1) For people worried about H5N6: Zoonotic infections with influenza viruses happen all the time. They may lead to severe disease and death in exposed individuals but as long as there is no human to human transmission....
2)....there is little to worry from a global perspective. Of course we need to keep an eye on them and prepare prototype vaccines (which is something that has been done for many of these viruses). Here is a slide that shows how often these zoonotic infections are found. It is....
3)....a little outdated, but I think you get the idea - it happens often. Purple are viruses with associated human cases, blue are viruses that should be watched because they caused remarkable outbreaks in animals. H2N2 is in red because it has caused a pandemic in the past....
4)...and is still around in birds (it disappeared from the human population in 1968). So we know it can do it and we are always worried about it. On the plus side, everybody born before 1968 is probably immune against it. Sometimes being older does have benefits 😉 
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