📍Folks need to know this—#ColinPowell had multiple myeloma—a cancer of plasma cells that **makes antibodies**. Thus, vaccines are weaker in myeloma patients because we kill the cells that make antibodies with our myeloma treatments. Please vax to protect others.🧵

HT @VincentRK
2) Where are the studies proving this? Myeloma patients are extremely weak responders to vaccines because we killed off the immune cells to treat the cancer.
3) myeloma cancer patients have very very weak immune systems, and well known to have high COVID mortality already because of it.
4) Vaccines hence work weaker in myeloma because of treatment kill the plasma cells. Only 45% of active multiple myeloma patients developed an adequate response, while 22% had a partial response.

nature.com/articles/s4137…
5) Interestingly, although, most MM patients have impaired responses to mRNA vaccination against COVID-19, ➡️ myeloma patients who received Moderna vaccine had higher anti-spike antibody levels than those who were vaccinated with Pfizer!!! Moderna is clearly the stronger vaccine.
6) This is the most sloppy tweet I’ve seen from NYT in a long time. Cmon @nytimes— you can do better. Must mention he had myeloma!!!
7) NYT @nytimes needs to have more stricter editorial editing of its tweets from now on for medical current events news. Burying the detail he had myeloma cancer is irresponsible nytimes.com/live/2021/10/1…
8) Cancer patients really need the 100 mcg #Moderna vaccine. It’s much much stronger than 30 mcg Pfizer shot.
9) Among #MultipleMyeloma cancer patients…. It’s a 6x fold higher antibody response with 2 shots of 100 mcg Moderna than versus 2 shots of Pfizer…. 👇
10) Let’s honor #ColinPowell and other immunocompromised by #vaccinating. Please, think of others, not just yourself. When our family and community crumbles, we all suffer. Great thread 🧵 by @ASlavitt 👇

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More from @DrEricDing

19 Oct
For the “kids are practically immune” crowd out there…. is this 2-year old intubated on a ventilator for 5 days—an “acceptable” level of kids illness? Zero kids are supposed to be intubated nor die. Zero. #COVID19 goodmorningamerica.com/wellness/story…
2) Anyone who says we need to “learn to live” with the virus needs to visit the memorials of all those who have died and tell me exactly just how many flags is “acceptable” for their their partying and social life.
3) we don’t “learn to live” with suffocating pillows or cribs. We should not learn to live with 20 kids a week dying of COVID last month as something that we should ever repeat!
Read 5 tweets
19 Oct
So, I worry kids vaccine rollout might hit supply bottlenecks—➡️ latest info says it will not be possible to simply use existing adult Pfizer vaccine stock to draw up 1/3 adult dose, to use for kids. Kids shots will come in *new 10-dose vials*—to be still shipped out!🧵 #COVID19
2) The reason we cannot just cut the adult dose is that doing so would result in an injection volume of 0.1mL, which is considered too small for intramuscular injection. Instead, there will be a new diluted formulation of the vaccine for use in age 5-11—0.2mL doses with 10 mcg
3) Initial doses will be allocated to the states, which will then direct them to individual practices and perhaps other locations. Doctors offices and pharmacies will be able to request doses, but are not guaranteed to receive the number they request.
Read 6 tweets
18 Oct
I don’t recall any leader who say we should “LEARN TO LIVE” with Ebola, rabies, or HIV. We shouldn’t “learn to live” with #COVID19 either. If we do, this is the price we will pay for years to come 👇, plus maim an entire generation with #LongCovid.
2) We don’t live with iron lung machines because we vaccinated and have nearly eliminated polio.
3) we don’t “learn to live” with suffocating pillows or cribs. We should not learn to live with 20 kids a week dying of COVID last month as something that we should ever repeat!
Read 5 tweets
18 Oct
📍JUST IN—FDA is planning to allow people to receive a different #COVID19 vaccine as a booster than initially received. Recent NIH study shows J&J recipients who got a Moderna booster saw antibody levels ⬆️76-fold in 15 days, vs 4x after an extra J&J shot.
nytimes.com/2021/10/18/us/…
2) Federal regulators this week are aiming to greatly expand the number of Americans eligible for booster shots. The F.D.A. is expected to authorize boosters of the Moderna and Johnson & Johnson vaccines by Wednesday evening; it could allow the mix-and-match approach by then.
3) An advisory committee of the Centers for Disease Control and Prevention will take up the booster issue on Thursday; the agency will then issue its own recommendations. By the end of the week, tens of millions more Americans could be eligible for extra shots.
Read 6 tweets
18 Oct
📍FACT: Popcorn 🍿 is the number one whole-grain in the American diet. Whole grains are health and prevent diabetes, heart disease and strokes. But…

📍SAD FACT: Most popcorn eaten is buttered🧈 or salted🧂

📍SADDER: Microwave🍿 can cause lung 🫁 scarring if hot fumes inhaled.
2) That bag of microwave popcorn may smell good, but it's best to let the bag cool before you open it.
“Popcorn lung” is an irreversible scarring of the smallest airways in the lungs…
cspinet.org/tip/do-you-ris…
3) It’s caused by inhaling vapors of a buttery-tasting chemical that some manufacturers used to add to microwave 🍿. Diacetyl is a natural compound found in cheese, butter, yogurt, & wine. It’s not harmful when swallowed, but it can damage the lungs if large amounts are inhaled.
Read 4 tweets
18 Oct
Medical schools are infamously bad at teaching epidemiology. Utterly absent or completely rudimentary teaching of epidemiology. It’s a miracle if medical doctors learn any biostatistics (very different from college “coin flip” statistics). Just beware when reading #COVID stats.
2) Many medical schools have zero courses in epidemiology and zero courses in population biostatistics. I had attended medical school myself years ago (before I withdrew) and examined school curriculums—it’s very lacking. Some doctors are smart and self learn, but most don’t.
3) This is a not criticism of MD/DO doctors - they have to learn so much with a firehose volume of information to memorize already. But it is a reality of medical schools in prioritizing some topics over more useful ones like epidemiology which they need to know to read research.
Read 11 tweets

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