Hannah Davis Profile picture
Mar 10 5 tweets 3 min read
More evidence that you're not out of the woods if you initially recover from COVID!

In a group of COVID patients, 43% had *delayed* onset of cognitive #LongCovid (1-6 months after infection). The delay was associated with a *younger* age (average 39).

ncbi.nlm.nih.gov/labs/pmc/artic… 1/
This supports our @patientled data showing that the onset of neurological #LongCovid symptoms often happen later after the acute onset, especially between 1-3 months later:



2/
From the first paper: "Mechanisms that may have a delayed onset include microvascular injury, persistent immune activation, and a post‐infectious autoimmune response." #LongCovid

3/
@exceedhergrasp1 thought you might be interested re: the delayed onset
Addendum: this is not a prevalence study, as all patients ended up being #LongCovid patients!

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Hannah Davis

Hannah Davis Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @ahandvanish

Mar 10
There's a big reality gap right now between people who are actively staying on top of COVID research & those who just trust the current guidelines. There's no judgment here, but I'd like to try to communicate the worldview of the former based on what we know about COVID now:

1/
The US has chosen to prioritize the economy despite strong, countless studies that COVID harms many people, even those without #LongCovid or hospitalization. COVID predominantly affects the *vascular* system (the blood vessels), causing harm to the blood cells & blood flow;

2/
this has a downstream impact on nerves, immune system, & multiple organs, including the brain. Vaccination prevents against death, but not against long term damage.

3/
Read 13 tweets
Feb 11
I think a lot of people assume #LongCovid is a continuation of the acute COVID symptoms, that just take a long time to get over.

In reality it is an often delayed onset of *new* neurological, immunological, cardiovascular, and systemic symptoms.

1/
We know a lot about #LongCovid by now. We know it has complex, multi-systemic, interlinking causes, including microclots, deformed blood cells, immune system dysfunction, dysfunction of mitochondria (which are responsible for energy production - dysfunction is a big deal!)

2/
We know enough about #LongCovid to know it's not a simple illness, & is causing major systems of the body to become dysfunctional in ways that medicine is not yet advanced enough to fix.

We know for many manifestations, incl dysautonomia, microclots, ME/CFS, there is no cure. 3/
Read 7 tweets
Feb 7
Some evidence suggesting that #LongCovid patients might be more susceptible to breakthrough infections:

1/
“The team found that [LC patients have more autoantibodies], & that as autoantibodies increase, protective SARS-CoV-2 antibodies decrease. This suggests a relationship between #LongCovid, autoantibodies and patients at elevated risk of re-infections.” 2/

bloomberg.com/press-releases…
“Many patients with high autoantibodies simultaneously have low (protective) antibodies that neutralize SARS-CoV-2, and that’s going to make them more susceptible to breakthrough infections,” said Daniel Chen, a co-first author of the paper.” #LongCovid

3/
Read 4 tweets
Feb 4
Thank you to Mike for this piece on our #LongCovid work at @patientled & @itsbodypolitic in the context of what we're up against: a long history of medical gaslighting. Many illnesses (AIDS, cancer, MECFS, colitis, MS) were dismissed before their biomedical cause is found. 1/
The toll of doing advocacy in this environment is high (for us now, & also everyone who came before us).

It's been hard for me to be this vulnerable about this experience so extra thanks to @mikesmariani - a #pwME himself - for treating this topic with grace. 2/
The gaslighters are loud, but they're a minority. And they are quickly being shown to be not just historically cliched, but medically wrong, given how much #LongCovid research is already available. 2 years into this we already have evidence of...

3/
Read 7 tweets
Feb 1
Thank you so much to @RepPressley for meeting with leaders of the #LongCovid & disability community to talk about major treatment, research, and policy needs, and her call to the CDC to #CountLongCovid!

Our full conversation is available here:

1/
Thank you to all the advocates (representing @patientled, @itsbodypolitic, @C19LH_Advocacy, @UTc19LongHaul & others) who spent energy giving amazing testimonies: @LisaAMcCorkell, @chiluvs1, @netiamccray, @LisaOBrienn, @SeeMiaRoll, @K_Bishof, @rubyslippahs, @annwlace409 & Molly 2/
A thing that stood out to me: Dr. Bateman (1:02:59), who spent her career seeing v disabled ME patients, saying:

"I was completely stunned by the disability & severity of illness in #LongCovid...the amount of cognitive impairment & physical impairment is just unbelievable."

3/
Read 6 tweets
Jan 5
Getting an illness that has been unnecessarily politicized is a nightmare.
I don’t want to deal with trolls and harassment for making threads about biomedical papers.
(and obviously there are many politicized illnesses, #LongCovid is just one. but one everyone wants to have an opinion on)
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us on Twitter!

:(