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Eric Feigl-Ding Profile picture
@DrEricDing
Mar 8, 2022 • 17 tweets • 11 min read • Read on X
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⚠️UPDATE—#BA2 is now 11.6% in US, up from 8.3% last week. It’s definitely increasing, as warned. #COVID19 still dropping, but BA2 is growing in underbelly—it’s a matter of when (not ‘if’) case drop plateaus, then reverses. Likely late April, early May.🧵
covid.cdc.gov/covid-data-tra… ImageImage
2) Where is #BA2 highest? In New England (HHS region 1), where BA2 is already 24% of all cases. It’s definitely outcompeting the old original #Omicron which is fading away. Image
3) #BA2 is not mild among unvaccinated and under-vaccinated populations. In Hong Kong 🇭🇰 where BA2 is very dominant, hospitals and morgues are overflowing. Hong Kong has never had a surge of this kind before - not until BA2 showed up.
4) But some say HK hasn’t been hit hard by old Omicron, unlike US or UK. So what’s happening in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 then with its BA2 rise? Let’s check in— hospitalizations are rising in all age groups. Especially in kids 6-17, surging 26% in hospital admissions in one week. 👇
5) Some are asking how bad is #BA2 in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 anyway— their last variant update was FEB 25th, but it shows roughly ~1/4th BA2– it’s not even that high of a percentage. Maybe it’s closer to half now but not dominant—yet hospitalizations up already.
assets.publishing.service.gov.uk/government/upl… Image
6) How fast is the relative rise of #BA2 versus the emergence of other variants? Early on, it matched the old #Omicron for a while… slower now but still faster than older variants. This is not a good sign. Image
7) HOW IT STARTED… HOW ITS GOING… by region in the US, compare one month ago on Feb 5th… versus now March 5th data see anything wrong with the pink pie charts? #BA2 is growing. I’ve seen this rodeo 4 times before. New variants displace old ones for a reason—it’s not good sign. ImageImage
8) Back to Hong Kong— just how bad is #COVID19 deaths in 🇭🇰 right now? It is almost “Holy Mary” bad. It’s higher than any record high that US or Europe has ever seen. When hospitals 🏥 & morgues overloaded, it’s not merely “with COVID”—it’s directly COVID. HK is undervaccinated. Image
9) If we just look at the recent (old) Omicron wave, HK’s surge makes the recent really bad Omicron wave look tepid (it’s not —it’s the second worst wave the US had). The new HK BA2 is that severe. Maybe the Us might fare better initially—but I worry about waning immunity by May. ImageImage
10) Meanwhile, The good news is that #Omicron responds to Boosters well — 90-95% protection against hospitalization. However, 2 shots “basic” vax isn’t enough anymore versus Omicron—protection now only 70-79% depending on agent group. ➡️Note—70% is 3x worse than 90% if inverted.
11) the secondary ATTACK RATES (infection in secondary household members and in workplaces) is also much higher with #Ba2 than other variants. 14.3% is quite high and about ~25% ⬆️ higher than BA1’s 11.4%. Basically it’ll cross infect more people. This is why it’s a bad sign. Image
12) Furthermore, in non-household settings, the secondary ATTACK RATE (cross infection to others) is 6.1% for #BA2. but that is 32.6% ⬆️ higher than BA1 (old Omicron). This again is not good. Image
13) REMINDER that #covidisairborne. Please try to mask - but if you don’t, please buy a HEPA filter or build a Corsi-Rosenthal Box 📦 filter. See thread 🧵 below 👇
14) #Ba2 is now ~1/4th of all cases in Ontario—even with incomplete sequencing data. This is a spike of 40% increase from last week alone.
15) Again, don’t be misled by falling cases. While total cases may be dropping (of the older variants), there can be an “under growth” in the underbelly, that when it becomes dominant, will crisscross and then cause a new surge. We have seen this before countless times.
16) Too many people are selfish and lacking in compassion during the pandemic. This is one of the fundamental reasons that #CovidIsNotOver. I explore many of the fallacies below 👇
17) The trends for #BA2 in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 are quite alarming. 👇

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More from @DrEricDing

Eric Feigl-Ding Profile picture
Feb 21
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏 Image
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2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”

pmc.ncbi.nlm.nih.gov/articles/PMC10…
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 16
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)Image
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2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)."
nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.

"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"Image
Read 13 tweets
Eric Feigl-Ding Profile picture
Feb 14
⚠️WORST FLU SEASON ever since 2002-2003 when we began to track flu (red, first graph). Worst hit this year are children ages 0-4 and 5-17. ▶️We also have significantly LOWER flu vaccine uptake this year, one of the lowest flu vaccine coverages (red 3rd graph). Indisputable facts. Image
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2) I don't need to tell you that certain US states have vastly lower vaccination rates than others. See map (lighter green, less flu vaccination coverage), and which have higher (darker green)...

If you want to see details and demographics on which state has the LOWEST flu vaccine coverage rates... the data is here.
cdc.gov/fluvaxview/das…Image
3) It’s not just the flu that is going around… Gaines County, TX, where the epicenter of the measles outbreak is, has one of the lowest measles vaccination rates too.
Read 7 tweets
Eric Feigl-Ding Profile picture
Feb 11
INFLUENZA REACHES EPIDEMIC THRESHOLD in New York—Influenza A (Unknown variety) positivity soars (yellow), while hospitalizations stand higher than past 3 years. The rise of unknown subtyping Flu A has led NY to issue new alert to subtype all Flu A immediately for bird flu. Image
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2) This was the reason for the urgency in NY issuing an alert to subtype all hospitalized cases for bird flu if Flu A. See thread below 👇
3) the testing memo seems very aggressive for bird flu.
Read 7 tweets
Eric Feigl-Ding Profile picture
Feb 10
BREAKING—22 States sue to block Trump WH cuts to NIH research grants. Image
2) Attorneys general representing 22 states sued the Trump administration on Monday, asking a federal judge to temporarily block a major policy change by the National Institutes of Health that would substantially limit payments for research overhead

statnews.com/2025/02/10/nih…
3) In the lawsuit, filed in U.S. District Court for the District of MA, the AGs argued that NIH’s abrupt decision to set a 15% cap on payments for indirect costs would cause major harm to institution budgets, jeopardizing basic operations and medical research.
Read 5 tweets
Eric Feigl-Ding Profile picture
Feb 8
💣TORPEDOING MEDICAL RESEARCH—NIH indirect grant funding just got slashed by Trump to 15%. What does this mean for you? Colleges and universities won’t be able to support students, tuition will increase, especially graduate students & researchers who find cures/preventions for cancer, diabetes, heart disease, Alzheimer’s and more. This will not only raise tuition and hurt pipeline of future scientists/doctors, but COMPLETELY DECIMATE MEDICAL & PUBLIC HEALTH RESEARCH. It will also give more power to big pharma to manipulate research agendas and buy out ideas that should remain in the public domain. Ie THE RICH BIOTECH TYCOONS (eg Vivek Ramaswamy) WILL GET RICHER. The lay public will someday only see future drug/tech prices soar as biotech and big pharma control more science and make more money.

Also, Trump’s NIH posted this graphic - but it ignores that most public universities also heavily rely on indirect to subsidize tuition, and train next generation of scientists and medical doctors doing research. (Public colleges can’t compete with wealthier schools who do have endowments, and hence will fall further behind). Public colleges that do medical research will literally fall apart without this mechanism.Image
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2) People don’t seem to get 2 things:

📌Indirect funds college administration and facilities and support services. Academic advising, building operations, new labs and classrooms for students— where does that money come from? If not indirect grants, then it’ll have to come more from ⬆️student tuition.
3) Most universities don’t have billion+ endowments. Most have almost none — so when you slash NIH indirect grant funding to just 15%… it hurts small schools and public colleges the most—smaller places might even go under. Rich school survive, public schools do not.
Read 4 tweets

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