Will try and keep everyone posted on the new developments on Omicron , the last thread became too lengthy in a day .But this is the information we had on 25/ 26 Nov. Ctd
Ctd2) I believe that it has become imperative that we immediately start finding whether the combination of Merck's Molnupiravir &Pfizers Antiviral is effective against Omicron?? we have had reports of Molnupiravir dropping efficacy yesterday in full trial.@hjelle_brian ctd)
@hjelle_brian Ctd3) virologists consider that the virus is " stealing " parts of our RNA as @hjelle_brian, to me it seems that these are efforts of virus to get past Interferons which are our defence mechanism .We know that those with Anti Interferon antibodies have bad course #Omicron ctd)
Ctd5) With 15 positive from 110 tested , seems that the 600 will have close to 90 , I agree. THEN in addition there will be others who WILL CATCH IN QUARANTINE.
@UNAIDS_ESA@AfricaHealthFed@dgurdasani1 Ctd9) If I were in the place of Potus I would push for boosters as hard as I could along with mandates , the next set of vaccines are at least 3 months to go and #Omicron would still be
amenable to boosters, doesn't loom like complete immune escape reuters.com/business/healt…
Ctd 10) And that brings me to the proponents of Herd Immunity,those who have maintained that Herd Immunity has come since the last 6 months to a year need to remember that it hasn't @SunetraGupta . Only by means of vaccines have we been able to control
.collateralglobal.org/article/mini-l…
Ctd 11) Meanwhile England's chief medical officer Chris Whitty has said his "greatest worry" is whether people will accept fresh curbs on activities to tackle #Omicron he questioned whether "we could take people with us" if restrictions had to be imposed.#BetterPersuasion ctd)
Ctd11) Apparently at the moment the information is that the infected have 75% unvaccinated and 25% vaccinated group, even amongst the infected breakthrough cases the patients are less severe . 🤞🤞. Early information. @emilygraymd_mph ,@rubyslippahs,ctd)
Ctd15) In a lesson for most countries banning people on flights from 6 Nations India has cast the net wider, ensuring that all permutations and combinations that can be made are covered with RTPCR,also we accept #COVIDisAirborne@takesthecake2 ,@AirQ007,@CorsIAQ,@Dr2NisreenAlwan
Ctd16) The Czech Republic and Germany both find one suspected case each .Contact tracing for all travelers within the last 1 month should be undertaken if possible, throughout is going to be tough ,almost impossible to do .
Ctd17) Across the world people who have championed the cause of kids have been scoffed at during the pandemic, long Covid in kids has been undermined and deaths in kids have been tied to comorbid conditions.Apparently #Omicron is more in kids and young .
Ctd18) As I said earlier that #Omicron looks bad in the simulation experiments , there is also now " PseudoVirus" simulation that have been done wherein a dummy virus with spike protein changes has been checked against plasma of people who have been saved & post vaccinated ctd)
Ctd19)The simulation shows that #Omicron will probably escape natural immunity and vaccines BUT those vaccinated and infected once may escape #OmicronVariant
Ctd20) 2 In UK and 2 tentatively in India , looks like a movie being rerun after a year 😢😢
Ctd21) The problem of vaccine hesitancy is not only in SA , sadly it is rampant across African continent. reuters.com/business/healt…
Ctd22) Seems that the disease is causing exhaustion and profound weakness in young adults and kids , what happens in elderly is not known by this news report. telegraph.co.uk/global-health/…
Ctd23) Israel acts fast .Finds 7 suspected cases - 3 In community,3 from those who have travelled recently , acts on the premise that it is there across the globe ( agree 100% ). Enforces mandatory Quarantine. aljazeera.com/news/2021/11/2…
Ctd24) Israel reintroduces Phone tracking apps , these are the war games that they practised a couple of weeks ago , they are ready before others. 🙏🏻🙏🏻❤❤
Ctd25) Australia finds 2 cases which flew in from Africa .
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Long thread 1) There is this fear about the new Botswana/ Nu/ B1.1.159 variant but let's delve into why is this fear?? The 4 cases they found in Botswana were all vaccinated.So what??Breakthrough happens all the time,we underestimate incidence @hjelle_brian ctd)
Ctd2) This variant marked in blue is coming up , so what?? These variants will come and go. Ist it was the Wuhan strain in Grey , then the Beta ( SA strain in Green , then the Delta in Red and now may be the Botswana variant in Blue ( B1.1.529) @MoHFW_INDIA, @mansukhmandviya ctd)
Ctd3) For the virus and also the vaccines ( Pfizer/ Moderna/ AZ) the spike protein is the most important and that is where the maximum risk is . The Delta had 2 changes in spike proteins Receptor Binding Domain, the Beta had 3 while the Nu has 10 , so there is a real risk ctd)
Long Thread - With the new variants one from Botswana and the Second #C13 from South Africa , I am reminded of an old post @hjelle_brian ,@DrEricDing
For a variant to win against the Delta means a new Sumo wrestler is in town and that it has the potential ability to wipe out some of the herd immunity that we have achieved from the Delta .@PrinSciAdvGoI ,@narendramodi,@shekhar_mande ,@OfficeOf_MM
Ctd 3) Also the second variant of interest from Botswana is another one growing ,that means India should immediately stop flights from Africa and also again look at the travel hubs that have flights coming from Africa eg Dubai@HardeepSPuri,@JM_Scindia
Long thread -As a Surgeon I am painfully aware how difficult it is for a surgeon to work with a new anesthesist,or to work with new assistants/get work done in a new set up or with new nurses,there is a critical element of camaraderie, the team works like an oiled machine ctd)
Ctd2) A gentle grunt here , a small nudge there , you extend your hand and the instrument is in ur hand these arent luxuries, they put the mind of everyone at ease and causes better results in CRUX situations. HOWEVER the pandemic has disrupted these synergies@HalfwayKnown ctd)
Ctd3) Nurses are leaving , doctors & nurses are falling sick, some dying and others suffering from Long Covid. You just cannot simply replace a team member and expect them to perform, it takes time for them to settle in @DustyEnfermera,@NursesOntario ,@NursesWhoVax ,@NurseTexas
Long post ) It has been my sudden realization that even though we knew all along since last 1.5 yr plus that airplanes are the biggest source of transfer of new variants @JimRosenthal4 , @kprather88 but instead of doing more about trying to prevent in flight infection we ctd)
@JimRosenthal4@kprather88 Ctd2) we continued our apathy towards the same . Masking is important BUT as I have always maintained it has to be N95 masks in flight , we know that for every person infected there is a chance to infect occupants until 2 rows before and behind, worser this is pre Delta info ctd)
Ctd3) The same hasn't been updated , the Canadians at least did make an effort to try finding this out but haven't seen anything since last 6 months .Also we need to lay down the rules of inflight contamination levels @DrAxelrod_WHO ,@WHO ,@WHOEMRO ,@WHOSEARO ,@DrRabiWHO ctd)
Ctd2) clearly from the paper 15 kids were lost to flu when we introduced Flu vaccines in kids across UK.And how many do we have now , over a hundred have already been lost forever, a hundred families will stay up on Christmas eve and mourn, Santa will not visit those homes ctd)
Ctd3) This year flu shots have been expanded across UK . Why ?? 1) Govt wants to reduce flu levels in population BUT doesnt want to reduce Covid cases ?? 2) Vaccines against flu save kids and society both Ain't the same be said about Covid Vaccines .@TigressEllie, @Tall_Paul_05
Ctd3) This long term advocacy of the rights of children with special needs is not our hobby ,its a life long committment and passion for our team .ctd)