A young man presents to the ER because of leg numbness. While undergoing evaluation, he had a seizure. CT head is shown (photo). #IDTwitter what is your differential diagnosis?
2/ Four months after mild COVID-19, an ICH man with CLL on obinutuzumab presents with prolonged / recurrent doxycycline-non responsive CAP. CT chest shown. See prior tweet for other details. Which of the following is the most likely diagnosis? #MayoIDQ
3/ All of the MCQ choices could be possible in this case. Imaging suggested viral or PJP.
Work up:
Serum BDG / GM negative
CMV PCR negative
BAL PJP PCR negative
BAL SARS-CoV-2 PCR +++
SARS-CoV-2 spike/nucleocapsid Ab negative (despite infection / vaccine)
Who is the host? What is the most likely pathogen? How do you treat? #MayoIDQ
2/ #MayoIDQ
75F. Immunocompetent.
CC: headache x few months —> now left leg weakness, blurred vision, seizure. CBC/CMP normal. CT head: mass in right ventricle, pons. CT chest/abdomen for CA work up (-). Brain biopsy (photo).
Which of the following is the most likely pathogen?
#MayoIDQ#IDBR
45M CC: tender mass on left thigh that started as an “insect bite” 4 days ago. No F/C. PE: tender fluctuant 2-cm mass with surrounding erythema.
After I&D of abscess in the clinic, what do you recommend?
2/ 2014 IDSA guideline recommends incision and drainage of purulent SSTI (abscess)
Antibiotics vs MRSA / S. aureus as an adjunct to I&D if: 1. SIRS 2. Failed initial Ab Rx 3. Impaired host defense
3/ After 2014 IDSA guideline, placebo-controlled RCTs were published on use of antibiotics (TMP SMX or clindamycin) for uncomplicated SSTI abscess ... (next)