This one found that whilst glycine, both alone and within a multivariate model, can estimate appetite response to both water and whey protein beverage consumption, a large proportion of variance in appetite response remains unexplained.
Most biomarkers, when assessed in isolation, were found to be poor predictors of appetite response, therefore they're likely of utility only in combination with Visual Analogue Scales (VAS) and energy intake (EI).
"our current study demonstrated that glycine was the most prominent biomarker of appetite response, investigated in a whey protein model in a cohort of women with overweight/obesity."
One of the most interesting things I found was that it seems to lend some support for the glucostatic hypothesis, at least under certain conditions.
"Our current study also demonstrated that glucose, alanine, and amylin are potential biomarkers of appetite response under specific conditions...
"...The depleting glucose supply in the circulation is associated with increased Hunger during the prolonged fasted state, in agreement with the 'glucostatic hypothesis'...
"...However, when there was dietary source of protein, circulating glucose was no longer a reliable postprandial biomarker of appetite."
Postprandial glycine as a biomarker of satiety: A dose-rising randomised control trial of whey protein in overweight women (open access)
doi.org/10.1016/j.appe…
#appetite #nutrition #diet
doi.org/10.1016/j.appe…
#appetite #nutrition #diet
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