This is wrong from a biomedical and clinical perspective. Covid is not less dangerous than the flu even now, with vaccination. Covid is a multi-system disease, not just a respiratory condition. Having a test matters, because no test will mean poor access to appropriate care

🧵
In more details: it's true you can have upper respiratory symptoms, like sneezing, with covid. This is especially now with omicron ~ lot of prior immunity | lower respiratory tract infection may be less prominent | yet: covid is a multi-system disease | pneumonia remains possible
We also need to fully understand whether BA.2 and other emerging variants and sub-lineages, are intrinsically more pathogenic than omicron BA.1. And BA.1 was *not* "mild" or "the common cold". It is |was covid, fully able to kill and cause #LongCovid.
You can still have all sort of symptoms incl. gastrointestinal symptoms at onset already. Covid is a disease with a complex progression and potential degeneration = #LongCovid. While vaccination can help stop this, you need to remain vigilant even if early symptoms are "mild".
While it's true we can, according to certain criteria, classify SARS-CoV-2 as a respiratory virus based on mode of transmission = mainly airborne and with early infection of the respiratory tract, covid remains a multi-system disease, with a massive cardiovascular potential.
While seasonal flu can have, occasionally, severe complications and sequelae like pneumonia, #longflu, this is certainly not as common as with SARS-CoV-2 | covid. Not even close. #LongCovid | covid aren't the "sniffles" and some "cough". Please remain vigilant.
A final note on tests: we know from the 2020 wave that patients with no positive SARS-CoV-2 test had huge problems in accessing the right support for #LongCovid and related complications. Scrapping testing is a *massive* problem that will impact omicron patients badly.
Thanks @benking01 for signalling this to me!

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More from @elisaperego78

Apr 7
A great thread by @dgurdasani1 on where we are in terms of pandemic development
I strongly concur vaccination is great, but doesn't necessarily prevent infection, symptomatic disease, severe acute disease, fatal disease, and #LongCovid. We have already the data to show that

🧵
Omicron and sub-lineages have significant immune escape features that may lower, among other things, the efficacy of our vaccines. Immune escape was evident soon after omicron emerged. This was published, for example, in top @Nature in December 2021

nature.com/articles/s4158…
SARS-CoV-2 is still evolving at a fast pace. Actually, evolution seems to have accelerated as the virus spreads rapidly, largely uncontrolled, across the globe. The severity of future variants is unpredictable

nature.com/articles/s4157…
Read 5 tweets
Apr 7
Covid as a clotting disorder ||
Further evidence SARS-CoV-2 infection increases the risk of thrombotic events and other coagulation-related anomalies in both acute and #LongCovid || a large-scale study based on 2020 and 2021 cohorts

@bmj_latest 🧵

bmj.com/content/377/bm…
The authors report an increase in the risk of deep vein thrombosis, pulmonary embolism and bleeding with covid || risk of coagulation-related abnormalities persist for months after the first weeks of covid ~ as reported by the patient community > #LongCovid
As the authors themselves acknowledge, their data are based on analysis of medical records: it is well possible, thus, that thrombotic phenomena | coagulation problems are more common than reported in their research || spoiler from the #LongCovid patient community: yes! 👇
Read 6 tweets
Apr 7
SARS-CoV-2 is *very* airborne. Many people don't understand it. Public health officials aren't open about the mode of transmission. Most people have problems in grasping the extent and reality of airborne transmission. Policy makers must be clear about this
#COVIDisAirborne
Even people who understand the importance of masks, do not fully grasp the virus can stay in the air for a while even if the infected person has left. The cigarette smoke analogy is so good. People in position of power (policy, media, politics) should be open about this
Another issue is how fast the virus is at infecting you, even if you stay within with the virus-laden air for a relatively short period. So, we see people, for example, removing masks on flights to eat. Or, sadly, policy makers removing their masks to talk to journalists
Read 4 tweets
Apr 6
A review of #LongCovid as a thrombotic phenomenon. With discussion of endothelial injury, clotting, tissue hypoxia, lung vascular damage, platelet activation etc. || The authors address the need for early anticoagulant | antiplatelet therapy

🧵

frontiersin.org/articles/10.33…
A little note about patient-led research and the need for appropriate recognition of patient-driven expertise: many issues in the paper have been raised by the #LongCovid community starting already 2 years ago
Here some involved early @MartaEsperti @LongCovidItalia @JasmineHayer @ItsAngInLA @preshitorian | many others too |
@felicitycallard and I tackle some of these stories, and issues around expertise, in a review of patient-led contributions to covid science

osf.io/preprints/soca…
Read 9 tweets
Apr 6
A positive step forward from the @WhiteHouse and the Biden Administration on addressing #LongCovid. A formal statement is out on 5 April 2022.
I am grateful to the advocates and researchers, including the patient-researchers, who made this possible 💙 🧵

whitehouse.gov/briefing-room/…
I hope this roadmap to study and treat #LongCovid will be highly productive. I hope research will help people suffering from Long Covid to get their lives back. I hope research will be focused on treatment and care, in addition to simply quantifying the disease
I hope any cure, or treatment, or new knowledge, gained from the work envisioned in the roadmap, will be deployed to help marginalised communities, in addition to those with access to high-quality healthcare.

#LongCovid #TreatLongCovid
Read 4 tweets

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