Whenever I post something about longCovid it’s usually the most RT. My sense is that the human suffering from the Covid pandemic due to longCovid especially in the US is enormous and we’ve only begun to unravel this. Asking @AliHMokdad @IHME_UW on some longCovid DALY estimates
DALYs = disability-adjusted life years, roughly years lost due to premature deaths or disabilities. I use @IHME_UW DALY estimates to help policymakers understand the debilitating effects of parasitic infections/NTDs, but this also could be a powerful advocacy tool for longCovid
Also the underlying molecular and immunological mechanisms for longCovid are fascinating but chilling. Some really interesting things, autoantibodies, microglial activation, some of this work by @VirusesImmunity
If I were starting over in science I would give serious thought to working on this infection-neuroscience axis through systems biology and other approaches. It would teach us not only about longCovid but things like CFS, fibromyalgia, other post-infectious sequelae
It’s also another reason I bristle at antivaccine activists who show no compassion for longCovid sufferers or who focus on ways to deflate the death stats among young and middle age adults or kids

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More from @PeterHotez

Feb 12
Among reasons I advocate for Americans to vaccinate: to prevent longCovid. Recent ⁦@CDCMMWR⁩ shows vaccination/boosting 3.6x reduction in infection. Vaccine refusal causes 23x increase in hospitalization but also longCovid consequences r devastating nytimes.com/2022/02/12/wel…
I think this article from @UniofOxford @medrxivpreprint is among the more important longCovid articles and a reason I push hard to max out vaccinations and boosters to halt infection medrxiv.org/content/10.110…
Read 5 tweets
Feb 12
Many thanks ⁦@ErinBurnett⁩ for hosting me ⁦@OutFrontCNN⁩ on two important pieces of information related to 1) pediatric vaccinations for under 5 and 2) waning effectiveness for boosters
Regarding under 5 vaccinations we’ve known at the 3 microgram dose would require 3 doses in the 2-4 yo age group. The question is was there enough effectiveness with 2 doses to move forward now with expectation it would improve following the 3rd, especially bc of omicron storm
But @washingtonpost reported today that new data coming in last night gave the regulators pause on the effectiveness of 2 doses + omicron wave decelerating as fast as it went up, hence perhaps less urgency and therefore just wait for 3rd dose data in April
Read 6 tweets
Feb 9
1/4 Many thanks ⁦@ChrisJansing⁩ for hosting me on ⁦@RuhleOnMSNBC⁩ my rationale for holding off another 2 weeks on lifting mask restrictions is as follows. We’ll know by then where we’re heading with Covid. Two different scenarios and we might know by then…
2/4 Scenario 1: covid continues its steep declines or deceleration and we reach a nadir, that’s a best case scenario and masks restrictions can probably lift
3/4 Scenario 2: Following BA.2 sub variant which is 30-50% more transmissible than original omicron variant if you can believe that. Now 3.6% of the US virus isolates are BA.2, it’s crunch time and we’ll know in 2 weeks if we have another tiger by the tail
Read 5 tweets
Feb 8
We have just reached 80,000 COVID-19 deaths in the state of Texas: My graphic interpretation of the COVID-19 deaths before vaccines were widely available ("the virus") vs deaths after May 1 resulting from vaccine refusal and defiance ("anti-science")
The trajectory of the deaths is from NY Times COVID-19 tracker for State of Texas, also here's a background article from @TexasTribune based on data from @TexasDSHS texastribune.org/2021/11/08/tex…
Detailed discussion and my comments @HoustonChron ICUs still full as Houston COVID-19 cases continue to plummet houstonchronicle.com/news/houston-t…
Read 5 tweets
Feb 7
Here’s why this is important. The nation still has tough Covid challenges ahead, and we urgently need strong leadership across multiple HHS agencies. Will summarize some of them in the attached tweets… cnn.com/2022/02/06/pol…
1: BA.2 some evidence that it’s even more transmissible than the original omicron which is more transmissible than delta, and so forth. If it takes hold like it did in Denmark it will slow the descent of original omicron here
2: Once we get through this omicron wave we’re likely still vulnerable to future waves of as yet unknown variants of concern. We need a planning strategy of how to manage a potential new variant in Texas and US Southern states this summer, or annual winter waves of Covid
Read 8 tweets
Feb 5
Many thanks ⁦@AlexWitt⁩ for hosting me from the mountains beautiful Utah today where I’m speaking at a medical conference. I offered on my opinion on where we might head next in the coming months…
The hope is that omicron continues to decline in the US as fast as it accelerated. So far that seems to be what’s happening but we need to be careful: after omicron began its descent it got stuck halfway down and still remains
And you have the situation in Denmark 🇩🇰 where the BA.2 sub variant is creating problems, so omicron and it’s subvariants could be with us for a while..
Read 6 tweets

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