The more you understand, the less you need to memorize. Take this 🫀 example:

Severe AR and MR are both defined by a regurgitant volume of 60mL. YET, another criterion, effective orifice area, must be 0.3cm^2 for AR but 0.4 for MR.

#Medtwitter #cardiotwitter #POCUS #Echofirst
I kept mixing up which is 0.3 and which is 0.4. We can keep trying to memorize this, or ask why? Why is the regurgitant volume the same, but the effective regurgitant orifice area (EROA) different?

Here's the pearl:
It's because AR occurs in diastole, MR occurs in systole, and diastole is longer than systole. Therefore, in diastole, a smaller EROA (0.3) can generally yield the same 60mL of regurgitation as a larger EROA (0.4) can during the shorter systole.
Sure, there's still numbers to memorize, and digging further can help memorize even less. But for now, for those like myself mixing up which is 0.3 and which is 0.4, it should hopefully no longer be an issue.

#CCEeXAM @CardioNerds @msiuba @NephroP @nickmmark
Addendum:
AR is also defined by a vena contracta (VC) of 6mm, yet MR requires 7. This is likely for the same reason:
Diastole requires a smaller EROA *and* VC to achieve the same regurg. volume as a larger EROA & VC in the shorter systole.
More simply, larger EROA = larger VC.

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More from @JonahRubinMD

11 Mar 21
Excited for our upcoming Case of the Year Presentation by Drs. Hilary Zetlen and @tpeck_86, "Under Pressure: Trading One Problem for Another". Will be live-tweeting the case (to the best of my ability) below so you can follow along!
Read 53 tweets
23 Oct 20
Can blood transfusions increase an O2 sat from 80 to 87%?

YES! When the patient is on ECMO😆! (Or has a shunt…)

Buckle up for a hopefully understandable deep dive into some ECMO (/shunt) physiology with (⚠️warning) math and bad pictures.

🧵

#MedTwitter #MedStudentTwitter
First, to address the elephant and 44% who correctly say this is generally impossible: Normally, you *cannot* increase O2 sats by adding Hg, bc sats refer to the saturation of Hg. Adding Hg doesn’t enable the lungs to saturate the new Hg any more than all the Hg it had before.
But unlike "real"/"native" lungs (let’s assume they are completely non-functional here), which all the blood must pass thru, when a pt is on ECMO (an artificial or “membrane” lung), some blood goes through the ECMO circuit, but some blood doesn’t, and that’s where the fun begins.
Read 26 tweets

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