The worst of the second wave of #COVID_19 seems to be behind us in India. Here are some random thoughts…
Let’s face it – the second wave caught all of us by surprise by the sheer ferocity with which it unleashed itself. The inadequacies and frailties of our healthcare systems lay exposed. After nearly three months of helplessness, we are limping back to some semblance of control.
The key for our immediate future and that of our children is how we handle the next few months. For starters, we are not yet out of the woods with the second wave
While 50,000 new cases/day seems low compared to >400,000 in May, it is still >50% of the first wave’s peak; and with >1300 deaths a day, we are higher than the peak of the first wave
We’re not short of predictions from various sources about how this will pan out, but let me emphasize that at worst, these are astrology, and even at best, these are all predictions - all based on numerous random assumptions, highly fraught with the likelihood of being inaccurate
We’ve had projections that the next wave will hit children the most, some which say that it will be milder while some predict a worse wave than the second. As we’ve learnt over the last 18 months, these predictions are rarely right
They are rarely right not because scientists making these projections are frauds, but because they are based on too many assumptions, and relying entirely on these is unwise. So what can we do now? Rather than futile attempts at prediction, prevention and preparedness are key
By preparedness, we need to be nimble in our responses to daily (and often hourly) changes in the way the pandemic has behaved. We need to ensure that we don’t suffer from the problems we had with the second wave – oxygen, hospital beds, and avoiding non-evidence-based treatment
We need open, transparent data so that we plan our responses & divert resources to regions that need them the most. The 2nd wave has brought in a lot of resources & rapid ways of transferring them to those most at need. But we need reliable data to guide this effort
But the bottomline still remains efforts at breaking the chain – prevention of transmission. What we are seeing on the streets is pandemic fatigue and carelessness – no masks, or incorrectly worn masks, no physical distancing. This could have disastrous consequences
At the risk of offending several groups, let me emphasize that COVID appropriate behaviour should be agnostic of any religious, social or political leanings. #SARSCoV2 respects none of these.
However frustrated and fatigued we are with #COVID_19, we just can’t let our guard down.
And here, I’m afraid there are no magic bullets. It’s back to the basics – the 3+1 Ws – Wear a mask, Watch your distance, Wash your hands, and (with some poetic license) Waccinate yourselves

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More from @cspramesh

5 Jun
We had some interesting findings from our study on the impact of COVID-19 on cancer care. What we did was pretty simple…

Impact of COVID-19 on cancer care in India: a cohort study thelancet.com/journals/lanon…
We looked at volumes of services in 41 cancer centres that were part of the @CancerGridIndia over a 3 month period during the pandemic in 2020 and the same 3 months in 2019.
These 41 centres treat exactly one-third of all patients with cancer in India – approximately 450,000 new patients every year. So, our study was fairly representative of what was happening in the country (and probably many other parts of the world)
Read 14 tweets
26 May
There has been a lot of panic in India about the “black fungus” which has caused substantial concern, morbidity and even deaths in patients with COVID. This is a short thread to explain what we know about it Image
The truth is that we don’t know everything about it, but let’s start by calling it what it is – “Mucor”. And anybody who claims that they know all about it is hmm…., let's say, “factually incorrect”
First, how does mucor spread & how do patients with #COVID-19 get infected with it? Mucor is a fungal infection caused by “mucormycetes”, a group of fungi. These fungi are ubiquitous – in soil, fallen leaves, compost, and air. Yet, most of us don’t develop the disease Image
Read 20 tweets
15 May
This thread is directed to all of you searching for plasma donors and/or amplifying requests for plasma donation, but most importantly, for physicians suggesting plasma donation, or patients’ families demanding #ConvalescentPlasma treatment for their loved ones.
Over the past year and more, we have had #ConvalescentPlasma dominating conversations about #COVID_19 treatment. Families have run from pillar to post trying to find a compatible donor. We’ve had celebrities urging people to donate.
Importantly, we’ve had heartbroken families feel guilty about not having been able to identify a suitable donor in time to save their loved one’s life. This thread is meant for all of them.
Read 17 tweets
13 May
Today, our usual "Thursday morning meeting" at @TataMemorial was anything other than usual...
0.4%. This number becomes significant in the last tweet of this thread.
Follow on.
The topic for today's meeting was "How have nurses contributed to the @TataMemorial #COVID_19 response? This was planned to coincide with the #InternationalNursesDay2021 and the #InternationalNursesWeek
Our very unassuming Deputy Nursing Superintendent made the presentation. For the next 25 minutes, the audience was spellbound. She described how the nurses helped @TataMemorial handle the pandemic over the past 15 months.
Read 12 tweets
18 Apr
I know the #COVID-19 numbers in India are not looking good, but here are my (not so) random thoughts on it Image
We have 2 options – one, rant & rail against the ‘system’ and lament how it has let us down; second, do whatever we can to avoid getting infected & if infected, minimize adverse consequences to ourselves & others. If you belong to the first, you can stop reading now
How can we avoid getting infected? There’s no magic bullet, I’m afraid. This is primarily a “stick to the basics” approach. More difficult than it sounds.
Read 25 tweets
8 Apr
Why is there a shortage of Remdesivir, with family members desperately trying to procure it when it has been proven that it is no better than routine care? #EvidenceBasedMedicine
There are two living meta analysis and systematic reviews that show it is not better than routine care. Close to 4000 patients in randomized trials showing no benefit, and patients & families desperate and buying in the black market because they believe it will save their patient
Wow! This tweet seems to have stirred up a lot of interest (and violent reactions). I'm glad there has been (some) discussion about the science, and the evidence, and justifiable disagreement. We've had experienced experts in the field weighing in, and I respect those views
Read 19 tweets

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