1 of 6:

Gauteng #Omicron update - 8 December:

The load on hospitals is significantly lower compared to Delta, and with a peak imminent, hospitals will not be overloaded at all.

No restrictions are needed to help hospitals in any way.
2 of 6:

The total number of patients in hospital is well below the Delta wave.

Since a peak in hospital numbers is expected in 12-22 days, this variable is not a concern anymore.

data source: NICD
nicd.ac.za/diseases-a-z-i…
3 of 6:

The portion of hospital patients ending up in ICU is much lower (10%) compared to Delta (24%).

Considering that a significant portion of patients in hospital have not been infected before, or are not vaccinated, #Omicron must be significantly less virulent.
4 of 6:

The portion of hospital patients ending up on ventilators is even lower (3-4%) compared to Delta (10%).

Note that the ratios for Delta were similar for Beta and the wild type virus. #Omicron is the first variant with such a dramatic drop in disease severity.
5 of 6:

Thanks to @jburnmurdoch for also highlighting this signficant drop with #Omicron .

There are additional factors such as lower ages of admissions that also reduce disease severity, but age alone cannot explain the significant drop.

6 of 6:

Countries are quick to implement travel bans, but take months to lift them.

Every vulnerable person infected with Delta before Omicron has a higher mortality risk, even if fully vaccinated.

Since we have leaky vaccines, a certain level of infections are inevitable.

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More from @pieterstreicher

10 Dec
1 of 10:

Should the rest of the world fear #Omicron?

South Africa is experiencing a very mild wave with #Omicron. The hospitals are easily coping even though case levels in Gauteng will exceed Delta levels. South Africa currently only has light restrictions.
2 of 10:

Despite light restrictions it is expected that only 15-25% of the country will be infected with #Omicron.

The South African context is unique. 70% of the population have had Covid-19 already. Only 50% of the adult population is fully vaccinated.
3 of 10:

Scenario 1: #Omicron escapes vaccine and natural immunity to a significant extent.

In this scenario, everyone in South Africa would have been vulnerable to Omicron, so the low deaths could then only be ascribed to a significantly lower virulence of the Omicron itself.
Read 10 tweets
9 Dec
1 of 6:

Gauteng #Omicron update:

Cases in Gauteng are likely to peak between 12 and 20 December.

The growthrate in 7 day average cases is slowing down consistently. It was 5% per day in the last day, down from 28% per day 12 days ago.
2 of 6:

The total number of patients in hospital is well below the Delta wave.

Since a peak in hospital numbers is expected in 11-21 days, this variable is not a concern anymore.

data source: NICD
nicd.ac.za/diseases-a-z-i…
3 of 6:

As we look at more severe outcomes, the numbers are even lower. ICU beds track well below the Delta trajectory.

No restrictions are needed to help hospitals in any way.
Read 6 tweets
8 Dec
1 of 4:

8 December Gauteng #Omicron short term projections:

Cases, hospitalisations and ICU beds are all running below my projections.

Ventilated beds are slightly above.
2 of 4:

The method is simple.

1. Determine the daily growth rate during the exponential phase for all variables.
(cases 30%, hosp 12%)

2. Estimate when cases will peak based on an Rt extrapolation. Alternatively, fit a Gompertz curve to the case trajectory.
(12 Dec)
3 of 4.

3. Apply a consistent drop in growth rate from the point when growth is not exponential anymore to the point when Rt=1.0. (Alt. - Gompertz fit)

4. Add a suitable lag period for the hospital variables. I used 6 days for hospital and another 5 days for ICU/vent beds.
Read 5 tweets
7 Dec
1 of 6:

7 December Gauteng #Omicron update:

Cases might exceed the Delta peak. All other variables will be significantly lower.

South Africa only has light restrictions currently (a 4hr curfew from midnight). The vulnerable continue to take extra care.
2 of 6:

Total hospital beds could be less than half of Delta levels (4,500 vs 9,200).

The growth rate is a consistent 10-12% per day.

data source: NICD

nicd.ac.za/diseases-a-z-i…
3 of 6:

Looking at more severe outcomes the gap is even larger.

ICU beds are expected to grow at 10-12% per day during the exponential phase.

ICU beds might peak at less than 570, almost 3x lower compared to the Delta peak.
Read 7 tweets
6 Dec
1 of 6:

6 December Gauteng #Omicron update:

With only light restrictions in South Africa, the load on hospitals remain much lighter compared to Delta.

My expected peak range from 12-22 December might be too conservative.
2 of 6:

In the next 3 days, we should be able to a more accurate prediction for the peak.

Total hospital beds could be less than half of Delta levels (4,500 vs 9,200).
3 of 6:

Looking at more severe outcomes the gap is even larger.

ICU beds might peak at less than 570, almost 3x lower compared to the Delta peak.
Read 6 tweets
6 Dec
1 of 4:

#Omicron - Gauteng will peak around 16 December.

Follow this report on Rt by Louis Rossouw to guage when Tshwane and Gauteng are likely to peak.

unsupervised.online/static/covid-1…
2 of 4:

Extrapolating Rt for Tshwane gives a peak on 9 December (Rt = 1.0 on ~ 9 December).

The other regions in Gauteng should peak approximately 7 days later around 16 December.

Hospital variables should peak another 4-14 days later: 10-20 December.
3 of 4:

Total hospital and ICU beds will grow at 10-12% per day maximum.

The growth rate in hospital admissions lag cases by approximately 5 days (horisontal offset between dark brown and blue lines).
Read 4 tweets

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