A 68 year old man presents with weight loss and dysphagia for 6 weeks. Upper endoscopy is shown. What is your diagnosis? #MayoIDQ and case details to follow
2/ 68M. No PMH. 6w gradual dysphagia to solids with 20 lb weight loss. No F/C/sweats. PE: cachexia. WBC 4.7 Cr 0.9 CXR normal. HBV(-). Rx fluconazole.
Per your suggestion: HIV VL 56K CD4 26. Patient willing to start ART immediately. Genotype pending. You suggest which one?
3/ Case diagnosis: Esophageal candidiasis in a man with newly diagnosed AIDS
Suggested ART: TAF-FTC-bictegravir
ART consists of 2 NRTI in combo with 3rd drug: INSTI, NNRTI or boosted PI.
Among them: INSTI is preferred for various reasons (next)
2/ #Plasmodium#falciparum 1. Anopheles bite 2. Endemic regions / returning travelers: 12-14 day incubation period 3. Fever +/- severe symptoms (see next) 4. Dx: blood smear, rapid diagnostic Ag or Ab test 5. Rx: chloroquine, artemisin-based combination Rx (depends on region)
A young man presents to the ER because of leg numbness. While undergoing evaluation, he had a seizure. CT head is shown (photo). #IDTwitter what is your differential diagnosis?
2/ Four months after mild COVID-19, an ICH man with CLL on obinutuzumab presents with prolonged / recurrent doxycycline-non responsive CAP. CT chest shown. See prior tweet for other details. Which of the following is the most likely diagnosis? #MayoIDQ
3/ All of the MCQ choices could be possible in this case. Imaging suggested viral or PJP.
Work up:
Serum BDG / GM negative
CMV PCR negative
BAL PJP PCR negative
BAL SARS-CoV-2 PCR +++
SARS-CoV-2 spike/nucleocapsid Ab negative (despite infection / vaccine)