On @TimesRadio with @MattChorley just now - who for some reason invited me on as an expert, didn't like it when I challenged his flawed narratives on SAGE modelling, and then never gave me a chance to respond - and hung up on me when challenged!
This is MSM- and they are very much responsible - as I said in my interview for putting out false narratives. I mean saying that modelling is flawed because we didn't have 200K predicted deaths in yr 1 of the pandemic is just lazy. We acted- we locked down in response to crises.
What do you think would've happened had we not? There has been a lot of uncertainty in SAGE modelling, which the modellers acknowledge clearly- and media often picks on one scenario to critique them. Not even acknowledging that action was taken in response.
The SAGE *best case* scenario now says double or triple the no. of hosp will happen despite plan B. The worst case scenario is much worse. SAGE has been honest about the uncertainty, but the truth is there is no good scenario.
I know some in media want to cast doubt on the modelling to normalise the crisis we're going into. But it will be a crisis. Don't be complicit. The public needs accurate information not hopium and copium. Do your job.
And if you invite experts the least you can do is let them respond, and not hang up on them. if you do know better, than why bother having experts on at all. And yes, don't bother contacting me again.
And has SAGE modelling always lined up with predictions- more often than not at least in the shorter term. Always? no. But that's the nature of modelling- things change, and you can't predict exact behaviour- which they always acknowledge.
But does that mean that the caution they advised at those points was wrong? No. Regardless of how summer ended up, keeping mask mandates would've prevented many deaths, and a lot of long COVID. Uncertainty in modelling doesn't mean uncertainty in policy.

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More from @dgurdasani1

22 Dec
A thread slightly borne out of frustration on the widely misrepresented discourse on long COVID, esp in children. This is for the 'long COVID studies in children with controls are rigorous and loads of controls have symptoms so not sure this syndrome is real or important' group🧵
First, controls per se *do not* make a study sound - How do you account for the fact that children are often asymptomatic acutely, serorevert quickly or don't seroconvert at all. Long COVID itself is associated with lower Ab levels, furthering this bias.
Rigorous science is v. important, but let's not pretend that studies are rigorous because they have controls (just like people pretend RCTs are superior to observational evidence by virtue of being RCTs, even if they're conducted badly).
pubmed.ncbi.nlm.nih.gov/34273064/
Read 31 tweets
21 Dec
An important study- it suggests that Omicron has a much greater growth advantage among the vaccinated, and previously infected, and possibly a lower growth advantage compared to delta among those who were susceptible (not vaccinated/infected or waning of immunity)
This doesn't mean vaccines are not effective. It means that among the vaccinated and previously infected, omicron has a higher advantage compared to delta because it has higher escape from immunity (although both have lower infective probability compared to unvaccinated)
It's possible that intrinsic transmissibility of omicron relative to delta (apart from escape) may not be much higher, or possibly even slightly lower. But it would still have a massive advantage among those with prior immunity through vaccines/infection.
Read 10 tweets
21 Dec
I honestly cannot believe that we're living in a country where our govt is acting against scientific advice once again, and delaying action on rapid exponential growth, fully aware of the consequences- for the fourth time- a stance normalised by a complicit media.🧵
With a rapidly growing new variant doubling every 2 days, increasing hospitalisations already in London, which is ahead in terms of spread. The lags between infection and hospitalisation haven't happened yet, so this situation will only get worse.
We're seeing the highest hospitalisation rates with COVID-19 we've ever seen in 0-5 year olds, and rising.
Read 19 tweets
20 Dec
Wrong. SPI-M-O modelling has a lot of uncertainty because of many unknowns which are clearly acknowledged. Saying we didn't have 200K deaths last yr (um... because govt responded with lockdowns!) is disingenous & misleading.🧵
SAGE modelling has predicted outcomes within their range of uncertainty more often than not. And they're very clear about the uncertainties. If you don't know this perhaps try listening to experts who have followed it closely.
Even where the predictions haven't been exactly in the range, the general direction of movement, and policies advocated for have been sound. E.g. not removing mask mandates over summer would've saved lives and prevented a lot of long COVID even if cases didn't reach massive highs
Read 7 tweets
19 Dec
If you want to know what it's like being a Brown female scientist, this tweet captures what I deal with every day. Despite having called most things right & advocated for early response to protect public health and lives, time & time again, I'm attacked & abused. 🧵
Very few people know, let alone understand, what it's like being an outspoken woman of colour in academia. If you want to know I'd recommend talking to some. It hurts. Every day.
I've been outspoken and challenged injustice all through my career, from medical school to now. I've suffered *hugely* as a result.
Those who've known me for a while will know that I was dismissed from the @sangerinstitute after whistleblowing.
Read 26 tweets
19 Dec
@MerylSwanLake @mugecevik @kallmemeg I don't really want to relive it by pulling out the tweets, but Muge has said that I'm such a bad example of scicomm that she would use me in her teaching. Meaghan has said I get paid by the Citizens for what i do which is why I have loads of time to write BMJ pieces etc.
@MerylSwanLake @mugecevik @kallmemeg She never apologised despite this being wrong and slanderous. When I contacted a HT in a school with an outbreak to understand the process for reporting outbreaks, she also said I had breached data protection guidelines, and was akin to HIV research where patients are identified.
@MerylSwanLake @mugecevik @kallmemeg I actually headed up the UK HIV genomics consortium, and ethical issues around this are very serious, and I honestly cannot believe someone would ever say something like this- it's insulting, offensive, in so many ways.
Read 5 tweets

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