in the fruit machine fallacy the 'digits' of a genome are treated as though they are wheels of a fruit machine.
roughly: you look at a sequence of nucleotides, at the number of possible types for each nucleotide, and calculate the odds of recreating the sequence of interest if all nucleotide types were set at random.
you're calculating the odds of getting this particular sequence if you pulled the lever once on an imaginary nucleotide fruit machine.
there are important differences with real life that the fruit machine math doesn't account for. and which invalidate this approach.
1. evolution works with what already exists and small incremental mutations. so if a virus existed that was already very close to SARS-CoV-2, the odds of SARS-CoV-2 emerging in any given period would be much higher. the fruit machine math doesn't account for this consideration.
2. related to 1, while a virus is active there are a great many pulls of the lever (which may or may not 'spin wheels' and create mutations). not just one.
i deleted my most shared tweet. rip. i believe the part about '1 in a billion' is too ambiguous and/or not supported. i don't know how we'd approach putting a likelihood on the #CTCCTCGGCGGGCACGTAG sequence in moderna's patents coincidentally also ending up in SARS-CoV-2
the rest of the original thread here: rest of the original thread here:
the 1 in a billion claim can make sense if simplifying each 'slot' in a genome to something like the wheel of a fruit machine, pulling the lever, and checking the output for occurrences of the query string.
many otherwise smart seeming people claiming that the risk of harm from vaccination is very small.
no. we don't know what the risks are. because: 🧵
1. there's no rigorously collection of adverse events. only passive systems like VAERS. VAERS, known to be subject to massive underreporting, *is* seeing many times more reports than the increased rate of vaccination alone would predict. this is ignored by 'authorities' so far.
2. there is no routine testing for subclinical damage post vaccination. nor was there any biomarker testing for the possibility of such damage in the trials - for instance micro clots.
as far as I can tell, the risk, by the way has entirely to do with the user needing to precisely measure out a correct weight-adjusted dose themselves.
this, needless to say, is not medical advice. and neither is what the FDA is flippantly shitting out above.