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Dr Nisreen Alwan 🌻 Profile picture
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9 Jan, 4 tweets, 2 min read
I missed this study from few months ago. Interestingly though sample relatively small and only basic analysis, the preliminary finding of lower antibody levels in those with more severe fatigue gives support to the link between immune response & #LongCovid
mdpi.com/2077-0383/10/1…
Remember this study I tweeted about months ago?
Also points to a link between Long Covid and weak antibody response to covid:
link.springer.com/article/10.100…
Two main implications for this:

1. It is useless to use antibody levels to assign cases and controls when studying prevalence of Long Covid. More here:
nisreenalwan.wordpress.com/2021/10/16/lon…
2. It supports the generally positive direction we found so far in relation to the link between vaccines and Long Covid symptoms:
medrxiv.org/content/10.110…

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More from @Dr2NisreenAlwan

Dr Nisreen Alwan 🌻 Profile picture
9 Jan
The UK’s Medicines and Healthcare products Regulatory agency declared the Pfizer covid vaccine safe & effective for 5-11 year olds with a positive benefit risk. However the vaccine is yet to be *offered* to all UK kids in this age group. Parents currently don’t have that choice.
Offered in Spain since 15 December according go this:

euractiv.com/section/all/sh…
Also in Germany:

thelocal.de/20211213/germa…
Read 11 tweets
Dr Nisreen Alwan 🌻 Profile picture
7 Jan
So Omicron and #LongCovid, what’s the deal?

Short 🧵
1/9
 We don't know yet how much long term disability Omicron will generate, but it’s not only a matter of time. Separating the effect of vaccines (including boosters) from the effect of the variant will be challenging.
2/9
 Breakthrough infection (in the double vaccinated) seems to be associated with less risk of LC. Obviously the evidence comes before Omicron. Also, there’s no evidence I’m aware of on the risk of LC in post booster infection (after 3 doses) whatever the variant.
3/9
 Good news about vaccines if we assume the same applies to Omicron, but I’m still concerned. That’s because we have so much more infection with this wave, so even if the risk of LC with Omicron and vaccines is half or a quarter of what we had before, that’s still a lot of LC.
Read 9 tweets
Dr Nisreen Alwan 🌻 Profile picture
7 Jan
I have several criticisms of this @BBCNews piece but I honestly can't believe that it includes this statement expressed as a fact, particularly that most UK adults are vaccinated and most kids are not:
"Children are less likely than adults to catch Covid"!
bbc.co.uk/news/health-57…
Other stuff:
1. There is actually a WHO definition:
who.int/publications-d…
2. ONS LC numbers following up confirmed infections published in Sep 21: Approach 3 is the most accurate IMO because it's not limited to assessment of listed symptoms so takes relpasing nature into account. That's 11.7% out of all infected, 17.7% out of those acutely symptomatic.
Read 6 tweets
Dr Nisreen Alwan 🌻 Profile picture
6 Jan
OMG I can’t believe my eyes! Finally an MP calling for protections against covid in primary schools.
Thank you @MpHendrick
You maybe interested to read this.
Also here are some concerning stats about #LongCovidKids:
Read 4 tweets
Dr Nisreen Alwan 🌻 Profile picture
5 Jan
If the UK authorities decide to follow the US in reducing covid positive isolation period to 5 days, here are some things that might lessen any negative impacts (in my opinion):

🧵
1/7
Be upfront about why you’re doing it: pragmatism and capacity. Acknowledge that at this stage there is no scientific basis that completely rules out being infectious after 5 days with Omicron or other variants. Honesty is a great public health approach.
2/7
Require a rapid antigen test to be negative on day 5 before ending isolation.
3/7
Read 8 tweets
Dr Nisreen Alwan 🌻 Profile picture
3 Jan
Primary schools in England are opening tomorrow with no mask recommendation, no adequate ventilation measures and no vaccine offer for all 5-11 year olds in the context of 1.1 million confirmed covid cases during the last 7 days in the UK.
#CountLongCovid
inews.co.uk/news/7000-air-…
Read 5 tweets

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