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Eric Feigl-Ding Profile picture
@DrEricDing
Oct 29, 2021 • 14 tweets • 6 min read • Read on X
⚠️BREAKING—REINFECTION & NATURAL IMMUNITY—new CDC study in hospitalized adults finds: unvaccinated people with prior #COVID19 infection recently were **5 times more likely** to be reinfected / get breakthrough versus people recently fully vaccinated! 🧵 cdc.gov/mmwr/volumes/7… Image
2) Here’s the background—
Previous infection with SARS-CoV-2 or COVID-19 vaccination can provide immunity and protection against subsequent SARS-CoV-2 infection and illness. ➡️ but the big debate has been which immunity is stronger? Offers more protection? That’s the study aim.
3) “Among COVID-19–like illness hospitalizations among adults aged ≥18 years whose previous infection or vaccination occurred 90–179 days earlier, odds of laboratory-confirmed #COVID19 among unvaccinated adults with previous SARS-CoV-2 infection were 5.49-fold higher”…
4) …”than among fully vaccinated recipients of an mRNA COVID-19 vaccine who had no previous documented infection (95% confidence interval = 2.75–10.99).” Wow 👀

📌 Notably this was a clean comparison of fully vaccinated with no prior infection vs those with prior infection!
5) What are the implications for public health practice?

📍All eligible persons should be vaccinated against COVID-19 as soon as possible, including unvaccinated persons previously infected with SARS-CoV-2. ⚠️
6) Let’s dive into #DeltVariant and reinfection from natural immunity vs breakthroughs by vaccination— reinfection via natural infection is 7.55x higher than breakthroughs!!! Image
7) What about vaccine type? Reinfection risk is 5x higher with natural immunity vs Pfizer vaccine. But reinfection risk is 7.3x higher with natural immunity vs Moderna! Moderna is again stronger protection and natural immunity much much weaker. 👀 Image
8) Among elderly, natural immunity is almost 20x weaker against reinfection than vaccines!! ⚠️ But even among 18-64, natural immunity is still 2.57x weaker protection than vaccines!! ⚠️ Image
9) Someone warned about this exact issue over a month ago…. Some naysayers had dismissed it because it was not peer reviewed or from CDC. But it was clear vaccine immunity had less breakthroughs than natural immunity had reinfections.
10) to be clear—even if natural immunity had equal reinfection risk as vaccine had breakthroughs—vaccines would still be better. Because it is much much safer. And don’t forget the selection bias in natural infection—that “dead men tell no tales” where you only measure survivors.
11) Thus, natural immunity should be called “NATURAL INFECTION SURVIVORS” who survived an earlier infection. That’s why when even if “natural immunity” people higher antibodies—you’re selecting people who didn’t succumb last time. ➡️And also don’t forget #LongCovid debilitation.
12) But folks who tout natural infection focus on those who *survived*, and they know they had COVID often by looking at just those with enough antibody response in antibody tests! Many survivors **who don’t mount antibodies are often excluded** from studies! Hence it’s biased!
13) Wow- 1 in 4 infected with COVID do NOT develop antibodies! There goes natural immunity strategy — it’s not reliable! Hence get #vaccinated!
14) We should not be talk about natural or artificial immunity at all. Vaccines stimulate your own natural immunity to fight #SARSCoV2 and other viruses. That’s how they work. What “natural immunity” folks really want to say is “let’s mass infect everyone” for expediency. 👀

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Feb 26
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain. Image
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 26
Doctors are debunking RFK Jr’s claim that 20 hospitalized measles cases in Texas are there for mainly quarantine. Doctors on the ground say the 20 kids hospitalized are having trouble breathing. Oh and they are all unvaccinated against measles, which RFK Jr neglects to mention. Image
2) RFK Jr told Trump today there’s now 2 measles deaths.
3) RFK Jr is a tear with his FDA today. A dark Darwinian future lies ahead for America.
Read 4 tweets
Eric Feigl-Ding Profile picture
Feb 26
BREAKING—Reports coming in about potentially *2 measles deaths* in Texas, not just one, according to an HHS briefing to the White House today.
2) Earlier today, one measles death in an unvaccinated child was reported in Texas. Image
3) It seems to be RFK Jr who said it in an official Trump WH cabinet meeting today. Not saying he doesn’t lie, but he is now HHS Secretary
Read 6 tweets
Eric Feigl-Ding Profile picture
Feb 21
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏 Image
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2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”

pmc.ncbi.nlm.nih.gov/articles/PMC10…
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 16
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)Image
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2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)."
nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.

"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"Image
Read 13 tweets
Eric Feigl-Ding Profile picture
Feb 14
⚠️WORST FLU SEASON ever since 2002-2003 when we began to track flu (red, first graph). Worst hit this year are children ages 0-4 and 5-17. ▶️We also have significantly LOWER flu vaccine uptake this year, one of the lowest flu vaccine coverages (red 3rd graph). Indisputable facts. Image
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2) I don't need to tell you that certain US states have vastly lower vaccination rates than others. See map (lighter green, less flu vaccination coverage), and which have higher (darker green)...

If you want to see details and demographics on which state has the LOWEST flu vaccine coverage rates... the data is here.
cdc.gov/fluvaxview/das…Image
3) It’s not just the flu that is going around… Gaines County, TX, where the epicenter of the measles outbreak is, has one of the lowest measles vaccination rates too.
Read 7 tweets

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