- LAA is more compliant than LA
- LAA acts like a decompression chamber during systole
- The capacitance/reservoir role is key when LAP is elevated
- Eliminating LAA acutely ⬆️ LA pressure in dogs
- Effect of LAAO on hemodynamics in humans is debatable
- OBS data ➡️ that LAAO ⬆️ LAP, ⬇️ LA transport function, ⬆️ HF
- However, in LAAOS III RCT there was no ⬆️ in HF admissions w LAAO
- Caveat: epicardial closure vs ednocadail plugging of LAA don’t produce similar effects
Pros: 1. No resources/funding required 2. Gain in-depth knowledge in a specific area 3. SOA reviews are highly cited 4. Excellent venue to hone✍️skills
Cons: 1. Time consuming 2. Not a substitute 4 original🔬 3. Unpredictable fate
How do I select a topic?
1. ✍️ on broad topics if no good 📝 exist (eg, SCAD, aneurysms, TV interventions), or if u find a novel angle (eg, stakeholder perspectives on stroke prevention in AF)
2. ✍️ on niche areas (eg, electrosurgery, ICE for LAAO, TAVR leaflet thrombosis)