2) this is now cases and hospitalization in UK which has been #BA2 dominant for many weeks. England hospitalizations is already approaching their December peak… and surged quite quickly after cases rose I might add (perhaps under testing during early surge?)
3) England lifted all restrictions on Feb 24th… cases surged again. This coincided with also #Ba2 surge. So England is having a double whammy of both dropping mitigation and BA2 at the same time. Way to effing go @BorisJohnson
4) another worrisome thing is that reinfection % rate has also begun to recently spike in England 🏴— coinciding with the surge in BA2 and cases— Especially worrisome since UK is surging after a recent BA1 Omicron wave. This is the stuff that I ponder at night why.
5) Also fascinating is that in the 🏴 December #Omicron wave, hospitalization rate trailed cases and was about 2% of cases at the peak, but now it’s significantly outpacing 2% in the new surge. This may not mean it’s more severe—more likely cases are heavily under-diagnosed.
6) has testing dropped in the UK? Yes by quite a bit, but testing per capita in UK is still significantly higher than the US. UK wave is definitely real (cases surging despite testing dropping is usually a bad sign). But the quick surge in 🏴 hospitalizations is very worrisome.
7) As #BA2 grows, it will displace the older variant. You will not see a surge until the new variant overtakes the old. This is why US isn’t surging overall yet because BA2 still under 50%. Wait for the crisscross—that’s when it plateaus & reverses.
8) however, there is a matter of both when the criss-cross of the old #BA1 vs new #BA2 variant will occur. Some think late March or early April. And there is debate how quickly uptick will be afterwards—spring outdoor friendly weather could slow it. But no mask can accelerate it.
9) Ontario 🇨🇦 just hit around ~50% #BA2 this week. So how are things looking in Ontario? Their wastewater is now showing #SARSCoV2 resurgence province-wide, right on cue. Wastewater increase almost always precedes case rise in 1-2 weeks. Data doesn’t lie. covid19-sciencetable.ca/ontario-dashbo…
10) In the annals of history… don’t be the dismissive person who history looks back with scorn for having dismissed #COVID19 whenever clearly #CovidIsNotOver. Yet many believe act with arrogance 👇
11) Danish officials got arrogant about #BA2 and this is their epic failure. Not only COVID deaths increased but also EXCESS deaths increased substantially. That is an epic fail if you ignore BA2.
12) Speaking of COVID deaths… yes, #BA2 is now driving increased deaths again in the UK. But do we honestly need to wait to see deaths before we act damnit?!?!
I’ve said it before, and I’ll say it again… once upon a time, liberals did have our own “Leftist Joe Rogan”… his name was Joe Rogan…
Here he is advocating for socialized medicine, healthcare for all, and supporting labor unions to protect workers.
2) Recall, Rogan was once pro Obama and pro Bernie Sanders, and pro Yang Gang, and anti Trump. It’s sad he has since failed to the dark side. But like Vader… maybe he can be redeemed someday and come back to the light.
Joe Rogan was also pro gay rights and pro DACA and pro helping inner city communities that suffer economic and social injustices. It’s sad what he has become. I feel we should try to pull & welcome him back someday. Everyone can be redeemed.
BREAKING—FDA suddenly cancels meeting to update next season’s flu vaccines, with zero explanations. Any delays will jeopardize next year’s vaccine supply chain.
2) Folks who follow me know that I’m no bullshitter. I criticized past pandemic response right and left, and have called balls and strikes without bias. And I often say things that doctors & epidemiologists are whispering among themselves but don’t say publicly. (Cough cough) ⬇️
3) While I don’t recommend hoarding… I think stocking up on flu antivirals, which you can obtain prophylactically (preventively) from doctors if you ask nicely why you’re high risk, can be a good idea. I know many doctors, epidemiologists and virologists who do for their family.
Doctors are debunking RFK Jr’s claim that 20 hospitalized measles cases in Texas are there for mainly quarantine. Doctors on the ground say the 20 kids hospitalized are having trouble breathing. Oh and they are all unvaccinated against measles, which RFK Jr neglects to mention.
2) RFK Jr told Trump today there’s now 2 measles deaths.
Woke or biology? There are actually more than the basic “male” XY & “female” XX sexes. Why? Because biology also creates people with single X chromosomes, or extra chromosomes like XXX, XXY, XYY, or XXX+, plus many 🧬genes. 👉All I’m asking is— please be kind to others. Thanks🙏
2) “The most frequent SCAs include Turner syndrome (45,X), Klinefelter syndrome (47,XXY), Trisomy X syndrome (47,XXX), and Double Y syndrome (47,XYY).”
3) “The phenotype seen in SCAs is highly variable and may not merely be due to the direct genomic imbalance from altered sex chromosome gene dosage but also due to additive alterations in gene networks and regulatory pathways across the genome as well as individual genetic modifiers.”
I'm shocked a lot of doctors don't know about this newer flu antiviral drug called Baloxavir (XOFLUZA)... that shortens your flu illness by 33%, and reduces your viral load by day 2, versus what a placebo takes 5-6 days to achieve. Baloxavir also seems superior to TAMIFLU (oseltamivir) for smashing your viral load on 2 day, achieving what takes Tamiflu 3-4 days. CDC even lists Baloxavir on their website as one of the top 4 drugs that it tracks whether it works against new flu strains (it works)
2) "Baloxavir was associated with significantly more rapid declines in infectious viral load than placebo or oseltamivir (Figure 3A and 3B)." nejm.org/doi/full/10.10…
3) Adverse events for baloxavir were no different than placebo. in fact theres even hints that it could be lower than Tamiflu.
"Adverse events that were considered to be related to the trial regimen were more common in oseltamivir recipients (8.4%) than in baloxavir recipients (4.4%, P=0.009)"