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Eric Topol Profile picture
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29 Nov, 4 tweets, 2 min read
This is actually a BIG deal and fully warranted, evidence based. Great to see!
Thanks @CDCgov @CDCDirector Image
Revised: Image
People are asking why not 3rd shots for age <18, i.e. teens?
There is no application yet from a vaccine manufacturer to FDA for age <18, so it can't be recommended yet. That will change soon......
Soon turned out to be minutes
washingtonpost.com/health/2021/11… Image

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More from @EricTopol

Eric Topol Profile picture
28 Nov
The US markedly lags many countries with boosters, in part because of poor messaging, and lack of priority to get *all* adults with fully restored vaccine effectiveness.
Would help vs Omicron, too. Boosters induce a striking increase in level & breadth of neutralizing antibodies.
Today's @washingtonpost editorial
"The [waning] phenomenon should compel all adults to get a booster shot."
Our editorial on boosters, @mtosterholm @PostOpinions
"Each day in the United States, the number of people with waning immunity greatly exceeds those who are getting newly vaccinated"
washingtonpost.com/opinions/2021/…
Read 4 tweets
Eric Topol Profile picture
26 Nov
The @WHO has named B.1.1.529 Omicron, a Variant of Concern [O, not Nu)
Here's their full statement, summary of data
who.int/news/item/26-1…
This is only the 5th Variant of Concern since the pandemic began: Alpha, Beta, Gamma, Delta, and now Omicron.
That it was not named as a Variant of Interest is interesting and raises concern ;-)
There have been thousands of uninteresting #SARSCoV2 variants
Read 5 tweets
Eric Topol Profile picture
24 Nov
Our oped on the big mistake @CDCgov on boosters: All adults, not just age 50 plus, need them. Here's why
@washingtonpost @mtosterholm
washingtonpost.com/opinions/2021/… @PostOpinions
Now is not the time to withhold a vital and validated means of boosting our efforts to contain the virus
Each day in the United States, the number of people with waning immunity greatly exceeds those who are getting newly vaccinated. Accordingly, rather than building our wall of population immunity, the United States is suffering attrition.
Read 4 tweets
Eric Topol Profile picture
24 Nov
The UK's path towards improvement as much of Europe is worsening
1. Boosters (3rd shots) are working, as seen by fewer hospital admissions among the age groups receiving them
ft.com/content/974487…
2. Infection-acquired immunity playing a role
3, Comparison with many countries throughout Europe experiencing a rapid rise in cases, patients requiring ICU admission and deaths
Read 4 tweets
Eric Topol Profile picture
23 Nov
Just published @ScienceMagazine
The remarkably tight correlation of neutralizing antibody levels with protection from an mRNA vaccine (@moderna_tx)
science.org/doi/10.1126/sc…
Titer/Vacccine efficacy
10/78%
100/91%
1000/96%
These are important data, fully concordant with 2 recent studies, reinforcing why boosters are essential and why it is likely that a 3rd dose will be long lasting (1 year or longer)
@LancetMicrobe all vaccines, all variants
thelancet.com/journals/lanmi…
A 25-50 fold increase in levels of neutralizing antibody of the booster (3rd dose) compared with the 2nd, and more rapidly generated
medrxiv.org/content/10.110…
Read 4 tweets
Eric Topol Profile picture
20 Nov
The United States is not taking its 5th major wave seriously.
In November, new cases have increased 30% starting from the high level of 70,000/day. With that hospitalizations and deaths are increasing again.
We haven't taken heed from Europe 4 times
theguardian.com/commentisfree/… /1
Our vaccination rate is dangerously low, putting >100 million Americans (40% of 331 M) who are not vaccinated vulnerable. Then there's another 40% who were highly 💉💉protected, but are now out 6 months out and that protection has waned /2
Instead of @CDCgov urging all people who've waned to get a 3rd shot, they deemed them "eligible." Only age 50+ "should" according to their recommendation. That is *not* what the data show and will further diminish our immunity wall /3
Read 8 tweets

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