Will try and keep everyone posted on the new developments on Omicron , the last thread became too lengthy in a day .But this is the information we had on 25/ 26 Nov. Ctd
Ctd2) I believe that it has become imperative that we immediately start finding whether the combination of Merck's Molnupiravir &Pfizers Antiviral is effective against Omicron?? we have had reports of Molnupiravir dropping efficacy yesterday in full trial.@hjelle_brian ctd)
@hjelle_brian Ctd3) virologists consider that the virus is " stealing " parts of our RNA as @hjelle_brian, to me it seems that these are efforts of virus to get past Interferons which are our defence mechanism .We know that those with Anti Interferon antibodies have bad course #Omicron ctd)
@hjelle_brian Ctd4) While the world over people clamor to get back to homes , it is but easy that the #Omicron is finding more and more piggybacks @rubyslippahs ,@fitterhappierAJ ,@fitterhappierAJ ,@PMGPSC,@AllergyKidsDoc, @Allergygal1 ,@richdavisphd , @AyushmanHWCs ,@YouAreLobbyLud
Ctd5) With 15 positive from 110 tested , seems that the 600 will have close to 90 , I agree. THEN in addition there will be others who WILL CATCH IN QUARANTINE.
Ctd6) While there has been discussion about #VaccineEquity that has lead to the unfortunate situation there is also another side that we haven't considered. The vaccine hesitant. We need to push on all fronts #OmicronVariant @UNAIDS_ESA ,@AfricaHealthFed
reuters.com/world/africa/e…
@UNAIDS_ESA @AfricaHealthFed Ctd7) Months ago we called out efforts to underplay deaths in Africa ,these stories give rise to Vaccine Hesitancy.Stories like the one below have contributed to #OmicronVariant .It is not always about #VaccineEquity which is very important. @dgurdasani1
indiatoday.in/coronavirus-ou…
@UNAIDS_ESA @AfricaHealthFed @dgurdasani1 Ctd9) If I were in the place of Potus I would push for boosters as hard as I could along with mandates , the next set of vaccines are at least 3 months to go and #Omicron would still be
amenable to boosters, doesn't loom like complete immune escape reuters.com/business/healt…
Ctd 10) And that brings me to the proponents of Herd Immunity,those who have maintained that Herd Immunity has come since the last 6 months to a year need to remember that it hasn't @SunetraGupta . Only by means of vaccines have we been able to control
.collateralglobal.org/article/mini-l…
Ctd 11) Meanwhile England's chief medical officer Chris Whitty has said his "greatest worry" is whether people will accept fresh curbs on activities to tackle #Omicron he questioned whether "we could take people with us" if restrictions had to be imposed.#BetterPersuasion ctd)
Ctd11) Apparently at the moment the information is that the infected have 75% unvaccinated and 25% vaccinated group, even amongst the infected breakthrough cases the patients are less severe . 🤞🤞. Early information. @emilygraymd_mph ,@rubyslippahs,ctd)
@emilygraymd_mph @rubyslippahs Ctd12) And a good tweet to understand why just RTPCR at arrival is not enough , people can get infected in between the time they give the sample and the results, they were in a hall herded like sheep @DrEricDing , @ersmith2016 ,@nvcmenon ,@MoHFW_INDIA
@emilygraymd_mph @rubyslippahs @DrEricDing @ersmith2016 @nvcmenon @MoHFW_INDIA Ctd13) And this @trvrb thread shows that he feels it has come from an immunocompromised person , while he feels that not from SA , this is disputable because the SA genome consortium looked at data from those who were able to get RTPCR @hjelle_brian
Ctd14) And if the calculation @trvrb
is perfect ( we hope not ) then it has seeded all across the world by now and has short doubling time.
Ctd15) In a lesson for most countries banning people on flights from 6 Nations India has cast the net wider, ensuring that all permutations and combinations that can be made are covered with RTPCR,also we accept #COVIDisAirborne@takesthecake2 ,@AirQ007,@CorsIAQ,@Dr2NisreenAlwan
Ctd16) The Czech Republic and Germany both find one suspected case each .Contact tracing for all travelers within the last 1 month should be undertaken if possible, throughout is going to be tough ,almost impossible to do .
Ctd17) Across the world people who have championed the cause of kids have been scoffed at during the pandemic, long Covid in kids has been undermined and deaths in kids have been tied to comorbid conditions.Apparently #Omicron is more in kids and young .
Ctd18) As I said earlier that #Omicron looks bad in the simulation experiments , there is also now " PseudoVirus" simulation that have been done wherein a dummy virus with spike protein changes has been checked against plasma of people who have been saved & post vaccinated ctd)
Ctd19)The simulation shows that #Omicron will probably escape natural immunity and vaccines BUT those vaccinated and infected once may escape #OmicronVariant
Ctd20) 2 In UK and 2 tentatively in India , looks like a movie being rerun after a year 😢😢
Ctd21) The problem of vaccine hesitancy is not only in SA , sadly it is rampant across African continent. reuters.com/business/healt…
Ctd22) Seems that the disease is causing exhaustion and profound weakness in young adults and kids , what happens in elderly is not known by this news report. telegraph.co.uk/global-health/…
Ctd23) Israel acts fast .Finds 7 suspected cases - 3 In community,3 from those who have travelled recently , acts on the premise that it is there across the globe ( agree 100% ). Enforces mandatory Quarantine.
aljazeera.com/news/2021/11/2…
Ctd24) Israel reintroduces Phone tracking apps , these are the war games that they practised a couple of weeks ago , they are ready before others. 🙏🏻🙏🏻❤❤
Ctd25) Australia finds 2 cases which flew in from Africa .

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with R p shah memorial trust against Covid &for kids

R p shah memorial trust against Covid &for kids Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @Rpshahmemorial1

26 Nov
Long thread 1) There is this fear about the new Botswana/ Nu/ B1.1.159 variant but let's delve into why is this fear?? The 4 cases they found in Botswana were all vaccinated.So what??Breakthrough happens all the time,we underestimate incidence @hjelle_brian ctd)
Ctd2) This variant marked in blue is coming up , so what?? These variants will come and go. Ist it was the Wuhan strain in Grey , then the Beta ( SA strain in Green , then the Delta in Red and now may be the Botswana variant in Blue ( B1.1.529) @MoHFW_INDIA, @mansukhmandviya ctd)
Ctd3) For the virus and also the vaccines ( Pfizer/ Moderna/ AZ) the spike protein is the most important and that is where the maximum risk is . The Delta had 2 changes in spike proteins Receptor Binding Domain, the Beta had 3 while the Nu has 10 , so there is a real risk ctd)
Read 35 tweets
25 Nov
Long Thread - With the new variants one from Botswana and the Second #C13 from South Africa , I am reminded of an old post @hjelle_brian ,@DrEricDing
For a variant to win against the Delta means a new Sumo wrestler is in town and that it has the potential ability to wipe out some of the herd immunity that we have achieved from the Delta .@PrinSciAdvGoI ,@narendramodi,@shekhar_mande ,@OfficeOf_MM

Ctd 3) Also the second variant of interest from Botswana is another one growing ,that means India should immediately stop flights from Africa and also again look at the travel hubs that have flights coming from Africa eg Dubai@HardeepSPuri,@JM_Scindia
Read 4 tweets
25 Nov
Long thread -As a Surgeon I am painfully aware how difficult it is for a surgeon to work with a new anesthesist,or to work with new assistants/get work done in a new set up or with new nurses,there is a critical element of camaraderie, the team works like an oiled machine ctd)
Ctd2) A gentle grunt here , a small nudge there , you extend your hand and the instrument is in ur hand these arent luxuries, they put the mind of everyone at ease and causes better results in CRUX situations. HOWEVER the pandemic has disrupted these synergies@HalfwayKnown ctd)
Ctd3) Nurses are leaving , doctors & nurses are falling sick, some dying and others suffering from Long Covid. You just cannot simply replace a team member and expect them to perform, it takes time for them to settle in @DustyEnfermera,@NursesOntario ,@NursesWhoVax ,@NurseTexas
Read 7 tweets
24 Nov
Long post ) It has been my sudden realization that even though we knew all along since last 1.5 yr plus that airplanes are the biggest source of transfer of new variants @JimRosenthal4 , @kprather88 but instead of doing more about trying to prevent in flight infection we ctd)
@JimRosenthal4 @kprather88 Ctd2) we continued our apathy towards the same . Masking is important BUT as I have always maintained it has to be N95 masks in flight , we know that for every person infected there is a chance to infect occupants until 2 rows before and behind, worser this is pre Delta info ctd)
Ctd3) The same hasn't been updated , the Canadians at least did make an effort to try finding this out but haven't seen anything since last 6 months .Also we need to lay down the rules of inflight contamination levels @DrAxelrod_WHO ,@WHO ,@WHOEMRO ,@WHOSEARO ,@DrRabiWHO ctd)
Read 6 tweets
16 Nov
Long thread -The JVC recommendations, Telegraph story and apathy from Govts across the world on Covid in kids has me seething with rage ,2014 report sciencedirect.com/science/articl… @LongCovidKids ,@LCKScotland, @bees_oz ,@chrischirp,@dgurdasani1 ,@LCKCanada,@LCKIreland ,@kidsCovidGamble
Ctd2) clearly from the paper 15 kids were lost to flu when we introduced Flu vaccines in kids across UK.And how many do we have now , over a hundred have already been lost forever, a hundred families will stay up on Christmas eve and mourn, Santa will not visit those homes ctd)
Ctd3) This year flu shots have been expanded across UK . Why ?? 1) Govt wants to reduce flu levels in population BUT doesnt want to reduce Covid cases ?? 2) Vaccines against flu save kids and society both Ain't the same be said about Covid Vaccines .@TigressEllie, @Tall_Paul_05
Read 5 tweets
16 Nov
Long thread but some background first - I am a Pediatric Orthopedic Surgeon and have treated kids with special needs for the last 15 years, my wife is a gynecologist @fogsiofficial ,@narendramodi , @PMOIndia, @mansukhmandviya ,@OfficeOf_MM , @PrinSciAdvGoI , @shekhar_mande ctd)
@fogsiofficial @narendramodi @PMOIndia @mansukhmandviya @OfficeOf_MM @PrinSciAdvGoI @shekhar_mande Ctd) @BhallaAjay26 , @MoHFW_INDIA,@drharshvardhan and we have for last 15 years ensured that the kids we treat have the best solutions across the world , the pandemic has brought a new challenges @LongCovidKids ,@LCKScotland , @LCKCanada,@LCKIreland ,@Bodalicious1,@UTc19LongHaul
Ctd3) This long term advocacy of the rights of children with special needs is not our hobby ,its a life long committment and passion for our team .ctd)
Read 8 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Thank you for your support!

Follow Us on Twitter!

:(