This one found that whilst glycine, both alone and within a multivariate model, can estimate appetite response to both water and whey protein beverage consumption, a large proportion of variance in appetite response remains unexplained.
Most biomarkers, when assessed in isolation, were found to be poor predictors of appetite response, therefore they're likely of utility only in combination with Visual Analogue Scales (VAS) and energy intake (EI).
"our current study demonstrated that glycine was the most prominent biomarker of appetite response, investigated in a whey protein model in a cohort of women with overweight/obesity."
One of the most interesting things I found was that it seems to lend some support for the glucostatic hypothesis, at least under certain conditions.
"Our current study also demonstrated that glucose, alanine, and amylin are potential biomarkers of appetite response under specific conditions...
"...The depleting glucose supply in the circulation is associated with increased Hunger during the prolonged fasted state, in agreement with the 'glucostatic hypothesis'...
"...However, when there was dietary source of protein, circulating glucose was no longer a reliable postprandial biomarker of appetite."
Postprandial glycine as a biomarker of satiety: A dose-rising randomised control trial of whey protein in overweight women (open access)

doi.org/10.1016/j.appe…

#appetite #nutrition #diet

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Nick Krontiris

Nick Krontiris Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @nick_krontiris

20 Dec
This study evaluated the association between nutrient patterns with body fat and regional adiposity in middle-aged black South African men and women.
- "the plant-driven nutrient pattern is the most commonly consumed in South Africa. It is characterised by high factor loadings of magnesium, phosphorus, plant protein, carbohydrates, iron, B-vitamins and fibre...
"...Although the plant driven nutrient pattern was not significantly associated with total or regional fatness in the combined sample of men and women, we show for the first time that this nutrient pattern was associated with higher abdominal SAT in women but not men."
Read 10 tweets
20 Dec
This one suggests that the antithrombotic effect of weight loss is preserved in the postprandial state, irrespective of the weight loss intervention.
- "This is the first study exploring postprandial changes in FVII activation and thrombin formation as a potential harmful mechanism in individuals with obesity during weight loss."
- "The present study demonstrates a postprandial increase in FVIIa after high-fat meals during diet-induced weight loss and surgery-induced weight loss...
Read 6 tweets
20 Dec
Here's one more that shows that HOMA-IR is associated with albuminuria and renal function impairment, this time in individuals living in Southeast China.
"Our study has three main findings...
"...First, an increase in the prevalence of albuminuria and renal function impairment was associated with an increase in the HOMA-IR quartile in all men and women age >45 years...
Read 7 tweets
20 Dec
This one found higher leisure-time physical activity levels to be associated with a lower risk of cardiovascular disease in Chinese retired adults, with the benefit threshold for CVD prevention equivalent to 3 to 5 times the world health organization (WHO) recommended minimum.
- The WHO recommends every adult to maintain a minimum of 150 min of moderate-intensity or 75 min of vigorous-intensity activity per week, which is equivalent to 7.5 weekly metabolic equivalent of task-hours ([MET]-hours/week) of physical activity.
- Compared with participants reporting LTPA less than the recommended minimum of 7.5 MET-hours/week, a lower risk was seen for those with 3 to 5 times the recommended minimum (22.5–37.5 MET-hours/week) with no additional benefit when exceeding 5 times the recommended minimum.
Read 4 tweets
20 Dec
This one found that prolonged physiological and supraphysiological hyperinsulinemia can induce blunted acute insulin signaling, reduced insulin-stimulated glucose uptake, transcriptomic changes, and affect genes in insulin signaling pathways.
- "We demonstrated that prolonged physiological and supraphysiological hyperinsulinemia induced a reduction of AKT and ERK signaling and insulin-stimulated glucose uptake..."
- "Remarkably, while serum starvation partially reversed the effects of overnight hyperinsulinemia, much of the impaired acute insulin signaling and transcriptomic remodeling was sustained after 6 h of insulin withdrawal and serum starvation...
Read 6 tweets
20 Dec
This one suggests that performing around 1800 MET-min/week (i.e. 64 min/day of moderate PA) is an effective method to prevent some major degenerative diseases that affect quality of life in a large part of the population over 50 years.
"American adults who perform at least 150 MET-min/week of PA presented reduced odds for sarcopenia, those who perform 150–1800 MET-min/week had reduced odds for osteoarthritis, and those who perform more than 1800 MET-min/week had reduced odds for osteoporosis...
"...It seems to be indicating that performing around 1800 MET-min/week (i.e. 64 min/day of moderate PA) is an effective method to prevent some diseases that affect quality of life in a large part of the population over 50 years."
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(