Monica Verduzco-Gutierrez, MD Profile picture
Jan 6, 2022 10 tweets 7 min read Read on X
Today I virtually lectured the residents from @BCM_PMandR & @UTHPMR about #LongCOVID.

I was touched that the residents wanted the slides & thought it was one of the most important talks of the year. Will share some in a thread 🧵 Selfie of Monica
We are still trying to figure out the pathophysiology of #LongCOVID... these are just a few of the hypothesis. But definitely inflammation and immune system dysregulation is involved.
2/ Image
We also know #COVID19 hyperinflammation and #PASC may be rooted in mast cell activation syndrome #MCAS 3/
ncbi.nlm.nih.gov/pmc/articles/P…
4/
So many #MCAS organ and system involvement overlap with #LongCovid Table from Afrin paper
5/ What does recovery really look like?
(And I promise you most #LongCOVID patients did not have #CovidLungs - they had mild disease) Image
6/ There is so much data that documents #LongCOVID now ImageImageImageImage
7/ Thankful for @patientled who is publishing amazing data
ncbi.nlm.nih.gov/pmc/articles/P… Image
8/ I have run a #LongCOVID clinic since August 2020 based on work I previously have done with TBI, stroke, dysautonomia, NeuroRehab, post-polio, critical illness recovery, and other post-viral illness like ME/CFS.
Getting close to 700+ persons seen.
9/ I continuously learn from the patients & I know it's not enough time, research, or treatments. #TreatLongCovid Image
10/ So much more to say on what we have been trying (but I need to go to clinic).

I was sure to emphasize topics often not taught in med school:
POTS
MCAS
ME/CFS

And to discuss health equity topics!

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More from @MVGutierrezMD

May 29, 2025
"How is this scientific?" That’s what I was asked while testifying in court on behalf of a person with #LongCOVID seeking work comp benefits. What followed was an attack on me, and on the legitimacy of infection-associated illness, lived experience, and equity in medicine. /🧵
The city attorney tried to discredit the #LongCOVID working definition
Yes, it’s symptom based. Yes, it’s broad & evolving. That’s how science works, especially when we’re studying a new condition. Definitions update as evidence grows. That is scientific.tinyurl.com/3akp459z
He questioned why the definition included things like #MECFS and fibromyalgia.
He called it “CFS” even after I corrected him.
He claimed these conditions “aren’t well diagnosed.”
Imagine dismissing real people and real suffering because there isn’t a single test.
Read 8 tweets
Sep 2, 2024
New paper out from my team at @FlowTherapyEECP using #EECP as a treatment for #LongCOVID symptoms.


In the last week, we've learned more about thromboinflammation & endothelial dysfunction in #LongCOVID, highlighting the complex nature of this condition.🧵 mdpi.com/2673-8112/4/9/…
Image
2/ Many COVID survivors continue to experience symptoms, significantly impacting their quality of life. There are limited treatments. Our recent study explored the use of Enhanced External Counterpulsation (#EECP), an FDA-approved, non-invasive therapy for cardiovascular issues.
3/ EECP works by stimulating pathways that improve microvascular function, inflammation, and immune regulation—potentially addressing the underlying causes of #LongCovid.
(Pic of me doing the treatment myself for my own long covid) Image
Read 7 tweets
Aug 8, 2024
1/ I've seen the "comment section," and many are saying that COVID-19 is just a mild cold and no big deal for athletes. But here's the truth: having any viral infection, including #COVID19, can significantly impact athletic performance and pose serious health risks. 🧵
2/ Even mild viral infections can reduce respiratory capacity, VO2 max, sleep quality, & elevate resting heart rate. This is especially concerning for athletes with conditions like asthma (which Lyles has). Though he did great, COVID cost Noah Lyles the gold. 🥇
3/ Running with these symptoms isn't just risky—it can be dangerous.
Engaging in athletic activity while sick with a virus dramatically increases the risk of a cardiac event.
Read 6 tweets
Jun 21, 2024
This recent study came out with little fanfare, but it’s something that overlaps with TBI & #LongCovid (two of my passions)
1/
Growth hormone treatment for neurologic symptoms of post‐acute sequelae of COVID‐19 ascpt.onlinelibrary.wiley.com/doi/10.1111/ct…
2/ BIAFAC is “brain injury-associated fatigue and altered cognition” that occurs in some patients with brain injury. It’s a combo of fatigue, brain fog, low GH secretion, hypoaminoacidemia, & gut dysbiosis.
In persons with BIAFAC, neuro symptoms are imprroved with GH treatment.
3/ I’ve worked with Dr. Randy Urban on both TBI & now Long COVID.
He had previously published that #longCOVID patients also have lower growth hormone secretion compared to patients that recovered from COVID without lingering symptoms. So they studied giving GH to persons with LC
Read 7 tweets
Jan 11, 2024
1/🧠Excited to get this to press in @AJPMR:
"EECP Improves Cognitive Function of Persons with #LongCOVID."
What did we find?
journals.lww.com/ajpmr/abstract…
2/ If you want to know more about EECP? Can see my prior thread here of my own experience with @FlowTherapyEECP...
3/ Impaired cognitive function/“brain fog” is reported in anywhere from 22-81% of PASC.
This was a retrospective analysis of Long COVID patients who had EECP. If they self-reported brain fog, an objective digital cognitive assessment (@BrainCheck) was done before & after EECP Image
Read 9 tweets
Jun 23, 2023
1/ At @theNASEM Symposium on Long COVID now listening to Jeanne Bertolli of CDC on perspectives from ME/CFS.
Limitations of definitions…
- Need involvement of those with lived experiences.
- Standardized evaluation of symptoms not required.
- Did not meet all needs
2/ committee came together in 2015 to create the IOM diagnostic criteria for ME/CFS:
https://t.co/Mog8rv3ysjnap.nationalacademies.org/catalog/19012/…
3/ For ME/CFS, documentation of infection or timing of onset not required. PEM is required.

Process used for defining this could help set a process for #LongCOVID
Read 17 tweets

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