THREAD on UK Covid situation:

TLDR: not over yet. Good news is high booster coverage in over 50s & no rise in ICU. Bad news is high strain on hospitals, no plan for schools & worsening admissions & long covid for kids.

+ Indie Sage has some suggestions...

1/21
Firstly Omicron - now dominant in Scotland, Wales & England. Probably in NI but no recent data. N Ireland is about week behind other nations.

Omicron dominant in all English regions, London c. 1 week ahead.

Omicron's rise has been very rapid! 2/21
Omicron is v good at infecting vaxxed people - even being boosted only gives you about 40% protection after 10 weeks.

Booster gives *88%* protection against hospital admission - GET IT!

NB booster hosp protection for Delta was close to 100%, Omicron has made things worse. 3/21
So given boosters so important... over 50% of whole population boosted everywhere except N Ireland.

Massive booster effort before Xmas but doses have dropped now :-(

England & NI behind on teen vax (about 50% have received 1 dose). 4/21
By age (England), we have excellent booster coverage in over 60s - this is making big difference to admissions and is why e.g. N America in harder situation. BUT plenty of unboosted younger adults left and kids have v little vax protection. 5/21
Plus very large gaps in booster coverage for adults and first dose for teens by deprivation.

We *have* to address this because it will only exacerbate existing inequalities if ignored. 6/21
In terms of cases... 3 million cases in last 3 weeks - same as in the whole 12 weeks before that.

Cases & positivity rates at record highs in all nations. Testing is struggling - ONS infection survey (not affected by test capacity) shows this peak dwarfs previous ones. 7/21
Reinfections are also rising - over 140,000 in England in last two weeks - these are *not* on the daily dashboard (but will be soon). Wales & NI do include these and so will be reporting relatively higher case numbers. 8/21
Regionally, London has dropped since pre Xmas but recent days flat. all other regions rising still.

Positivity rates rising everywhere (inc London!). ONS also shows recent fall in London but age profile is interesting... 9/21
Overall in England, confirmed cases in all ages are rising. ONS shows we're likely undercounting primary school kids - extremely high rates!

Kids are returning to school & young adults to uni with highest ever prevalence. 10/21
In London, drops in school age children and young adults since just before Xmas - but flat in most recent days - *before* any new year mixing impact.

Cases in older adults are still rising (although might be flatting in over 70s). What does this mean for hospitals? 11/21
Number of people in hospital with Covid is going up sharply - not *that* far from wave 1 peak.

BUT few people are needing intensive care - pressure there is NOT rising.

Both admissions *for* & *with* covid are rising steeply, *but* percentage for is falling. 12/21
There is a lot of staff sickness - climbing steeply.

This, combined with covid pressure + high existing hospital load + social care pressure, means many hospitals are in crisis.

NHS doesn't have same resilience 2 yrs into pandemic. NW particularly stressed. 13/21
Deaths are hard to interpret right now with reporting delays over holiday period, but are likely flat or slightly increasing.

With fewer people needing intensive care and high boosters in older adults, hope that deaths will not increase too much... 14/21
If we look at the age of admissions, they might be peaking in 18-64 year olds but still going up in over 65s.

Admissions are at record highs for under 18s, *particularly* for *0-5s*.

More children have been admitted with Covid in *last 3 weeks* than *whole of 1st wave*. 15/21
If we look at long covid, children reporting symptoms longer than 4 weeks has shot up, sharply reflecting high case numbers in Sept & Oct. Adults in their parents' generation (35-49 yrs) also reporting increasing long covid. 16/21
Long covid reports in 17-24 yr old has fallen, reflecting more people recovering than being added as cases have fallen - good. But we've just seen record cases in this age group - and we have no idea about Omicron and Long Covid. Vax should help, but no omicron data. 17/21
As for kids - we know they've got more months of high (Delta) cases that will increase long covid. AND they've returned to school & likely Omicron wave. What then?

With increasing long covid & hosp admissions & little vax, we must stop pretending covid fine for kids. 18/21
Also, a new school wave will prolong the Omicron wave for everyone, and further risk school staff (already reporting more long covid alongside health care workers).

AND high school cases disrupt education for kids who fall ill and those left without teachers. 19/21
So @IndependentSage think it's too late for a circuit breaker - time for that was in Dec. Now it's about reducing the "comedown wave" as fast as possible through:
communication (symptoms, airborne)
protection (clean air, masks, vax)
support (isolation, clean air, industry) 20/21
Different ages will peak at different times. The risk of "muddling through" is that we face a slow descent, resulting in far too much illness, disruption and prolonged NHS pressure.

We didn't slow growth of Omicron, so let's now accelerate its decline. 21/21
PS incidentally, all the measures we've suggested are important for new variants, and most for new airborne diseases...

PS2 thanks to Bob Hawkins for his help as ever.
PS3 you see same patterns of long covid (but lower numbers) when looking at symptoms for longer than 12 weeks - but that still only includes people infected up to September because of lags and so misses school wave.

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More from @chrischirp

9 Jan
A virus isn't endemic just cos a govt minister says it is and just cos people want it to be.

The current pattern of waning vax, new immune evasive variants, and minimal public health response seem set to doom us to massive surges once or twice a year. 1\5
If that continues we'll keep picking off the vulnerable, keep stressing a weakening NHS, create more chronic illness & mass disruption through people off sick every time. Lower quality of life for all of us.

Uncertainty in being able to plan months ahead cos of variants 2\5
And when the next pandemic comes, do we just add that disease to our repertoire after a period of mass death?

What when diseases like malaria move north through climate change?

What about rest of the world?

We're moving backwards. 3\5
Read 5 tweets
2 Jan
I rarely quote tweet but this is not right.

Firstly, it's airborne - that means aerosols are as important as droplets.

That means masks and ventilation are crucial steps and both necessary.

Second, there is excellent evidence on masks in schools: 1/4
Read 6 tweets
30 Dec 21
THREAD on England & Omicron and what is going on.

My take on it.

TLDR: things are pretty bad and I'm sad & bewildered at lack of govt action and general levels of hopium. 1/18
First off cases... reported levels in England now more than twice as high as previous peak last January and more than three times higher than at start of December.

Latest numbers reflect infections *before* Christmas mixing.

These numbers are an underestimate.

2/18
Positivity rates are also rising v steeply - testing is not keeping up with cases.

All regions rising fast, London highest and earliest. Do not take London small case drop too seriously - drop in pre xmas tests & positivity still rising. Plus xmas likely to boost again. 3/18
Read 19 tweets
29 Dec 21
I wrote this with @adsquires because next term is coming quickly and we need to plan for how to *minimise* infection in kids & teachers and *minimise* disruption to education.

Govt still not doing anything - so this thread summarises what I am afraid will happen:

1/9
We've recorded over *1.2 million* infections in 5-14 yr olds in England since 1 Sept 2021. The real number will be much higher.

Over 2,500 6-17 year olds have been admitted to hospital with Covid since then too and ten 5-14 yr olds have died due to Covid. 2/9
Thousands more children are reporting long covid through ONS infection survey.

V big disruption to education, with 1000s of children missing school every day & teachers off sick.

Hardly any under 12s & *fewer than half* of 12-15 yr olds have received a single vaccine dose. 3/9
Read 10 tweets
24 Dec 21
Was going to do a quick pre-xmas thread on where we are but SAGE minutes from their meeting yesterday covers all my points!

So here is a whistestop tour of the main bits

Omicron Growth might be slowing, but only from ~2 day doubling to ~3 day doubling. So still growing fast.
Not clear why growth is slowing: likely combo of more cautious behaviours, Plan B (e.g. work from home), moving to different age groups, more reluctance to test
Number of people in hospital with Omicron doubling every 4 to 5 days – this is rapid and so far they are younger. Also increases in transmission within hospitals. SAGE expects large increase in admissions as older people get infected over Christmas ☹
Read 9 tweets
21 Dec 21
THREAD on cases, hospital admissions and why so many scientists & NHS leaders are worried.

Case study of London - and what is behind the alarm!

1/10
The key bit is that it takes about 10-14 days from infection to needing hospital. And if you have symptoms, you'll probably test positive 4-7 days into infection.

So there's roughly a week from testing positive to becoming a hospital admission. 2/10
So - cases in London have risen *very steeply* - but *mainly* in the last week. And only in the most recent week has Omicron been dominant.

But cases to 19 Dec (incomplete!) are already more than double previous week. 3/10
Read 10 tweets

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