASIC skill (over ONSD)
2. Lung US- strong recommendations for PTX, Effusion, and consolidation

#LIVES2021 ImageImageImageImage
@yourICM @AVBmir @chiara_robba @avkwong Airway ultrasound for intubation is weakly recommended AGAINST
Diaphragmatic excursion is weakly recommended FOR, with no consensus on diaphragmatic thickening
Lots of strong recommendations for LV assessment to be basic (including RWMA) with no consensus on TOE

#lives2021 ImageImage
Read 4 tweets
5 Oct
Ok. @ESICM #lives2021 🔥 HOT TOPIC 🔥

Results of the HYPO-ECMO study- therapeutic hypothermia post cardiogenic shock requiring ECMO

clinicaltrials.gov/ct2/show/NCT02…
Physiological rationale and clinical question ImageImage
Study design and end points

Primary =30 day mortality

#LIVES2021 ImageImage
Read 6 tweets
5 Oct
Now watching: @RKleinpell discussing digital strategies in family care

#LIVES2021 Image
@RKleinpell Our changed visitation policies had…consequences #lives2021 Image
@RKleinpell Katerina Iliopoulou on the consequences of restricted visiting… #LIVES2021 Image
Read 5 tweets
5 Oct
Want to learn how to review a paper?

Check out @HalliePrescott on channel 7

Your first two questions should be:
1. Accept or reject?
2. How do I optimise this paper for acceptance?

Recommended reading: atsjournals.org/doi/10.1513/An… ImageImage
@HalliePrescott Recommends learning from Jean-Luc Dumont on scientific communication presentationzen.com/presentationze…

#LIVES2021
@HalliePrescott Think about the core of the article:

What
How
Why

#LIVES2021 Image
Read 8 tweets
2 Jun 20
Webinar is now LIVE. I’ll be providing some coverage on Twitter.
@DrMCecconi is describing his experience.

It’s been written up here jamanetwork.com/journals/jama/…

And he did a superb webinar with @JAMA_current where he spoke directly from the front lines esicm.org/blog/?p=2626
@DrMCecconi @JAMA_current Current data from Italy

Case fatality rate 13%
Read 27 tweets
17 Apr 20
Fascinating discussion from the @ICS_updates webinar

Differing opinions on HFNC, CPAP and intubation

The risk of P-SILI described by @bjoern_weiss

Versus the benefits of avoiding intubation

Again: NO ONE can predict who will successfully manage with noninvasive therapies.
Up to 50% of patients will manage with noninvasive therapies alone (CPAP/HFNC)

But which 50%? Does everyone warrant a trial? And where should this trial take place?

#icswebinar #covid19foam
The discussion around PEEP is ongoing

SuperPEEP is out. A modest level of PEEP (8-10) is suggested by @deoxyexplorer

Superdry for fluid balance is also out- euvolaemia is current target.

#icswebinar #covid19foam
Read 9 tweets

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