Long Thread - With the new variants one from Botswana and the Second #C13 from South Africa , I am reminded of an old post @hjelle_brian ,@DrEricDing
For a variant to win against the Delta means a new Sumo wrestler is in town and that it has the potential ability to wipe out some of the herd immunity that we have achieved from the Delta .@PrinSciAdvGoI ,@narendramodi,@shekhar_mande ,@OfficeOf_MM

Ctd 3) Also the second variant of interest from Botswana is another one growing ,that means India should immediately stop flights from Africa and also again look at the travel hubs that have flights coming from Africa eg Dubai@HardeepSPuri,@JM_Scindia

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More from @Rpshahmemorial1

27 Nov
Will try and keep everyone posted on the new developments on Omicron , the last thread became too lengthy in a day .But this is the information we had on 25/ 26 Nov. Ctd
Ctd2) I believe that it has become imperative that we immediately start finding whether the combination of Merck's Molnupiravir &Pfizers Antiviral is effective against Omicron?? we have had reports of Molnupiravir dropping efficacy yesterday in full trial.@hjelle_brian ctd)
@hjelle_brian Ctd3) virologists consider that the virus is " stealing " parts of our RNA as @hjelle_brian, to me it seems that these are efforts of virus to get past Interferons which are our defence mechanism .We know that those with Anti Interferon antibodies have bad course #Omicron ctd) Image
Read 9 tweets
26 Nov
Long thread 1) There is this fear about the new Botswana/ Nu/ B1.1.159 variant but let's delve into why is this fear?? The 4 cases they found in Botswana were all vaccinated.So what??Breakthrough happens all the time,we underestimate incidence @hjelle_brian ctd) Image
Ctd2) This variant marked in blue is coming up , so what?? These variants will come and go. Ist it was the Wuhan strain in Grey , then the Beta ( SA strain in Green , then the Delta in Red and now may be the Botswana variant in Blue ( B1.1.529) @MoHFW_INDIA, @mansukhmandviya ctd) Image
Ctd3) For the virus and also the vaccines ( Pfizer/ Moderna/ AZ) the spike protein is the most important and that is where the maximum risk is . The Delta had 2 changes in spike proteins Receptor Binding Domain, the Beta had 3 while the Nu has 10 , so there is a real risk ctd)
Read 23 tweets
25 Nov
Long thread -As a Surgeon I am painfully aware how difficult it is for a surgeon to work with a new anesthesist,or to work with new assistants/get work done in a new set up or with new nurses,there is a critical element of camaraderie, the team works like an oiled machine ctd)
Ctd2) A gentle grunt here , a small nudge there , you extend your hand and the instrument is in ur hand these arent luxuries, they put the mind of everyone at ease and causes better results in CRUX situations. HOWEVER the pandemic has disrupted these synergies@HalfwayKnown ctd)
Ctd3) Nurses are leaving , doctors & nurses are falling sick, some dying and others suffering from Long Covid. You just cannot simply replace a team member and expect them to perform, it takes time for them to settle in @DustyEnfermera,@NursesOntario ,@NursesWhoVax ,@NurseTexas
Read 7 tweets
24 Nov
Long post ) It has been my sudden realization that even though we knew all along since last 1.5 yr plus that airplanes are the biggest source of transfer of new variants @JimRosenthal4 , @kprather88 but instead of doing more about trying to prevent in flight infection we ctd)
@JimRosenthal4 @kprather88 Ctd2) we continued our apathy towards the same . Masking is important BUT as I have always maintained it has to be N95 masks in flight , we know that for every person infected there is a chance to infect occupants until 2 rows before and behind, worser this is pre Delta info ctd)
Ctd3) The same hasn't been updated , the Canadians at least did make an effort to try finding this out but haven't seen anything since last 6 months .Also we need to lay down the rules of inflight contamination levels @DrAxelrod_WHO ,@WHO ,@WHOEMRO ,@WHOSEARO ,@DrRabiWHO ctd)
Read 6 tweets
16 Nov
Long thread -The JVC recommendations, Telegraph story and apathy from Govts across the world on Covid in kids has me seething with rage ,2014 report sciencedirect.com/science/articl… @LongCovidKids ,@LCKScotland, @bees_oz ,@chrischirp,@dgurdasani1 ,@LCKCanada,@LCKIreland ,@kidsCovidGamble
Ctd2) clearly from the paper 15 kids were lost to flu when we introduced Flu vaccines in kids across UK.And how many do we have now , over a hundred have already been lost forever, a hundred families will stay up on Christmas eve and mourn, Santa will not visit those homes ctd)
Ctd3) This year flu shots have been expanded across UK . Why ?? 1) Govt wants to reduce flu levels in population BUT doesnt want to reduce Covid cases ?? 2) Vaccines against flu save kids and society both Ain't the same be said about Covid Vaccines .@TigressEllie, @Tall_Paul_05
Read 5 tweets
16 Nov
Long thread but some background first - I am a Pediatric Orthopedic Surgeon and have treated kids with special needs for the last 15 years, my wife is a gynecologist @fogsiofficial ,@narendramodi , @PMOIndia, @mansukhmandviya ,@OfficeOf_MM , @PrinSciAdvGoI , @shekhar_mande ctd)
@fogsiofficial @narendramodi @PMOIndia @mansukhmandviya @OfficeOf_MM @PrinSciAdvGoI @shekhar_mande Ctd) @BhallaAjay26 , @MoHFW_INDIA,@drharshvardhan and we have for last 15 years ensured that the kids we treat have the best solutions across the world , the pandemic has brought a new challenges @LongCovidKids ,@LCKScotland , @LCKCanada,@LCKIreland ,@Bodalicious1,@UTc19LongHaul
Ctd3) This long term advocacy of the rights of children with special needs is not our hobby ,its a life long committment and passion for our team .ctd)
Read 8 tweets

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