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Luca Arcari Profile picture
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Feb 11 • 8 tweets • 3 min read
1/ Case of te day, classic #HCM @beamusumeci1 @TiniGiacomo @domitillarusso
2/ Bright area in the LV septum/anteriore wall, seen already from trufi scout ... #WhyCMR
3/ That is edema (T2 STIR)
4/ Classic LGE at insertion points, not so large, not a bad prognostic sign. Edema partly matches scarred area
5/ Native T1 assessed outside scarred area, increased (diffuse fibrosis/edema)
6/ normal T2 in the area of increase T1 (fibrosis more than edema) - increased T2 (>50 msec) within the bright Stir region. Kill the colours by windowing, parametric assesment of T2 maps is more reliable than visual evaluation
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The missing T2 map

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More from @Luca_Arcari88

Luca Arcari Profile picture
Feb 9
No, non è un bene scaricare le responsabilità sulla magistratura (thread) 🧵
@corzunino @PrecariUnitINFN @IoNonFaccioNien @MC_Carro
1/ Premessa - “Nell’università italiana il reclutamento segue nei fatti logiche slegate dai regolamenti concorsuali ”
Senza polemiche e moralismi, se si nega questo stato dell’arte, si può interrompere qua la lettura
2/ Il reclutamento nell’accademia è fatto di cooptazione, in Italia come nel resto del mondo. Necessariamente, per selezionare, il giudizio deve essere espresso da chi è esperto della materia, il cortocircuito è inevitabile e i grandi grant internazionali non ne sono esenti
Read 11 tweets
Luca Arcari Profile picture
Jun 12, 2021
Finally published on @journalofCMR!!! Cardiac biomarkers and #WhyCMR T1 and T2 mapping in people with chronic kidney disease - Thanks to @GoetheCVI @v_puntmann @c_eike jcmr-online.biomedcentral.com/articles/10.11… Few considerations below.
We found independent associations between increasing natriuretic peptide/hsTropT on one side and myocardial involvement as assessed by native T1 and T2 mapping on the other ➡️ cardiac biomarkers=cardiac involvement (not only reduced elimination). (1/3)
Is cardiac involvement characterized by diffuse fibrosis only? Likely not: increased T2=contribution of myocardial edema. ❗️❗️T2 decreases after hemodialysis, proportionally to revomed volume❗️❗️ (2/3)
Read 6 tweets
Luca Arcari Profile picture
Sep 28, 2020
Just published our latest work.

Investigating myocardial involvement in #COVID19 by troponin and BNP: dual center study on the first wave in Lazio region, Italy. link.springer.com/article/10.100… @mikeolangel @beamusumeci1 @P_Martelletti. Here it follows some considerations.
1. Increase of troponin/BNP was common in our sample, higher in patients with worse in-hospital prognosis (consistently shown in literature). Take into account epidemiological characteristics of the population: older age, high rate of comorbidity and fatal outcome.
2. Troponin and BNP generally had parallel increase, both in relation to A) markers of disease severity (D-dimer, CRP, P/F) and B) pre-existing condition of vulnerability (age, previous CVD, renal insufficiency etc.). However,
Read 7 tweets
Luca Arcari Profile picture
Aug 15, 2020
Just published on @SciReports: disq.us/t/3qzu3fo,
Role of dyspnea at presentation in #Takotsubo. Thanks to
@FraSantoroMD @beamusumeci1 @lucarlimite @IngoEitel. Here it follows some considerations.
1- Dyspnea was associated with both worse in-hospital and long-term outcome. Similarly described in AMI (ref #12 and #13) in which heart failure symptoms at presentation might reflect wider myocardial damage. Why is it so even for a “transient” condition such as #Takotsubo?
2- Dyspnea was independently associated with both higher cardiac impairment and comorbidity burden, intuitively linked to the worse prognosis in the acute phase. And long-term, after recovery of cardiac function? We tried to give two possible explanations (just hypothesis).
Read 9 tweets

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