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Chise 🧬🧫🦠💉

@sailorrooscout

3 Jan

A CWRU School of Medicine study of 577,938 pediatric and adult patients shows first time SARS-CoV-2 infections occurring at a time when Omicron was rapidly spreading were associated with significantly less severe outcomes than first time infections when Delta predominated. 🧵

It is IMPORTANT to note severity of disease in humans is NOT determined only by virus replication but also by the host immune response to the infection. Make sure you are PROTECTED. Source for the information above can be found here: medrxiv.org/content/10.110… PLEASE NOTE.

Currently, data on the severity of the disease caused by the Omicron variant compared with the Delta variant has been limited. Here, researchers compared 3-day risks of emergency department (ED) visit, hospitalization, intensive care unit (ICU) admission, & mechanical ventilation

Read 15 tweets

Chise 🧬🧫🦠💉

@sailorrooscout

2 Jan

“Breakthrough” infections DO NOT mean vaccines don’t work. Remember, they are preventives, NOT cures. One can still contract COVID once vaccinated. As long as that vaccine is preventing you from facing severe disease and worse, it IS working and doing what it was designed to do.

The term infection refers to the virus entering and being detectable in your system regardless of whether OR NOT it makes you sick, whereas the term illness refers to the virus entering, being detectable in your system AND making you sick. It it important not to conflate the two.

The first thing to know about the COVID-19 vaccines is that they’re doing exactly what they were designed and authorized to do. Since the vaccines first started their rollout late last year, rates of COVID-19 disease have taken an unprecedented plunge among the immunized.

Read 12 tweets

Chise 🧬🧫🦠💉

@sailorrooscout

31 Dec 21

Encouraging news out of South Africa. Study data has suggested South Africa’s Omicron peak has indeed passed with NO major spike in deaths OR hospitalizations.

The study looked at the rate at which the fourth surge in cases progressed in the South African city of Tshwane, which researchers described as the "global epicentre" of the Omicron wave.

Researchers looked at hospital records from a Tshwane hospital system and compared them to prior surges. Based on their analysis, the omicron wave "spread and declined in the City of Tshwane with unprecedented speed peaking within 4 weeks of its commencement."

Read 7 tweets

Chise 🧬🧫🦠💉

@sailorrooscout

30 Dec 21

Them: Is there any other vaccine in history that required three doses in a year and yet still didn’t prevent transmission of the virus it was meant to protect against?

Me: Your childhood vaccinations would like a word with you.

Before I forget, reminder that your TDap: Tetanus-Diphtheria-Pertussis (every 10 years) are technically a repetitive vaccine series or rather boosters during adulthood. HPV is another vaccine that could fit here as well.

“Even the measles vaccine, which is incredibly effective, fails to protect about 3% of vaccinated individuals who are exposed to the virus. Jonas Salk's polio vaccine-hailed a medical miracle- was 80% to 90% effective at preventing paralysis caused by the polio virus.”

Read 4 tweets

Chise 🧬🧫🦠💉

@sailorrooscout

30 Dec 21

Immunity is more than just neutralizing antibodies.

Why? Because MOST of your T-cell responses from vaccination or previous infection STILL recognize Omicron.

Let’s talk about that!🧵

Immunological memory consists of antibodies, memory B-cells, memory CD8+ T-cells, and memory CD4+ T-cells. These responses are what give us enduring protection even against newly emerging SARS-CoV-2 variants.

Immunological memory is probably the most important feature of immunity as it allows us to better respond when the threat is encountered a second time. Against SARS-CoV-2, it helps to determine protection against reinfection, disease risk, and vaccine efficacy.

Read 14 tweets

Chise 🧬🧫🦠💉

@sailorrooscout

28 Dec 21

A new study shows Omicron infection ENHANCES neutralizing immunity against Delta, ESPECIALLY in those who are vaccinated, suggesting that Omicron will help push Delta out, as it should DECREASE likelihood that someone infected with Omicron will get re-infected with Delta. 🧵

https://twitter.com/sigallab/status/1475584463941914635?s=21

Source for the information above can be found here:
•secureservercdn.net/50.62.198.70/1…
•

https://twitter.com/sigallab/status/1475584463941914635?s=21

Researchers enrolled both previously vaccinated and unvaccinated individuals who were infected with SARS-CoV-2 in the Omicron infection wave in South Africa soon after symptom onset. They then measured their ability to neutralize both Omicron and Delta virus at enrollment versus

Read 8 tweets

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