COVID Update: Three groups of Americans will face Omicron in 3 very different ways.

Those who can
Those who can’t
And the biggest group— those who can but haven’t

1/
17% of Americans have gotten boosted, a dangerously low number with a virus which doesn’t respect prior infection or those with 1 or 2 doses. 2/
23% of Americans either aren’t eligible for boosters (17%) or eligible for the vaccine (6%).

That’s 75 million Americans who are basically counting on the rest of us to stay safe through no choice of their own. 3/
So what about the rest of us? 60% of Americans are eligible to be vaccinated & boosted but have either no shots (22%), one shot (11%) or 2 (27%). 4/
That’s 60% of the population not only not protecting themselves but by extension put 75 million people at risk at the same time. 5/
There are in fact many reasons why people may not have gotten boosted.

With things changing fast with Omicron not everyone is aware that 3 doses is now the new 2 doses.
Some lack access & time.
Others don’t see vaccination as a priority for their teenagers given lower risks. 6/
Still, many are choosing not to.

Omicron is much more dangerous in the US with 83% of the public succeptable infection particularly with a rate of spread 2-3x Delta.

The fact that 1/4 of that group can’t protect themselves should influence the other 1/2 to 3/4 to act. 7/
This information should also influence public policy.

The 75 million people without a choice ought to be a priority of policymakers when considering whether people should be required to be boosted to be at work, school, or other public settings. 8/
The millions on the front lines of health care, already short-staffed, are at greater risk of illness now as people flood into hospitals. Hospitalizations are rising in 42 states. Blink & it will be 50 w Omicron.

Our policy response should act to protect this group. 9/
There are reports of clusters of cases among health care workers in South Africa and they’re not sitting on Omicron on top of a depleting Delta like the US is. 10/
What should that policy response be?

Boosters— 3 doses should be the new vaccination standard
Workplaces, events & schools should require boosters
Tests should be made ubiquitous
Anti-vitals scaled cheaply
Masks & ventilation the norm 11/
People who view that as an assault on their freedom must be weighed against the many vulnerable people who have no choice in the matter.

Their rights to live, work & learn safely, are the ones that need protecting. /end

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More from @ASlavitt

18 Dec
COVID Update: A setback is a setback. And we’ve had 3 setbacks with vaccine testing this week.

But all of those setbacks remind me of how blessed we have been so far by science and the people who monitor safety.

1/
One setback, announced yesterday, is the change of position from the CDC on Johnson & Johnson’s vaccine. 2/
J&J’s vaccine was flagged and pulled from the market temporarily in the Spring when reports of several blood clotting issues arose.

Many criticized the decision for causing doubt & disruption of vaccines at a critical moment after it was ultimately put back on the market. 3/
Read 23 tweets
16 Dec
COVID Update: Omicron will peak in the US in the third wave in January according to a consensus of 10 scientists we interviewed. 1/
So far Omicron is doubling every 2-4 days, extraordinarily fast. People with prior infections or have been vaccinated but not boosted are right in the path of the spread.

This makes the spread 2-3x as fast as Delta. 2/
Even with a limited understanding of the severity of Omicron, it feels like this implies some concerning news and some better news (it’s all relative at this point😕). 3/
Read 21 tweets
13 Dec
COVID Update: Vaccine boosters appear to double the effectiveness of vaccines against Omicron.

But with only 14% of the country boosted, we should brace for a tough winter. 1/
Studies in the UK and SA are coming back with a consistent finding.

Prior Delta immunity is not preventing Omicron. Re infection rates are at least triple Delta.
2 Pfizer vaccines (presume same for Moderna) have a 30-40% efficacy against Omicron. 2/
Some good news. In both cases (prior immunity & 2 vaccines), studies are showing T cell response (our line of defense that prevents more severe illness in the lungs) continues to work against Omicron. 3/
Read 20 tweets
12 Dec
COVID Update: At a time when most scientists are concluding an additional mRNA vaccines is needed, a Republican senator wants to go the other direction.

His idea? Prior infection should count as immunity. 1/
Roger Marshall from Kansas thinks the country should officially recognize prior COVID infection as the equivalent of being vaccinated when considering a vaccine requirement.

He’s not alone but he’s wrong in so many ways. 2/
Roger also recently said this:

“The people that have thus far not gotten the vaccine are not going to do it until this White House acknowledges natural immunity.”

He’s calling for a sort of protest? Wut? 3/
Read 21 tweets
9 Dec
COVID Update: 2 weeks ago we said we would know a lot more about Omicron in 2 weeks.

I’ve rounded up the best scientific opinions to share a consensus. 1/
The bottom line-up front: We should expect a significant wave of COVID this weekend: likely a Delta + Omicron wave. 2/
The consensus view of Omicron is that it is NOT innately more contagious, but that it IS spreading much faster. 3/
Read 25 tweets
4 Dec
Here’s the explanation. Omicron will only spread as fast as there are people to infect.

So the Rt or spread will be lower if Omicron can’t outcompete Delta or if it finds large amounts of unvaccinated people, even with prior Delta infections (as it has in S Africa). 10/
It’s possible that this is what’s happening. Omicron could be spreading no faster than Delta but because prior infection slows Delta down but not Omicron, that creates a higher Rt. 11/
This means Omicron, at least in parts of the US with low vaccination rates, will likely be dominant over the next few months even if it is no fastero than Delta.

Again, we all pay for the bad choices any of us make. 12/
Read 11 tweets

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