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Jan 20 • 5 tweets • 4 min read
1/5 BREAKING: #SputnikV shows strong protection against #Omicron, over 2x higher virus neutralizing activity vs Pfizer vaccine, in independent study by EU-based Spallanzani Institute @INMISpallanzani.

READ👇
sputnikvaccine.com/newsroom/press…
2/5 Study, conducted in equal lab conditions in Spallanzani Inst in Italy on comparable sera samples, shows Sputnik V induces 2.1x higher virus neutralizing antibodies titers than 2 doses of #Pfizer jab in total, 2.6x higher 3 months after vaccination
👇
medrxiv.org/content/10.110…
3/5 Reasons for Sputnik superb Omicron performance:

• Wide pool of antibodies vs Pfizer’s less flexible proline-stabilized structure producing antibodies to most mutated virus part

• Mix&match scheme with 2 different shots

• Adenoviral vectors better mimic natural infection
4/5 Spallanzani study: Among top quartile of people with high RBD-specific IgG antibodies 100% vaccinated with Sputnik V were able to neutralize Omicron variant in comparison to 83.3% of individuals vaccinated with #Pfizer
5/5 Based on data by Spallanzani Inst & results of other studies, mix&match boosting with Sputnik Light is the best solution to increase other vaccines efficacy&extend period of protection against #Omicron

WATCH ON TWITTER AT 1400 CET | Video announcement

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More from @sputnikvaccine

Sputnik V Profile picture
Jan 20
1/5 ÚLTIMO MOMENTO: #SputnikV muestra una fuerte protección contra #Ómicron, más del doble de actividad neutralizante frente a Pfizer, en un estudio independiente realizado por el Instituto Spallanzani con sede en la UE @INMISpallanzani
LEER 👇
sputnikvaccine.com/esp/newsroom/p… Image
2/5 El estudio realizado en Inst. Spallanzani, en Italia, en muestras de suero comparables, muestra que Sputnik V induce anticuerpos neutralizantes 2,1 veces más altos que 2 dosis de Pfizer en total, 2,6 veces más alto 3 meses después de la vacunación
👇
medrxiv.org/content/10.110…
3/5 Gran rendimiento de Sputnik por:
• Amplio conjunto de anticuerpos frente a estructura estabilizada con prolina menos flexible de Pfizer que produce anticuerpos contra partes mutadas del virus
• 2 dosis distintas
• Vectores adenovirales imitan mejor la infección natural
Read 5 tweets
Sputnik V Profile picture
Jan 20
WATCH | Key slides from presentation on Spallanzani Institute independent study on Sputnik’s protection against #Omicron.

#SputnikV shows strong protection against #Omicron, over 2x higher virus neutralizing activity vs #Pfizer vaccine.
1/9
2/9
Read 10 tweets
Sputnik V Profile picture
Jan 3
In recognition of quickly waning Pfizer vaccine efficacy US FDA recommends reducing interval for Pfizer booster shot from 6 months to 5 months. Instead, booster by other vaccines is needed to lengthen Pfizer vaccine protection particularly against #Omicron
Read 5 tweets
Sputnik V Profile picture
Dec 30, 2021
Gamaleya Institute: “Russian Ministry of Health recommends Sputnik Light booster 6 months after vaccination to increase protection against #Omicron and other mutations.” Sputnik vaccines showed high level of virus neutralizing antibodies and T cells against #Omicron Image
Sputnik Light is a universal booster to other vaccines for fastest, strongest and longest protection against #Omicron and other mutations.
👇
indiamedtoday.com/sputnik-v-indu…
Read 6 tweets
Sputnik V Profile picture
Dec 28, 2021
1/4 Sputnik team has been the 1st to raise issue with quickly dropping efficacy of mRNA vaccines and relentlessly offered cooperation through mix&match/combo vaccine approach that works better against emerging mutations such as #Omicron and #Delta.

2/4 On September 17, 2021 we suggested that Sputnik Light booster will help Pfizer vaccine last longer.
3/4 We even offered to help “dress the Emperor up”

Read 4 tweets
Sputnik V Profile picture
Dec 28, 2021
5 studies on quickly waning mRNA vaccines that make countries cut mRNA boosters time to 3 months/introduce 4th mRNA booster

Boosting by other jabs will prolong mRNA immune response

@JAMA_current: mRNA efficacy vs #Delta among elderly 20% after 4 months👇jamanetwork.com/journals/jaman…
2/5 According to Swedish data Pfizer vaccine’s efficacy against #Delta COVID strain is falling to below 30% after 6 months.
👇
papers.ssrn.com/sol3/papers.cf…
3/5 The UK Health Security Agency said those who had received three doses of Pfizer’s vaccine saw their protection against symptomatic illness caused by #Omicron variant drop to 45 percent within 10 weeks.
👇
gov.uk/government/pub…
Read 5 tweets

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