Top 10 drugs for Medicare Part D spending in 2019. The list and the $ amounts are worrisome:
1 is used for a cancer that's 1% of all cancers.
2 are expensive blood thinners more convenient, but only marginally better than older drugs.
4 are diabetes drugs.
Insulins should not be on that list. It's 2021.
A drug that's a cousin I thalidomide, that has been used for over 15 years to treat a cancer that's only 1% of all cancers should not be on the list.
I don't think new oral blood thinners should be so highly priced.
Medicare does get back some money back for these drugs as rebates so we don't know the exact dollar amount which Medicare actually spends. But the spending is high regardless.
Of course all of the drugs are single source: monopoly, with only one manufacturer making each drug. They dictate the price coz Medicare cannot negotiate.
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Bottomline is that some drop in efficacy against infections is seen over time, but protection against severe illness remains constant. Vaccines are working great in this study as in multiple others which have demonstrated the same thing.
We have 280 million people eligible for COVID vaccines in the US.
The first 140 million got fully vaccinated ASAP. The final stretch will be the hardest.
See the rocket take off and then slow to a crawl.
I thought some people may be reluctant. But not this much: 95 million eligible but not yet fully vaccinated.
30 million of these have had one dose. So I am hopeful they will get fully vaccinated soon.
That leave 65 million eligible people who have not had even one dose yet.
Out of these even if one third has some degree of immunity from prior COVID, it still leaves 40 million eligible people completely susceptible. That is a lot of people.
Which is why we cannot relax yet. What we can do below:
Not all drugs with only one manufacturer are a monopoly. That's why some of single source drugs are lower priced. If an alternative drug is available from another manufacturer, there's competition; many equivalent drugs, especially generic equivalents, means real competition.
On the other hand, if a new cancer drug works for only a few months or years, and then stops working - the case with most cancer medicines - then even if there are multiple meds EACH drug remains a monopoly. Because we want to try each drug and prolong life the most we can.
We had 5 months of declining deaths after vaccines. After all, the proportion who were unvaccinated & susceptible existed during these months as well. But delta was just settling in
Once delta established itself, we are at >2000 deaths/day.
Whatever protection we had against original strain of Covid, disappeared with delta. delta was more transmissible. Taking off masks too early didn't help.
Deaths are very high with delta, but we would have faced a much bigger crisis without vaccines.
Based on Israel study on effect of vaccines in reducing deaths and hospitalizations, and knowing what happened in India, we probably saved >100,000 lives in the US because of vaccinations. thelancet.com/journals/lanin…