My next foreshadowing is granular; the increased rate of severe disease in those with previously more moderate courses due to the loss of naive T cells in those without early, sera-mediated control of SARS Cov 2.
A solitary loss of naive T cells would not cause immunocompromise
On the contrary, it would cause immune overexuberance
My published statement is that Naive T cells dampen effector responses
You guys get another thing wrong. The T cell 'exhaustion'
In sars cov 2 infection, that is a way of preventing overshooting activation in the younger population.
These are, on the surface, paradoxes, until the mechanism is understood
SARS Cov 2 burns the T cells at both ends, killing terminally differentiated via FAS and precociously aging the Naive by bystander activation and the feed-forward controller, but this manifests in immune exuberance.
from 2020. More severe reinfections from a contraction of the Naive T cell population.
However, unpublished, I have suggested that harm to the CD8 repertoire could mean people were worse at fighting EBV, HPV, and some immunogenic cancers.
As soon as the preprint dropped we were on it and the usual minimizers tried to convince it was meaningless. Balloux, JasnahKholin, SZ, because they are on the side of the economic interests that want you to unmask to gain immunity by infection
We all know that doesn't work...
A lot of idiots think that you will gain immunity against this by infection, and if you are reminded that you are getting brain damaged you won't fall into their scam, so they minimize
Ultimately you will just save on pensions if you keep getting infected