2/ what is the left atrial appendage?

The LAA is derived from the left wall of the primary atrium (embryo). Its diff from the true LA and its suited to function as a decompression chamber during left ventricular systole and during other periods when left atrial pressure is high
3/ the appendage is like your fingerprint. No two are the same.

Common shapes are:

🥦Cauliflower/Broccoli (hardest)
💨Windsock (easiest)
🐓Chicken wing
🌵Cactus

#LAAO #Watchman #Structural #Cardiotwitter #EPeeps @EPeeps_Bot @TAVRBot @RadialFirstBot @EchofirstB
4/ even with its physiologic functions the LAA seems to propose more risk then benefit especially in the setting of atrial fibrillation.

About 15% of ischemic strokes arise as a result of atrial fibrillation #LAAO #Afib #CVA #stroke

Credit- Jaqueline Shaw, UBC
5/ OACs work well but still carry a 2-5% major bleeding risk/yr. So many factors contribute to ⬆️ bleeding risk and unfortunately many of those same factors share territory with afib. Many patients are left with either no anticoagulation or risk of repeat bleeding events.
6/ enter left atrial appendage occlusion- specifically The #Watchman

This device was designed to prevent stroke in afib patients that cannot tolerate anticoagulation (long term) #LAAO #Afib
7/Protect AF- After 3.8 yrs of f/u pts w/ nonvalvular AF ⬆️ risk for stroke, perc LAA closure met criteria for noninferiority and superiority, compared w/ warfarin, for preventing outcome of CVA, systemic embolism, and CV death, as well as superiority for CV+ all-cause mortality.
8/ the first device was novel but had many issues. It was hard to implant, and now we are finding has issues with late leaks and possible device thrombus #Watchman #LAAO
9/ the real winner- WATCHMAN FLX. As someone that has implanted both, this device has been the definition of a game changer. It’s easy to implant and the way it conforms the the appendage is must better than it’s previous ridged predecessor the 2.5 #LAAO @EPeeps_Bot
10/ PINNACLE FLX, SEAL FLX, and SURPASS have very promising data. We are still awaiting CHAMPION AF data but all signs point to the Watchman FLX as being a revolutionary change to the LAA closure space. #LAAO
11/ implantation truthfully is all about the #transseptal. A posterior and mid/Inf transseptal is preferred to access the anteriorally located appendage.

#LAAO @adnanalkhouli @Dr_Santangeli @epTicTocDoc @DrCJBradley @RajTayalMD @chadialraies @agtruesdell
12/I’ve started using the #VersiCross and man it’s an amazing way to cross. The sheath is well transitioned to get into the skin and then the moldable sheath engages the septal followed by exposure of the wire. RF ON! then push the wire forward and form a PIG tail in the LA
13/ next pick your right sheath (depends on anatomy)

12F ID and 75cm working length

➰Single curve
➿Double curve (used most often)
〰️Anterior curve

Use echo to choose. If LAA close to ventricle use single, if LAA curves towards atrium use anterior. Double- everything else
14/ get the sheath into appendage and place your PIG 🐷 . I usually perform appendage-o-gram to help me better understand appendage, however #echofiest should be your go to for complete understanding/assessment @EPeeps_Bot @epTicTocDoc @adnanalkhouli @SachinGoelMD @yourheartdoc1
15/ Next based on echo/CT pick your size

🔸20 mm
🔹24 mm
🔸27 mm
🔷31 mm
🔶37 mm

Your goal is to aim for somewhere between 10-30% compression. Use echo for assessment. @HafizaKMD @NirmanBhatia @SachinGoelMD @doconmoney @DrMarthaGulati @ekgpdx @djc795 @heartdoc45
16/ prep the watchman and place wet to wet into sheath. Get to the radio opaque line and pull the sheath back. FLX ball time!

This IMO has been one of the great advantages of FLX.

Keys
🔑 ball size should be about double the sheath
🔑 Notice how ball reacts, desheath or push
17/ deploy your device and hold forward tension for 10 sec. TEE for

PASS criteria..
P- position (ostium)
A- anchor (tug)
S- size (compression 10-30%)
S- seal (no leak >5mm)

@adnanalkhouli @yourheartdoc1 @epTicTocDoc @EPeeps_Bot @ekgpdx @RajTayalMD @Pooh_Velagapudi
18/ Counter-clock to release. The FLX allows you to recapture and reposition as many times as you want pull everything back into the IVC. Figure 8 stitch to close. Home the same day! #LAAO #Cardiotwitter
19/ 💊 OAC for 45 days

🔍followed by TEE or CT to confirm no device thrombus or leak

➡️then DAPT for 6 months after.

🙏🏾Hopefully coming data will let us drop the OAC 45 day post period

#Watchman #LAAO @EPeeps_Bot
20/ I’m excited for new techniques in the field as well! 4D volume ICE for LAAO. This would eliminate the need for anesthesia and TEE!

Video courtesy of @Dr_Santangeli

#ICE #LAAO
21/ watchman is another device in the structural interventionalists tool box!

We couldn’t do it without our amazing structural imagers and coordinators! The device is safe and can change a persons life! Excited to see the field continue to evolve. #Watchman #LAAO #McLarenHeart

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More from @DrJayMohan

Sep 30, 2023
1/ What features PRIOR to intervention are suggestive of adverse prognosis in acute PE?

Which marker do you suggest is the highest risk of poor outcome DURING intervention?

#Cardiotwitter #VTE #pe Image
2/ This is the list. I would suggest that a very large RV/LV ratio (>2) and presence of severe PH (PASP>60) yields significant risk during intervention

I know @AntoniousAttall has touched on this, but I would warn most operators extreme caution in this patient subset.

We don’t have a true list to assess during intervention!
Image
I would argue we need to look at more markers prior to intervention to indicate treatment in the expanding role of intervention.

Markers such as RA/RV ratio, more echo criteria (60/60 rule), pulmonary artery obstruction index (PAOI), and The Hounsfield Unit Values of Acute and Chronic Pulmonary Emboli have been suggested
Image
Read 5 tweets
Jul 3, 2023
1/ It’s #July!! Welcome aboard new fellows! Over the next few days I’ll post things that will be helpful as you start your training!

To start- a #tweettutorial on CATH LAB VIEWS!

🔑 LAO- left/right
🔑 RAO- ant/post
🔑 Cranial- distal
🔑 Caudal- proximal

#Cardiotwitter
2/ 🔑 to success

It’s not going to come easy! It’s all about repartition and practice! Learn a good pattern to follow!

Use the RCIS techs to your benefit! They know more than you right now! Focus on the basics!

#CathLab @RadialFirstBot @BotPci #Cardiotwitter #FellowBootCamp Image
3/ 🔑 to anatomy! Learn the simple tricks

⭐️ Side branches of the LAD= Diagonals (D) and Septals

⭐️ Side branches of the Lcx= Obtuse Marginals (OM)

⭐️ Side Branches of the RCA= Acute Marginals

#Cardiotwitter #Fellowbootcamp #Cardiology Image
Read 19 tweets
Mar 11, 2023
1/ Had a great time writing this @EPLabDigest article with @DrCJBradley

tinyurl.com/mryk3cwe

2️⃣ different perspectives (IC And EP) using different devices (watchman/ amulet) for LAAC in the community center.

Let’s take a dive into two different LAAC programs #Tweetorial
2/ #LAAC has come a long way over the past few years and now we have two main players in the space

🔸 @bostonsci #watchman
🔸 @AbbottNews #Amulet

Both are very effective and each has pros/cons

My center focuses on Watchman FLX while @DrCJBradley center focuses on Amulet… twitter.com/i/web/status/1…
3/ Historically #EPeeps has taken the driver seat in this space (rightfully so) due to experience with the LA/transeptal. HOWEVER the new gen #IC/structuralist have become a vital part of the team.

#LAAC programs require:
📌Implanter
🔎Imager
🧑🏼‍⚕️Anesthesiologist/Cath lab team… twitter.com/i/web/status/1…
Read 24 tweets
Nov 11, 2022
1/ For the fellows and #ACCEarlyCareer!

It’s a coronary thrombus! When to consider thrombectomy? What do you do? Let’s walk through this…#Tweetorial

#Cardiotwitter #Cardiology #STEMI
2/ Middle age patient with hx of CAD and PCI to LAD presents with significant SOB and elevated Hs-Trop. No chest pain. No ECG changes. Echo with inferior hypokinesis.

Here’s the diagnostic with a JR4.

Notice the filling defect in the RCA. This is thrombus. How do we know?
3/ Keys of #thrombus on angiogram

🔑 contrast staining
🔑 Lack of calcium on non con image
🔑 ovoid filling defect (complete lumen)

#Cardiotwitter #STEMI #TIMI
Read 25 tweets
Mar 11, 2022
1/ Atypical CLOT- a tweetorial

I recently saw a controversial tweet arguing against tx of chronic clot and restricting tx SOLEY to the CFV/iliac. While I agree (for the most part)- data is limited. At the end of the day we care about the pt, and not every pt is the same! Case➡️ Image
2/ Pathophysiology of chronic #clot formation.

It’s important to recognize the lesions that can form after a clot:

Spurs/Webs
Rokitansky/NIVL/fibrosis

Your pts CEAP >5 always consider for non thrombotic obstructions! Consider #IVUS if things don’t fit! Image
3/ Clot is in a constant state of evolution. #Fibrin—> #Collagen.
 
Unfortunately many patients present in the subacute or late phase of #clot development which hinders many of our treatment approaches.
 
7️⃣days- 20% collagen

1️⃣5️⃣ days- 50% collagen

2️⃣1️⃣days- 80% (!!) collagen Image
Read 19 tweets
Aug 9, 2021
3/ Clot is in a constant state of evolution. #Fibrin—> #Collagen.
 
Unfortunately many patients present in the subacute or late phase of #clot development which hinders many of our treatment approaches.
 
7️⃣days- 20% collagen

1️⃣5️⃣ days- 50% collagen

2️⃣1️⃣days- 80% (!!) collagen
Read 39 tweets

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