In 2016, Science published the structure of the #NuclearPoreComplex—the sole gateway for macromolecules to enter or exit the nucleus.
A new special issue builds on that work, presenting the structure in unprecedented detail. fcld.ly/jfvwxfe (THREAD) 🧵
A new special issue builds on that work, presenting the structure in unprecedented detail. fcld.ly/jfvwxfe (THREAD) 🧵
A composite structure of the cytoplasmic face of the human #NuclearPoreComplex provides a rich foundation for elucidating the molecular basis of #mRNA export and nucleoporin diseases, according to a new Science study. fcld.ly/3v012d9
In a new Science study, researchers present a near-atomic composite structure of the human #NuclearPoreComplex’s ~64-megadalton symmetric core. The findings provide a basis for future functional studies. fcld.ly/wgoa4cj
Using #AI, researchers in Science have generated an exhaustive repertoire of human nucleoporin structures and fit each into an improved, higher-resolution #cyroEM tomography map of the #NuclearPoreComplex. fcld.ly/fafiho2
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