Axel Hugo Theodor Theorell born #OTD in 1903.
Theorell, who dedicated his entire career to enzyme research, received the Nobel Prize in Physiology or Medicine in 1955 for discovering the oxidation enzyme and its effects.
His contribution also consisted of the theory of the toxic effects of sodium fluoride on the cofactors of crucial human enzymes.
Sodium #fluoride is an enzymatic poison. Useful when studying enzymatic processes. Stops it cold. 
Amazing critters, enzymes. -|- "ALP is an enzyme present in bone and liver cells and can be used to diagnose liver, bone and parathyroid disease."
"First, studies with adult rats have shown that chronic low-level fluoride exposure can lead to glomerular hypercellularity & mesangial cell proliferation, reduced kidney enzyme activity, interstitial nephritis, & renal tubule hypertrophy & hyperplasia."
"Increased apoptosis and tubular epithelial damage, including necrosis, have also been observed among children with high fluoride exposures. Chronic low-level fluoride exposure is also associated with decreased thyroid gland activity among children"
Ashley J. Malin, et al., Environment International - "Fluoride exposure and kidney and liver function among adolescents in the United States: NHANES, 2013–2016" sciencedirect.com/science/articl…
Theorell knew. onlinelibrary.wiley.com/doi/abs/10.100…
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