"Last week, the highest number of #COVID19 cases were reported so far in the pandemic - and we know for certain that this is an underestimate”, says @DrTedros in WHO presser.
While Omicron appears less severe than delta, that does not make it “mild”, he says.
@DrTedros "Just like previous variants Omicron is hospitalizing people and it's killing people”, says @drtedros.
"In fact, the tsunami of cases is so huge and quick that it is overwhelming health systems around the world. Hospitals are becoming overcrowded and understaffed."
@DrTedros “First-generation vaccines may not stop all infections and transmission, but they remain highly effective in reducing hospitalization and death from this virus”, says @drtedros.
That is why other measures are needed too, he says.
@DrTedros "Vaccine inequity and health inequity overall were the biggest failures of last year”, says @drtedros.
"At the current pace of vaccine rollout 109 countries would miss out on fully vaccinating 70% of their populations by the start of July 2022."
@DrTedros "The essence of the disparity is that some countries are moving toward vaccinating citizens a fourth time while others haven't even had enough regular supply to vaccinate their health workers and those at most risk”, says @DrTedros.
@DrTedros Also talks about humanitarian crises, pointing out that WHO has not been permitted to deliver medical supplies in Tigray region since mid-July last year.
“The de facto blockade is preventing access to humanitarian supplies, which is killing people."
@DrTedros "I've spent a couple of days outside of the office during this holiday period and I'm struck by how people actually are wearing masks”, says @mvankerkhove. “Wearing a mask below your nose wearing a mask off of your ear wearing a mask below your chin is useless..."
@DrTedros @mvankerkhove Obligatory question about #B16402.
Was discussed and made variant under monitoring in November, @mvankerkhove points out.
"Our understanding: it's not very well circulating within France. Less than 1% of the samples that were sequenced in France are of this particular variant."

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More from @kakape

30 Dec 21
One of the complexities in talking about #omicron is that we are constantly talking about the variant’s properties on two levels:
in a naive population and in an immune population (in reality many populations with different levels of immunity)
That matters.
Take transmissibility:
It’s been clear from watching #omicron that it spreads faster than delta.
But from the beginning the question has been: Is that because it can infect people delta can’t? Or is it inherently more transmissible?
If you look at the UK’s risk assessment of #omicron for instance, you can see that that question is still not settled:
"there is no clear epidemiological demonstration of transmissibility as distinct from other contributors to growth advantage”
assets.publishing.service.gov.uk/government/upl…
Read 12 tweets
29 Dec 21
Three things were always needed to beat #SARSCoV2: science, solutions and solidarity, says @DrTedros at @WHO presser.
"Science to both understand the pathogen and find solutions to beating it and solidarity to share and deliver those tools wisely and equitably."
@DrTedros @WHO “While science delivered, politics too often triumphed over solidarity”, says @drtedros.
“Populism, narrow nationalism and hoarding of health tools, including masks, therapeutics, diagnostics and vaccines by a small number of countries undermined equity"
@DrTedros @WHO “Misinformation and disinformation, often spread by a small number of people, have been a constant distraction, undermining science and trust in life saving health tools”, says @drtedros.
Read 10 tweets
28 Dec 21
“I didn’t anticipate the havoc polarized politics would wreak on a pandemic response.”

This is a great look back by @HelenBranswell teasing out some pretty grim lessons from the complete dumpster fire of these last two years

statnews.com/2021/12/28/10-…
“For reasons I may never understand, in January and February of 2020 much of the world seemed not to grasp that the new virus that was spreading so rapidly in China wouldn’t stay in China.”
I feel the exact same way. Hard to imagine I will ever quite understand this…
And remember this in the coming weeks:
“The guiding principle of outbreak response is hope for the best but prepare for the worst. It has felt too often in this pandemic that people are forgetting about the second part of that maxim.”
Read 4 tweets
24 Dec 21
One month ago, I wrote a first thread on #omicron (before it was called that) and I said we needed patience and we would learn a lot more.
So where are we today?
A quick #omicron thread before I sign off for a few days:

WHAT WE HAVE LEARNED:
A lot of the early fears have been borne out.
The virus is spreading in many countries just as it did in SAfrica.
It clearly has a huge growth advantage over Delta.
It is a lot better at infecting vaccinated and recovered individuals than previous variants.
BUT:
As the virus has spread, we have seen some hopeful signs as well.
We have seen fewer hospitalisations so far than in previous waves.
We have seen a faster than expected turnaround in South Africa.
We have early data suggesting the virus *might* be inherently milder.
Read 15 tweets
22 Dec 21
Interesting early data on #omicron severity in this preprint from SAfrica.

Main take-away for me still:
Population with high protection from severe disease but low protection from infection means more infections with mild symptoms.
Inherently milder? 🤷‍♂️

medrxiv.org/content/10.110…
The authors compared SGTF cases with non-SGTF cases during the same time period (1/10 - 30/11).

Remember: SGTF is S gene target failure, the signal in certain PCR tests that is currently used as an (imperfect) proxy for omicron infections.
The authors found that the risk of these likely #omicron cases to end up in hospital was only about one fifth the risk (10-30%) of cases without SGTF (likely not omicron)
But once patients were in hospital, their risk of severe disease was about the same.
Read 9 tweets
21 Dec 21
"We are clearly in a new and troubling phase of this pandemic. What we have seen so far is sobering but there is still much to learn about Omicron. We cannot afford to cross our fingers and hope this crisis blows over”, @JeremyFarrar writes in a statement just out.
@JeremyFarrar If transmission isn’t slowed, "we could see profound impacts on health systems but also across sectors such as education, hospitality, public transport, police and essential national infrastructure as infections prevent people from working.".
@JeremyFarrar It's "staggering and deeply frustrating that two years into this pandemic – when we have gathered so much evidence and made huge scientific progress – that governments are still not anticipating events and acting early or working together anywhere near the scale that is required"
Read 5 tweets

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