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More from @yaneerbaryam

12 Jan
No Surrender - Where There's a Will There's a Way


@smbilodeau @CecPhil @M_F_Schneider Sunil K Raina @DrEricDing @nntaleb @ShutiChiou

JAMA released Comment on:
A National Strategy for ... COVID…

Emanuel, Osterholm, Gounder (EOG) propose that, in contrast to a zero COVID policy, we surrender to the pandemic, setting an acceptable level of deaths as policy success.

In an accompanying article Michales, Emanuel, and Bright propose this can be achieved by improved vaccination, testing, surveillance, masking, ventilation and distancing.

Read 17 tweets
12 Jan
New paper: Mice and Men have Covid brain damage

Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

Cancer therapy cognitive impairment and Covid have similar patterns of brain damage

Survivors of SARS-CoV-2 frequently experience lingering neurological symptoms: impairment in attention, concentration, speed of information processing and memory.

This long-COVID cognitive syndrome shares many features with the syndrome of cancer therapy-related cognitive impairment (CRCI).

Neuroinflammation, and dysregulation of hippocampal neurogenesis is central to CRCI.

Read 5 tweets
6 Jan
New Zealand is almost back at elimination!

Community transmission (top figure) declining
Dec 31: 49
Jan 1+2: 105
Jan 3: 27
Jan 4: 31
Jan 5: 17
Jan 6: 19

Traveler quarantine cases increasing, mostly Omicron going into quarantine facilities, up to 43!

Congratulations! Image
Very high vaccination, very high masking (including a lot of N95s), local restrictions based upon local conditions.
Read 4 tweets
5 Jan
More than 1,000 faculty members at Univ of Michigan have vowed to teach online today, or to help those who do, defying an order from president Mark Schlissel. Faculty members say they don’t want to teach in person because of risks of getting COVID-19.…
Here is a relevant thread.

Faculty members are among the professions whose future might be affected by Covid brain damage. Not sure how the university thinks it will fare with significant harm to tenured faculty.

To be clear, I think everyone should be concerned about long Covid. I am just amazed that it isn't on the agenda more widely.
Read 4 tweets
2 Jan
Addition: the genetic combinations of Omicron and Delta that form when someone is infected by both can be expected to result in new variants with a wide range of properties.
Don’t think about the virus as what it is today but what it might become.

The virus has a very large space of possible options. Omicron has 60 mutations, another combination of 60 mutations will result in very different properties.
If we don’t want more possibilities there is one sure way that will prevent it: reducing the amount of virus that is transmitting. We are doing the opposite so far, there is more virus not less.
Read 4 tweets

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