1/The logical implications of common arguments against #COVID19 #vaccines are worth considering. I focus on some of them here.
2/Argument #1: The approval process is corrupt!

What part of the process, specifically, is corrupt and how is that different from the pathway that other COVID therapeutics followed? For example, was the process that authorized monoclonal antibodies like bebtelovimab corrupt?
3/What about the process oral medicines like Paxlovid followed? What that corrupt, too? Remdesivir?

Would you be willing to take those other products if you got a serious case of #COVID? If so, why not vaccines?

What was uniquely corrupt about the vaccine pathway?
4/Perhaps you are lodging a broader argument against drug development/approval generally? Fair enough.

But that raises a broader question: which non-COVID, FDA-approved medicines are you willing to take right now? Are there *any* that meet your non-corruption threshold?
5/Argument #2: these vaccines are a money grab for big pharma! Understood, and we can debate the appropriate economic return that pharmaceutical companies should enjoy for their manufacturing of COVID vaccines.
6/The question now is this: given the status quo, are you willing to forego the vaccines given their impressive safety/efficacy?

What about other blockbuster meds? Would you be willing to forego taking, say, Humira, if you had IBD even though is is a money maker?
7/Argument #3: Look at all the side effects! Yes, all medications have potential side effects.

Given that, what is your theory of medical harms/benefits? Is your standard that you will only take medicines that have *zero* side effects?
8/Probably not, since even individuals in placebo arms have side effects. So it must be that you think that the harms of #COVID19 #vaccines outweigh the benefits.

What is your basis for that belief? Have you subjected it to scrutiny in light of the billions of doses given?
9/Argument #4: The vaccines don't prevent every case! True--nothing in modern medicine is 100%.

If you require 100% effectiveness before taking a drug, what medicines/devices/surgeries would you use right now?
10/If your mother needed cancer treatment and the oncologist described the chemotherapy regimen as having "80% efficacy" would you urge her to walk out the door and hold out for 100% efficacy?
11/What vaccines do spectacularly well is reduce the *likelihood* that you'll suffer a severe case of COVID.

Nothing in public health *eliminates* the risk of something; the goal is to *reduce* the risk. In that regard, probabilities matter.
12/Want to see the real-world data from #Maine? Visit: maine.gov/dhhs/mecdc/inf…
13/Argument #5: The doctors pushing vaccines don't know what they are talking about! But these are the same doctors -- all of whom have vaccinated their own kids -- who you probably took your own kids too when they were sick.
14/Are you making a general claim that those doctors are, in fact, charlatans and that you were wrong to visit them in the first place? Probably not. So it must be that you're making a specific claim that, with respect to COVID19 vaccines, docs don't know what's up.
15/Will you forego all modern medicine?

And why is it that in this one area of expertise, they have fallen down on the job? Why, for example, do you trust doctors' knowledge on, say, heart attacks, but not when it comes to vaccines?
16/Argument #6: These vaccines were developed using cell lines derived from aborted fetuses! That is correct. And quite common in biomedical research. Indeed, a number of other very common drugs were tested in a similar fashion...
17/...including albuterol, Tylenol, Motrin, Benadryl, Lipitor, Claritin, and Prilosec, to name a few.

Should someone making this argument also forego those other drugs?
18/Should it matter that @pontifex has stated, "it is morally acceptable to receive Covid-19 vaccines that have used cell lines from aborted fetuses in their research and production process." vatican.va/roman_curia/co…
19/These are deliberately provocative questions, and thought processes are not always consistent.

I raise these to offer food for thought for those who might be on the fence when it comes to vaccines.

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More from @nirav_mainecdc

Jun 19
1/In recent days, the @US_FDA has authorized and the @CDCgov (via @CDCDirector) has recommended the @pfizer and @moderna_tx #COVID19 vaccines for
children 6m+.

Though the safety and effectiveness of the vaccines are quite impressive, I've seen a more fundamental question.
2/That is, "Why should I vaccinate my child against #COVID at all? After all, it isn't that severe in kids, and my kid already had it. Is #COVID19 in children really a big deal?"

I'd like to make the public health case for pediatric #COVID19 vaccines with @CDCgov data.
3/Let's start with the baseline number of cases among children. Many children have been affected by COVID throughout the pandemic.

All of these slides are from a recent @CDCgov #ACIP meeting and are publicly available here cdc.gov/vaccines/acip/…
Read 17 tweets
May 13
1/Here's where we stand with #COVID19 in #Maine right now.

There are 223 people hospitalized w/COVID, 35 of whom are in the ICU and 2 on a ventilator.

Two weeks ago, there were 143 hospitalized. One thing different now as compared to prior surges is the severity level.
2/In prior waves, the number of patients in the ICU and on ventilators grew in tandem with overall numbers. But here, we have not seen the same parallel growth in the most severely ill patients.

Two weeks ago, there were 34 patients in the ICU and 5 on ventilators.
3/So our growth in hospitalizations has come from non-ICU/non-ventilated patients. They are still ill--make no mistake--since they are hospitalized.

Generally, the composition of those who are hospitalized now are older vaccinated individuals and younger, unvaccinated ones.
Read 6 tweets
Apr 5
1/There are some signs that the the levels of #COVID19 in #Maine may be starting to increase.

First, the most recent set of wastewater surveillance results showed uniform increases in viral levels across the state. This is different from the episodic spikes we've seen before.
2/The latest wastewater reports are here:

maine.gov/dhhs/mecdc/inf…

and here:

covid.cdc.gov/covid-data-tra…
3/Second, hospitalizations have increased. As of this morning, there are 104 people in the hospital in #Maine w/#COVID19. Of them, 30 are in the ICU and 4 are on a ventilator.

These are nowhere near the levels that we saw in mid-Jan '22. But they are a recent increase.
Read 8 tweets
Mar 30
1/The @US_FDA and @CDCgov yesterday authorized 2nd #COVID19 #booster shots for certain individuals.

Here's a summary of who is eligible and what it all means.
2/A second booster of either the @pfizer or @moderna_tx vaccine is available for individuals 50 years and older at least 4 months after their first booster. content.govdelivery.com/accounts/USFDA…
3/Also, a second booster of the @pfizer vaccine may be given to those 12 and older who are immunocompromised at least 4 months after the first booster. content.govdelivery.com/accounts/USFDA…
Read 10 tweets
Mar 4
1/I’ve recently discussed the importance of having a plan to obtain #COVID19 therapeutics in case you contract COVID.

I’d like to expand on what these therapeutics are and what a plan of that sort looks like.
2/Getting #COVID19 used to mean isolation and perhaps hospitalization.

Today in #Maine, we have several treatment options available.

The key to successful treatment is *early testing* so you can receive *early treatment.*
3/In recent months, @US_FDA has authorized several medications for the treatment of mild-to-moderate COVID19.

The treatments vary—some are pills, some are infused.

And they vary by effectiveness, with some reducing #COVID19 hospitalization by >90%.
Read 18 tweets
Mar 2
1/Yesterday on @mainecalling, I discussed the continued importance of #COVID19 testing. Though the peak of the Omicron wave is behind us, we're not out of the woods yet.

Tests are more widely available now. Here are some options.
2/The federal government is providing 4 free tests to every household, delivered to your address by @USPS.

They’re easy to order: covidtests.gov
3/@MaineDHHS has partnered with @RockefellerFdn to provide 5 rapid at-home tests per household through the Project ACT program.

Again, they’re easy to order and delivered directly to your address: accesscovidtests.org
Read 5 tweets

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