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Sputnik V Profile picture
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4 Jan, 3 tweets, 3 min read
Canadian real-world study of mRNA vaccines efficiency vs #Omicron shows negative efficacy of 2 mRNA doses and quickly waning efficiency of homologous #mRNA booster: “A third dose provides some protection in the immediate term, but substantially less than against #Delta.”
Study of mRNA vaccines real-world efficiency shows two shots are not protective against #Omicron, #mRNAs ineffective as #boosters:
“Vaccine effectiveness against Omicron was 37% ≥7 days after receiving an mRNA vaccine for the 3rd dose.”

medrxiv.org/content/10.110…
New study supports earlier findings from Denmark showing “no significant protection against #Omicron infection beyond 31 days after the second dose of BNT162b’’ with significant negative efficacy 91-150 days after the second #Pfizer dose.
👇
medrxiv.org/content/10.110…

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More from @sputnikvaccine

Sputnik V Profile picture
3 Jan
In recognition of quickly waning Pfizer vaccine efficacy US FDA recommends reducing interval for Pfizer booster shot from 6 months to 5 months. Instead, booster by other vaccines is needed to lengthen Pfizer vaccine protection particularly against #Omicron
Read 5 tweets
Sputnik V Profile picture
30 Dec 21
Gamaleya Institute: “Russian Ministry of Health recommends Sputnik Light booster 6 months after vaccination to increase protection against #Omicron and other mutations.” Sputnik vaccines showed high level of virus neutralizing antibodies and T cells against #Omicron Image
Sputnik Light is a universal booster to other vaccines for fastest, strongest and longest protection against #Omicron and other mutations.
👇
indiamedtoday.com/sputnik-v-indu…
Read 6 tweets
Sputnik V Profile picture
28 Dec 21
1/4 Sputnik team has been the 1st to raise issue with quickly dropping efficacy of mRNA vaccines and relentlessly offered cooperation through mix&match/combo vaccine approach that works better against emerging mutations such as #Omicron and #Delta.

2/4 On September 17, 2021 we suggested that Sputnik Light booster will help Pfizer vaccine last longer.
3/4 We even offered to help “dress the Emperor up”

Read 4 tweets
Sputnik V Profile picture
28 Dec 21
5 studies on quickly waning mRNA vaccines that make countries cut mRNA boosters time to 3 months/introduce 4th mRNA booster

Boosting by other jabs will prolong mRNA immune response

@JAMA_current: mRNA efficacy vs #Delta among elderly 20% after 4 months👇jamanetwork.com/journals/jaman…
2/5 According to Swedish data Pfizer vaccine’s efficacy against #Delta COVID strain is falling to below 30% after 6 months.
👇
papers.ssrn.com/sol3/papers.cf…
3/5 The UK Health Security Agency said those who had received three doses of Pfizer’s vaccine saw their protection against symptomatic illness caused by #Omicron variant drop to 45 percent within 10 weeks.
👇
gov.uk/government/pub…
Read 5 tweets
Sputnik V Profile picture
17 Dec 21
1/5 BREAKING: #SputnikV induces robust neutralizing antibody response to #Omicron, further strengthened by Sputnik Light booster, performing 3-7x better than other (including mRNA) vaccines. Light’s efficacy vs Omicron expected ~80% after 2-3 months.
👇
sputnikvaccine.com/newsroom/press…
2/5 Vaccines virus neutralization decrease against #Omicron:

Pfizer: 41x
Moderna: 49-84x
Sputnik V: 11.8x

Sputnik’s showed 3-7x less of a reduction than mRNA vaccines.
3/5 Virus neutralizing activity against #Omicron 2-3 months after Sputnik Light booster is higher than VNA vs “wild-type” virus 6 months after Sputnik V vaccination. Based on these data expected efficacy of Sputnik Light as a booster against Omicron could be more than 80%.
Read 5 tweets
Sputnik V Profile picture
20 Oct 21
New study by Honduras' @UNAHoficial showed #SputnikV & Moderna or Pfizer combo is effective & safe.
It proves the success of mix&match approach, pioneered by #SputnikV. 1-shot Sputnik Light is ideal booster for mRNA, whose efficacy falls to below 50% 5 months after vaccination.
UNAH study found that combinations’ immune response exceeded that achieved with conventional homologous schemes.
Sputnik was world’s 1st vaccine cocktail, pioneered mix&match with other vaccines & offered 1-shot Sputnik Light as booster.
Sputnik V made an offer to Pfizer to start trial with Sputnik Light as booster on August 11, 2021.

Read 4 tweets

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