A microscope on pandemics.
h/t @jvantill, @steeph, @PeterSpitters, @HMDatabase, @ArielKarlinsky, @hippopedoid.

🧵
1.Find age specific testing data and confirmed case fatality rates per given period of time.
2.Correlate confirmed #Covid19 deaths with reported excess mortality.
3.Correct the excess mortality rate for the fact that there is hardly any Influenza* around these days.
4.Combine all data in a spreadsheet (various equations with various unknowns) estimating general virus population prevalence.

*
5.Input calculated age specific infection risks, and time weighted vaccination% in a cross-sectional regression analysis.
6.Estimate regression parameters, that would describe mortality most likely caused by extraordinary #SARSCoV2 prevalence.

7.Validate results of the regression model with Human Mortality Database excess mortality over week-specific lower-quartile baseline for mortality 2010-2019.

@threadreaderapp please compile

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More from @falsel_net

Mar 29
Bij het sociaal-demografisch nogal gekleurde rapport over sterfte tijdens het eerste jaar van de Corona epidemie valt te overwegen dat een aantal medische- en ethische kwesties onderbelicht zijn gebleven.
Het eerste jaar van de Corona epidemie kenmerkt zich door het feit dat er geen Influenza- en RS virussen etc rondwaarden, als gevolg waarvan de zeer hoge sterfte uitsluitend kon worden toegeschreven aan de gevolgen van de #SARSCoV2 virusverspreiding.

➡️apps.who.int/flumart/Defaul…
Sterfte door Corona wordt door RIVM steeds schromelijk onderschat, waardoor betrouwbare schattingen slechts mogelijk zijn aan de hand van de wekelijks sterftecijfers van het CBS die vergeleken met 'verwachte' sterfte een nauwkeurig inzicht bieden in de werkelijke Corona sterfte:
Read 4 tweets
Jan 10
Probably a good idea to contain a Coronavirus.

h/t 🇳🇿

rnz.co.nz/news/in-depth/…
Probably a good idea to contain a Coronavirus.

h/t 🇳🇿

Incidence rate per 100.000 declining.
➡️public.flourish.studio/visualisation/…
Probably a good idea to contain a Coronavirus.

h/t 🇳🇿

Close to Zero Covid Southern Island.
Read 4 tweets
Jan 9
Observational analysis #Covid19 Netherlands.

Data 2021 Rivm:
Confirmed nCFRs, h/t @Datagraver: Image
Comparison multiple parameters #Covid19NL 2021.

Age stratified #SARSCoV2 testing data, confirmed and total Corona mortality, time-weighted fully vaccinated population at estimated 1,6% Coronavirus prevalence. Image
Multiple regression analysis #Covid19NL 2021.

R2 = 1 and, predictors significantly explain 95.4% of variance in observed population % mortality dependent on infection risk, vaccination coverage and age category.

Mortality% = -16.2 + 0.8 InfectionRisk% - 0.2 %Vaxx'd + 0.3 Age Image
Read 11 tweets
Sep 10, 2021
@roelgrif @SDicht Duidelijk is dat Delta veel besmettelijker is. Met name op basisscholen begint de incidentie nu pas te dalen. Veel scholen zullen mondneusmaskers weer verplichten, voorlopig. Er zijn nu ~1% kids in quarantaine, en per 25 leerlingen één docent(e). Image
@roelgrif @SDicht Schools reopened with prevention: Pooled-PCR testing students & staff, allowing for temporarily isolating, quarantaining Delta #SARS_CoV_2 variant infections.

Containing #DeltaVariant in the County: Image
@roelgrif @SDicht Kijk, je moet er natuurlijk wel wat voor doen. Incidentie #SARSCoV2 op de scholen begint in ieder geval nu ook in het Primair Onderwijs te dalen. We gaan het zien.. Soms na het weekend weer even een opleving van besmettingen onder vriendjes en vriendinnetjes of familieleden. Image
Read 56 tweets
Aug 30, 2021
Descriptive analysis #Covid19 dynamics April-August 2021.

Total population analyses might distinguish between indiviual- and group risk of infecion.

Data rivm sourced: Image
Summer 2021 allowed for easing #Nonpharmaceuticalinterventions.
Vaccination effort was geared up.
Alpha was mostly the dominant VOC.
outbreak.info/location-repor… Image
Given age-stratified #TestTraceIsolate population wide CaseFatalityRates (nCFR), estimates were compared to cbs reported excess mortality, adjusted for absence of Influenza etc, and compared to the rivm estimated prevalence of contagious people: Image
Read 16 tweets

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