This one found an association between the implementation of restrictions on high fat, salt, and sugar advertising and relative reductions in energy, sugar, and fat purchased from such products.
- In November 2018, restrictions on the outdoor advertising of HFSS foods and drinks across the Transport for London (TfL) network were announced by the Mayor of London, UK.
- The TfL advertising estate includes the London Underground (rapid transit) network, the TfL Rail network, transport vehicles run by TfL (including some buses, trains, and taxis), and outdoor spaces owned by TfL (e.g., bus stops and land outside train stations).
- The restrictions were fully implemented on 25 February 2019.
- The introduction of advertising restrictions for HFSS products across the London transport network was associated with a relative decrease in average weekly household purchases of energy from HFSS products of 6.7%, or 1,001.0 kcal.
- Using the mean household size of 2.6 people in the sample, and assuming an even energy distribution, this equates to a relative reduction in purchased energy of 385.0 kcal per person per week, which is equivalent to approximately 72.1 g of standard milk chocolate.
- Relative reductions in weekly household purchases of fat (57.9 g), saturated fat (26.4 g), and sugar (80.7 g) from HFSS products were also observed.
- The largest relative reduction for chocolate and confectionery (19.4%; 317.9 kcal).
- However, decreases associated with the intervention are in the context of underlying increases in purchases of HFSS products in both the intervention and control areas over the study period.
This means that the intervention was associated with a reduced rate in growth of HFSS purchases in the intervention group rather than an absolute reduction in HFSS purchases.
Changes in household food and drink purchases following restrictions on the advertisement of high fat, salt, and sugar products across the Transport for London network: A controlled interrupted time series analysis (open access)
This systematic review and meta-analysis of RCTs comes to the conclusion that ~700 METs-min/week is the minimal dose to elicit clinically important changes in cognition in older adults.
- The estimated minimal exercise dose found that can elicit clinically relevant changes in cognition was 724 METs-min per week, with doses beyond the upper bound of WHO recommended level of physical activity providing less clear benefits.
- 724 METs-min per week is slightly above the lower bound of WHO recommended level of physical activity (i.e. 600 METs-min per week, equivalent to 150 min/week of moderate intensity or 75 min/week of vigorous activity).
This one suggests that conventional daily caffeine intake does not provide sufficient time for the elimination of caffeine and paraxanthine.
- Worse still, even though the salivary caffeine nearly reaches a clear state, the caffeine-associated brain responses seem to require a longer time to be fully restored.
"The concurrence of a reduced hippocampal GM intensity and an incomplete caffeine elimination, together with a GM recovery after being deprived of caffeine, underscore the importance of a sufficient cessation period...
This Mendelian randomization analysis suggests that VAT mass is associated with a wide range of CVD outcomes including coronary heart disease, cardiac arrhythmia, vascular diseases, and stroke, with some circulating proteins being potential mediators of this association.
- Among these proteins, genetically estimated VAT mass had the highest OR value for the expression of leptin.
- Excessive VAT increased the level of leptin and further increased the incidence of all-cause heart failure, atrial fibrillation and flutter, DVT of lower extremities, pulmonary embolism, and DVT of lower extremities and pulmonary embolism.
This systematic review and meta-analysis aimed to investigate the efficacy of increasing dietary protein ingestion to improve lean body mass gain, skeletal muscle strength, and physical function in healthy subjects.
- Additional protein ingestion together with resistance training leads to small additional lean body mass and lower body strength.
- This effect seems to be more prominent in younger subjects ingesting ≥1.6 g/kg/day.
This study explored the effect of three different modes of resistance training on appetite hormones, cardiometabolic and anthropometric measures in males with obesity.
- 44 males with obesity were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups.
- All resistance training groups received 50 min of supervised training per session, three days per week, for 12 weeks.
This one suggests that individuals with high serum microRNA-122 levels may be less responsive during diet/physical activity-induced weight loss, as far as hepatic fat content loss is concerned.
- In the current study of participants with abdominal obesity or dyslipidemia from an 18-month randomized, controlled diet and physical activity intervention trial, it was observed that serum miR-122 levels were positively associated with hepatic fat percentage at baseline.
- A greater elevation in miR-122 from baseline to 18 months was associated with a smaller reduction in hepatic fat content during the 18-month intervention process.