#MerryChristmas2021! If I had one wish from #SantaClaus, what would it be?
With the #OmicronVariant, there’s a lot of chat on what countries should do with #COVID_19 vaccinations – start boosters or complete the first round of the recommended two doses for everyone? If boosters, should it be for all, or select populations? My take.
As a global community, there is no question what we should do – work towards #VaccineEquity, and make sure that every eligible human gets their two doses. Remember, none of us are safe, unless all of us are safe. Cliched, but true.
The world, especially high income countries, need to make sure that they support #LMICs with their vaccinations. We have failed abysmally in this effort, and a lot of the blame rests with the global west, who have even allowed millions of doses to expire
When it comes to the question of boosters vs ensuring that people get their two mandatory doses first, it comes down to availability of the vaccine. If adequate vaccines are available, people should get a booster – there is enough evidence to support this. But...
But the truth is – there aren’t enough vaccines globally to make sure everyone gets at least two doses. There are countries where even healthcare workers haven’t been fully vaccinated; where less than 10% have got even one dose. We just can't ignore these realities
In most African countries, we should undoubtedly prioritize the first two doses – this will protect the African population (which by itself should be enough reason) but also protect the rest of the world. The rest of the world needs Africa to get the vaccines!
What should countries like the US, Europe, and even India do? Where we have plateaued with our first two doses, and at least with US and Europe, we’re seeing a major spike in cases?
I still think that in global interest (and even our own selfish interests), we should prioritize people who haven’t had their first two doses, both within our own countries, and those like Africa which hasn’t had much support from the rest of the world.
The recent announcement from @SerumInstIndia that they were scaling down production is disturbing – for many reasons. When the world is struggling to get enough doses, this is tragic.
We should work towards ensuring that every manufacturing facility does so at its maximum capacity, not scale down because there is not enough demand.
In an ideal world, every manufacturing facility should go full speed on quality COVID_19 vaccines, and supply the world, as if it was one big village. Prioritizing Ethiopia, Senegal, Tanzania, Sudan, Burkina Faso, as if they were our own
Knowing the frailties of humans and the world’s political leadership, they should at least work towards fulfilling their own countries’ requirements, and send the surplus to the rest of the world which needs it desperately. This is a true test of global health equity
I do understand that this may not resonate with many, given that self-protection comes first, but let us realize that we are being foolish if we think we can beat COVID_19 by merely protecting our own people.
#VaccineInequity is the biggest problem facing the world today, and we need to do everything that we can to address this.
But will the world’s leaders demonstrate true leadership? We need true leadership now more than ever. If ever we need #SantaClaus, it is now.

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More from @cspramesh

9 Oct
A couple of days back saw the inauguration ceremony of "Asha Nivas" at @ACTREC_TMC by Hon'ble CM of Maharashtra @OfficeofUT @CMOMaharashtra and @sudhamurty in the presence of Shri K N Vyas @DAEIndia and Prof R A Badwe, Director, Tata Memorial Centre. Why is this such a big deal?
Let me explain-Asha Nivas is a place where patients treated at @TataMemorial and @ACTREC_TMC can stay during their cancer treatment. Consider that 86% of patients being treated by us come from outside Mumbai, 60% from outside Maharashtra, 65% hailing from low socioeconomic strata
Costs of living in a city like Mumbai can often be a bigger deterrent than costs of cancer treatment, with the result that many patients even with curable cancers abandon their treatment. Providing them with a convenient, hygienic and safe place to stay is important
Read 6 tweets
24 Jul
This is such an important concept to understand. Very often, the public & even a lot of physicians equate the success of a screening test to detecting cancers early when patients are asymptomatic / improved survival amongst those detected to have cancer. This is inherently flawed
Why are early detection & improved survival not sufficient to proclaim success of a screening test?
While it seems intuitive, these two do not actually translate into lives saved
This doesn't seem logical, but it's true
This is because all cancers are not lethal, and merely detecting a cancer earlier than it would otherwise have been detected does not necessarily mean improved outcomes. To understand this, we need to understand three important biases inherent to screening studies
Read 14 tweets
11 Jul
A group led by @drsabita & @docpriyar set out to look at the impact of COVID_19 on physicians in India from a gender perspective, our hypothesis being that a greater burden of familial/domestic responsibilities fell on women. Full paper: ascopubs.org/doi/pdf/10.120… 1/n
The #COVID_19 pandemic had realigned our lives, and for many, especially in healthcare, increased their work considerably. Healthcare workers globally found themselves working overtime to handle the pandemic, while their domestic work increased thanks to the lockdown 2/n
This survey of over a 1000 Indian physicians confirmed our fears that the burden of running the family and domestic chores were indeed disproportionately handled by women. While this was not completely unexpected, the magnitude of the inequity was striking 3/n
Read 9 tweets
3 Jul
#SARSCov_2 viral variants / mutants and vaccination seem to be consuming most discussions on #COVID_19 these days. We’ve let incomplete data and general knowledge create misinformation and confusion amongst us all. An explanatory thread...
We’ve heard of the #Delta, the #DeltaPlus & unknown future variants which may be either more transmissible or more lethal than previous ones. This has either created panic, or worse, a sense of futility about both vaccines and precautionary measures to avoid the infection
The chatter about variants and mutants is fascinating, but linking them to the futility of getting over this pandemic is dangerous. An unfortunate line of thought seems to be that if these viruses mutate and vaccines are ineffective against them, why bother getting vaccinated?
Read 12 tweets
26 Jun
The worst of the second wave of #COVID_19 seems to be behind us in India. Here are some random thoughts…
Let’s face it – the second wave caught all of us by surprise by the sheer ferocity with which it unleashed itself. The inadequacies and frailties of our healthcare systems lay exposed. After nearly three months of helplessness, we are limping back to some semblance of control.
The key for our immediate future and that of our children is how we handle the next few months. For starters, we are not yet out of the woods with the second wave
Read 12 tweets
5 Jun
We had some interesting findings from our study on the impact of COVID-19 on cancer care. What we did was pretty simple…

Impact of COVID-19 on cancer care in India: a cohort study thelancet.com/journals/lanon…
We looked at volumes of services in 41 cancer centres that were part of the @CancerGridIndia over a 3 month period during the pandemic in 2020 and the same 3 months in 2019.
These 41 centres treat exactly one-third of all patients with cancer in India – approximately 450,000 new patients every year. So, our study was fairly representative of what was happening in the country (and probably many other parts of the world)
Read 14 tweets

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